Having served as the founding editor of Oncogene from 1987 to 2008 and establishing Oncogene as one of the leading cancer journals, Dr. E. Premkumar Reddy launched the journal entitled Genes & Cancer in 2010 which publishes original studies and reviews that are relevant to all aspects of cancer research, signal transduction, and developmental biology. Its Editorial Board consists of outstanding scientists who are well known for their contributions in the fields of oncogenes/oncoproteins, signal transduction, cancer therapy and other fields of biology and medicine. One of the important goals of the Editorial Office is to shape this journal into a high impact journal. All papers appear in PMC and PubMed. Based on our calculation, Genes & Cancer will soon become a very high impact journal. Genes & Cancer is a member of the Committee on Publication Ethics (COPE) and other international committees.