30/08/2026
🔬🎉 New publication in Science Advances!
We are excited to share that our latest work on Methylscape, popularly known as the “10-minute cancer test,” has been published in Science Advances, a prominent journal from the Science family!
Dr Abu Sina, Head of SINA Lab, at the School of Biotechnology & Biomolecular Sciences, UNSW Sydney is a co-inventor of the original Methylscape technology and co-corresponding author of this new study.
First reported in Nature Communications, Methylscape was developed as a rapid and potentially accessible approach to cancer detection by exploiting the unique properties of cancer-associated DNA methylation.
In this latest study, we take Methylscape a step further, demonstrating its potential not only for cancer detection, but also for tracking breast cancer progression, including through a low-cost, disposable electrochemical platform.
Importantly, the technology is now moving beyond academic research towards clinical translation and commercialisation, with clinical studies progressing in partnership with Resolve Health, USA.
A special thanks to our then PhD student Dr Emtiaz, Dr Zhen, Dr Nicolas, and the entire team and collaborators whose dedication and hard work have made this possible. 🙌
From a laboratory discovery to clinical studies and commercialisation, we are excited to see the “10-minute cancer test” moving closer to real-world impact!
Cancer progression is driven by epigenetic reprogramming, where promoter hypermethylation of tumour-suppressor genes and global hypomethylation reshape gene regulation and cellular phenotypes, promoting oncogenesis and disease advancement. We previously ...