UCSD Superfund Research Center

The UCSD-SRC is a multidisciplinary effort consisting of four Biomedical and two Environmental Science and Engineering Projects, all of which will use the highly specialized core resources of our Genetics and Metabolomics Research Support Core. Along with our Training Core which will provide career support to graduate and postdoctoral level trainees, the research and core components of our Center will work with the Research Translation Core (RTC) to promote our findings to broader based audiences, and the Community Engagement Core (CEC) to share our expertise with impacted communities.

Our Research

We will be investigating toxicants originating from industrial and consumer sources that lead to toxicant-induced steatohepatitis (TASH) and cancer. TASH is an escalating problem in many susceptible Hispanic and American Indian communities that are exposed to household, occupational and industrial chemical exposure. Our efforts will provide important findings linking mechanisms of TASH and cancer with disease prognosis, which can be communicated to impacted communities to serve as intervention tools to assist in prevention of toxicant exposure.

Overall, the central focus of our Center is to examine:

“The mechanisms leading to toxicant-induced steatohepatitis (TASH) are a combination of poor nutrition, health disparities and ongoing environmental toxicant exposure.”

Our Funding

The research conducted by our Center is supported by Grant Number P42 ES010337 from the National Institute of Environmental Health Sciences (NIEHS). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Environmental Health Sciences or the National Institutes of Health.