Allianz Research Institute

09/28/2024

Exciting news.

The FDA today approved Dupilumab or Dupixent, first biologic to treat COPD, a disease that is third leading cause of death world wide and 6th in the USA. This will further reduce exacerbation rate for the treatment of COPD. It’s a game changer for those suffering from COPD or smoking related lung disease.

For those who participated in our Notus copd trial for dupilumab. Your participation has made this possible.

Thank you.

If you are interested In other trials, please reach out to us.

https://investor.regeneron.com/news-releases/news-release-details/dupixentr-dupilumab-approved-us-first-ever-biologic-medicine?utm_campaign=regeneron+copd+fda&utm_source=linkedin&utm_medium=social

05/23/2024

We will start doing rsv testing as the cold and flu season starts up again

Contact us to learn more.

05/16/2024

For those who we’re immunocompromised patients volunteered for our Supernova covid prophylaxis monoclonal drug

Here the updated press release.

The drug helped prevent covid.

Once every 6 months.

Contacted us for other opportunities to volunteer in discovery great therapies for Asthma and COPD.

SUPERNOVA Phase III trial of sipavibart long-acting antibody met primary endpoints in preventing COVID-19 in immunocompromised patient population PUBLISHED 16 May 2024 Positive high-level results from the SUPERNOVA Phase III COVID-19 pre-exposure prophylaxis (prevention) trial showed AstraZeneca’s...

12/22/2023

Game changer In COPD

Amazing steps moving forward for dupilumab or Dupixent - Sanofi/Regeneron for COPD.

Both Boreas and Notus trial show benefits of Dupixent in reducing COPD exacerbation and lung function.

To be involved in such cutting edge research - IM us.

https://www.sanofi.com/en/media-room/press-releases/2023/2023-11-27-06-30-00-2785836

https://www.nejm.org/doi/full/10.1056/NEJMoa2303951

Original Article from The New England Journal of Medicine — Dupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts

10/02/2023

AirSupra (budesonide/albuterol)

A paradigm shift in asthma care
As needed Inhaled steroids is able

***reduce asthma exacerbation by 28%
*** improve Trough FEV1 or baseline lung function by 129 ml pre bronchodilator use

Compared to albuterol in mild moderate and severely asthmatics.

We were excited to participate as a a site in the Mandala trial and now help launch it.

08/19/2023

Nutrition plays an important role in lung health.

An apple a day keeps the doctor away.

A broccoli/Kale a day may keep
Pneumonia at bay.

https://www.medicalnewstoday.com/articles/cruciferous-vegetables-protect-against-lung-infection -is-AHR-and-how-does-it-affect-the-immune-system?

https://www.nature.com/articles/s41586-023-06287-y

A recent study shows that molecules naturally found in cruciferous vegetables like broccoli, cauliflower, and dark leafy greens may help the lungs maintain a healthy barrier against infection.

08/11/2023

EG.5 is now the most prevalent COVID-19 variant in the U.S. Its high transmissibility and ability to evade immunity has virologists following it closely—but it’s not quite time to panic.

06/22/2023

Infection today: H1N1, a type of flu that spreads among pigs, the World Health Organization said June 16 has claimed the life of a woman.

05/19/2023

The future of asthma and COPD. Precision application of Biologic therapy in lung injury and potential healing of the lung in asthma and COPD.

IL-33 - in clinical trials
https://www.frontiersin.org/articles/10.3389/fimmu.2020.01798/full

IL-17 - in clinical trial

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318387/

IL-13
(Dupixent in asthma FDA approved
And now pending approval for COPD with data from Boreas trial showing reduced exacerbation and Modest lung function improvement.

https://www.empr.com/home/news/drugs-in-the-pipeline/dupilumab-significantly-reduces-exacerbations-in-copd-trial/

To find out more about IL-33 trial at our site Allianz Research Institute.

Please respond below.

Treatment with dupilumab led to a significant 30% reduction in moderate or severe acute COPD exacerbations.

05/09/2023

Covid variant numbers rising in Asia
Singapore and South Korea.