AAT Bioquest, Inc.

Dr. Sonal Patel and Dr. Helen Zhao giving a poster presentation about a unique method to achieve Fc site-specific conjugation that has been successfully used for labeling antibodies with a broad range of target molecules.

Follow the link to learn more!
👉https://docs.aatbio.com/resources/posters/a-new-fc-site-specific-labeling-technology-for-antibody-conjugation-cyto-2026.pdf

This study presents a two-pronged gene therapy approach that simultaneously boosts peak Na⁺ current and Ca²⁺ transient amplitude in cardiomyocytes to combat heart failure. It works by expressing prokaryotic sodium channels (BacNav), which modulate Na⁺/Ca²⁺ exchanger activity and increase sarcoplasmic reticulum calcium stores. In a mouse pressure-overload model of chronic heart failure, AAV9-delivered BacNav therapy rescued contractile deficit, prevented arrhythmias, and improved transcriptomic dysregulation. Our Cal-520 calcium indicator, was used to measure calcium transients in cardiomyocytes—loaded at 10 µM and imaged to track real-time Ca²⁺ dynamics during pacing experiments.

Congrats to Tianwu Yu et al on the publication. Your findings on rescuing cardiac function and preventing arrhythmias in chronic heart failure represent a truly exciting step forward for the field. We are honored that Cal-520 played a role in your research, and it is incredibly rewarding to see our products contribute to work of this caliber. We wish you continued success and look forward to supporting your future discoveries.

Read more
👉 https://www.science.org/doi/full/10.1126/sciadv.ady4551

Learn more about Cal-520 AM
👉 https://www.aatbio.com/products/cal-520-am

Introducing CYTOXite™ Green Dead Cell Stain — a no-wash, mix-and-read dye that lights up only when membrane integrity is lost. Zero background in healthy cells. Bright green signal in dead ones.

Perfect for:
🔬 Cytotoxicity screening
🧬 Membrane integrity studies
📊 Multiplexed cell health assays

Compatible with standard FITC filters (Ex/Em: 491/508 nm) and high-throughput platforms. Works solo or alongside proliferation & apoptosis assays.

Visit the link below to view the full product details, protocol, and SDS:
🔗 https://www.aatbio.com/products/15720

Using the wrong β-amyloid peptide can compromise your entire experiment.

Aβ variants aren't interchangeable — each has a distinct role:

🔬 Aβ (1–28) → Structural & binding studies
⚗️ Aβ (1–40) → Aggregation kinetics
🧫 Aβ (1–42) → Fibril formation & tissue pathology

Need to track localization or cellular uptake? Our fluorescently labeled peptides — FAM, Alexa Fluor, Cy, and iFluor® — let you image directly, no secondary reagents needed. Biotin and unlabeled formats also available.

👉 Our Beta-Amyloid Peptide Selection Guide is now live. Follow the link to find the right variant for your research:https://docs.aatbio.com/resources/flyers/beta-amyloid-peptides.pdf

AAT Bioquest will be at CYTO 2026 this June! 🌴☀️

Join us June 6–10 at the Palm Beach County Convention Center in West Palm Beach, FL. Stop by Booth #508 to meet our team, explore our latest flow cytometry reagents, and find the right tools for your research.

Whether you're working on cell viability, apoptosis, or immunophenotyping—we've got you covered. We'd love to connect and learn more about your work!

📍 Booth #508 | June 6–10, 2026 | West Palm Beach, FL

Will you be attending? Let us know in the comments! 👇

What an amazing few days at in San Diego! 🎉

We are so grateful for every single person who stopped by Booth #1819 to connect with our team — Dr. Sonal Patel, Helen Qin Zhao, Jerry S., and K Chico. Your enthusiasm and passion for advancing cancer research truly made this event unforgettable.

The conversations we had reminded us why we do what we do. Together, we're pushing science forward — and that's something worth celebrating. 🔬

Thank you, AACR community. We're heading home inspired, energized, and ready to keep innovating. See you next year! 🚀

Ask us about these research tools at

What does it take to truly decode the tumor microenvironment? The answer lies in having the right tools!

Here's a snapshot of the research tools we will be showcasing at AACR—fluorescence reagents for multiplexed tissue profiling, immunophenotyping, and spatial immuno-oncology workflows.

Want to learn more? Schedule a meeting with us! Email us your preferred days and times to [email protected]

Throwback photo of Dr. Sonal Patel and Dr. Helen Zhao at AACR 2025.

We are counting down the days until until . Only 2 weeks left — if you would like to connect and hear about our latest projects, send us a message to schedule a meeting. We'd love to see you there!

The cancer research community is coming together at in San Diego, and we will be there! Stop by Booth #1819 to meet our team, explore our latest products, and talk science. We can't wait to see you. 🧬