Stubbs Lab at PNRI

Stubbs Lab at PNRI

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Investigating the Mechanisms and Evolution of Gene Regulatory Networks

Our research combines mouse genetics, bioinformatics and genomic methods to explore cis- and trans-acting components of mammalian gene regulatory machinery. We are particularly interested in those components of the regulatory machinery that have changed over evolutionary time. Working against a background of deep conservation, these changing components hold potential to explain biological differences between species, but also between different individuals in the same populations.

Is your stress level genetic? Local study examines the role played by DNA 03/02/2022

The Stubbs lab at the Pacific Northwest Research Institute was featured on KOMO News last night! Check out this short interview with Dr. Stubbs and learn more about our new study on the genetics of stress!

Is your stress level genetic? Local study examines the role played by DNA As worries about coronavirus start to ease, many people are left with other health conditions brought on by two years of living under the shadow of a global pandemic. Those include weight gain, depression, sleep issues, heavy alcohol and drug use are all up. A new study suggests that how one handles...

An epigenomic shift in amygdala marks the transition to maternal behaviors in alloparenting virgin female mice 02/22/2022

Hot off the virtual press! New paper from the Stubbs Lab at PNRI (Pacific Northwest Research Institute) : An epigenomic shift in amygdala marks the transition to maternal behaviors in alloparenting virgin female mice.

An epigenomic shift in amygdala marks the transition to maternal behaviors in alloparenting virgin female mice Adults of many species will care for young offspring that are not their own, a phenomenon called alloparenting. However, in many cases, nonparental adults must be sensitized by repeated or extended exposures to newborns before they will robustly display parental-like behaviors. To capture neurogenom...

01/13/2022

The Stubbs Lab at the Pacific Northwest Research Institute is hiring a postdoctoral fellow in , , and - Contact us now and join our team today!

An epigenomic shift in amygdala marks the transition from pup-aversive to maternal-like behaviors in alloparenting virgin female mice 05/17/2021

New Stubbs Lab preprint now available!
An epigenomic shift in amygdala marks the transition from pup-aversive to maternal-like behaviors in alloparenting virgin female mice

An epigenomic shift in amygdala marks the transition from pup-aversive to maternal-like behaviors in alloparenting virgin female mice In many species, adults will care for young offspring that are not their own, a phenomenon called alloparenting. However, most nonparental adults experience an initial aversion to newborns, which must be overcome before a robust display of parental-like behaviors can begin. To capture neurogenomic e...

Adapting to Stress: PNRI Science and Wine Club #2 April 2021 04/27/2021

Pacific Northwest Research Institute Scientist Lisa Stubbs, PhD explains the link between stress and health, and how it's all tied to our genetics.

Adapting to Stress: PNRI Science and Wine Club #2 April 2021 PNRI Scientist Lisa Stubbs, PhD explains the link between stress and health, and how it's all tied to our genetics.Chuck Reininger, co-owner and winemakers a...

Photos from Stubbs Lab at PNRI's post 03/24/2021

Pandemic Post Backlog 2/22/2021: Everyone tells you about all the rain in Seattle, No-one tells you about the constant rainbows!

03/24/2021

Pandemic Post Backlog 7/24/20: Our lab equipment has finally arrived safe and sound!

03/24/2021

Pandemic Post Backlog 6/29/20: Our New Home at the Pacific Northwest Research Institute in Seattle, WA!

03/24/2021

Pandemic Post Backlog 5/19/2020: Congrats to Dr. Chih-Ying Chen for defending her thesis over zoom!

"Dissecting the role of Auts2 and Galnt17 in neurodevelopment using a mouse model for human AUTS2 syndrome"

Lisa Stubbs Departs the University of Illinois | Carl R. Woese Institute for Genomic Biology 03/24/2021

Pandemic Post Backlog 4/7/2020: Stubbs Lab at PNRI departs Carl R. Woese Institute for Genomic Biology at the University of Illinois Urbana-Champaign for the Pacific Northwest Research Institute

Lisa Stubbs Departs the University of Illinois | Carl R. Woese Institute for Genomic Biology April 7, 2020 By: Alisa King Professor of Cell and Developmental Biology Lisa Stubbs, a pioneer in mammalian regulatory machinery, will be departing the IGB after serving for eight years as theme leader of the Gene Networks in Neural & Developmental Plasticity (GNDP) research theme to assume a vital...

03/24/2021

Pandemic Post Backlog 4/10/2020: Congrats to Dr. Chris Seward for defending his thesis over zoom!

Photos from Stubbs Lab at PNRI's post 03/24/2021

Stubbs Lab at PNRI field trip to the Woodland Park Zoo in Seattle, Washington!

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Pacific Northwest Research Institute, 720 Broadway
Seattle, WA
98122