Anesthesia

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Anesthesia and Pharmacology Study with Global Anesthesia Community development.

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Can remimazolam challenge propofol in pediatric fast-track anesthesia?

A new randomized trial in 101 children undergoing percutaneous ASD closure found that remimazolam achieved faster LMA removal (2.4 vs 10.4 min), lower PAED scores (less emergence delirium) and less intraoperative vasopressor use than propofol, while maintaining a similar overall safety profile.

Why does it matter for anesthesiologists?
• Faster airway recovery
• Less emergence delirium
• Better hemodynamic stability
• Comparable safety profile

Keep the limitations in mind: this was a single-center study including only ASA II children undergoing one specific procedure, with retrospective trial registration. These encouraging findings should be confirmed in larger multicenter RCTs before changing routine practice.

Remimazolam continues to emerge as one of the most promising intravenous hypnotics in modern anesthesia.

🇧🇷 🇵🇹 Um estudo com 101 crianças mostrou retirada mais rápida da máscara laríngea, menor delirium de emergência e menor uso de vasopressores com remimazolam versus propofol, mantendo perfil de segurança semelhante. Os resultados são promissores, mas ainda precisam de confirmação em estudos multicêntricos.

🇪🇸 🇲🇽 🇦🇷 🇨🇴 Un ECA con 101 niños mostró retirada más rápida de la mascarilla laríngea, menor delirio de emergencia y menor uso de vasopresores con remimazolam frente a propofol, con seguridad comparable. Se necesitan estudios multicéntricos.

🇩🇪 Eine randomisierte Studie mit 101 Kindern zeigte unter Remimazolam eine schnellere Larynxmasken-Entfernung, weniger Emergenzdelir und einen geringeren Vasopressorbedarf bei vergleichbarer Sicherheit.

🇷🇺 Рандомизированное исследование с участием 101 ребёнка показало более быстрое удаление ларингеальной маски, меньше делирия при пробуждении и меньшую потребность в вазопрессорах при использовании ремимазолама по сравнению с пропофолом.

Ref: Qin P et al. BMC Anesthesiol. 2026.

#Remimazolam #PediatricAnesthesia #Anesthesiology #Propofol #anesthesia 01/08/2026

Can remimazolam challenge propofol in pediatric fast-track anesthesia? A new randomized trial in 101 children undergoing percutaneous ASD closure found that remimazolam achieved faster LMA removal (2.4 vs 10.4 min), lower PAED scores (less emergence delirium) and less intraoperative vasopressor use than propofol, while maintaining a similar overall safety profile. Why does it matter for anesthesiologists? • Faster airway recovery • Less emergence delirium • Better hemodynamic stability • Comparable safety profile Keep the limitations in mind: this was a single-center study including only ASA II children undergoing one specific procedure, with retrospective trial registration. These encouraging findings should be confirmed in larger multicenter RCTs before changing routine practice. Remimazolam continues to emerge as one of the most promising intravenous hypnotics in modern anesthesia. 🇧🇷 🇵🇹 Um estudo com 101 crianças mostrou retirada mais rápida da máscara laríngea, menor delirium de emergência e menor uso de vasopressores com remimazolam versus propofol, mantendo perfil de segurança semelhante. Os resultados são promissores, mas ainda precisam de confirmação em estudos multicêntricos. 🇪🇸 🇲🇽 🇦🇷 🇨🇴 Un ECA con 101 niños mostró retirada más rápida de la mascarilla laríngea, menor delirio de emergencia y menor uso de vasopresores con remimazolam frente a propofol, con seguridad comparable. Se necesitan estudios multicéntricos. 🇩🇪 Eine randomisierte Studie mit 101 Kindern zeigte unter Remimazolam eine schnellere Larynxmasken-Entfernung, weniger Emergenzdelir und einen geringeren Vasopressorbedarf bei vergleichbarer Sicherheit. 🇷🇺 Рандомизированное исследование с участием 101 ребёнка показало более быстрое удаление ларингеальной маски, меньше делирия при пробуждении и меньшую потребность в вазопрессорах при использовании ремимазолама по сравнению с пропофолом. Ref: Qin P et al. BMC Anesthesiol. 2026. #Remimazolam #PediatricAnesthesia #Anesthesiology #Propofol #anesthesia

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