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Report International Tuberculosis is a significant infectious cause of mortality and morbidity. Research is needed to identify biomarkers and measure efficacy of new tools.

Regional Prospective Observational Research in Tuberculosis International supports this global work.

The RePORT South Africa team describe a recent analysis which has revealed specific proteins/peptides in serum-derived  ...
09/01/2026

The RePORT South Africa team describe a recent analysis which has revealed specific proteins/peptides in serum-derived extracellular vesicles that were differentially abundant in individuals with early, asymptomatic TB. These findings highlight their potential as biomarkers and provide insight into host-pathogen interactions during subclinical infection. Read more!
https://pmc.ncbi.nlm.nih.gov/articles/PMC13085903/

08/24/2026

New research from our RePORT South Africa colleagues! 🇿🇦

By comparing blood transcriptomic and proteomic profiles across community screening and health facility-based triage cohorts, researchers have identified a new blood transcriptomic signature specific to asymptomatic TB.
Biomarkers developed for symptomatic TB triage don't necessarily translate to asymptomatic, community-based screening. As policymakers work toward better TB detection strategies, this research underscores the need for purpose-built, optimized biomarkers: not one-size-fits-all solutions.

Understanding these biological differences is a critical step toward more effective, equitable TB screening programs worldwide. 🌍

Link https://www.nature.com/articles/s41467-026-75909-6?cmid=b70dfd20-2946-482c-81d0-99b23c6e4889

A step forward in TB diagnosisWhen a common rapid TB test comes back "trace" or "very low," it's often unclear if that m...
08/18/2026

A step forward in TB diagnosis

When a common rapid TB test comes back "trace" or "very low," it's often unclear if that means real disease or just leftover DNA from a past infection - leading to missed or delayed treatment.

New research from teams in Uganda, Kenya, and South Africa identifies TRACE4, a simple four-gene blood signature that can help tell the difference — outperforming 13 other gene signatures tested. With further validation, it could become a fast, point-of-care tool to help clinicians act sooner for patients who truly have TB.

https://www.ijidonline.com/article/S1201-9712(26)00398-X/fulltext

Check out our August Newsletter with some very exciting updates and videos!We celebrate Dr. Jerrold Ellner’s 50th year i...
08/13/2026

Check out our August Newsletter with some very exciting updates and videos!
We celebrate Dr. Jerrold Ellner’s 50th year in TB Research with a special interview with Dr. Sonali Sarkar, JIPMER.

https://reportinternational.org/wp-content/uploads/2026/08/RePORT-August-2026-Newsletter.pdf

Today is International Youth Day.  There are many inequities affecting children, including access to care for preventabl...
08/12/2026

Today is International Youth Day. There are many inequities affecting children, including access to care for preventable infections, testing, and treatment. WHO’s 1+1 Initiative, comprised of more than 90,000 young people, has worked to raise awareness, challenge stigma, and mobilize communities for stronger action against TB. https://www.who.int/initiatives/who-1-1-initiative

It's a wrap!  The 15th Annual RePORT India Annual Meeting in Puducherry ended successfully with an array of science, net...
08/04/2026

It's a wrap! The 15th Annual RePORT India Annual Meeting in Puducherry ended successfully with an array of science, networking, and cultural programming!

We are at the 15th RePORT India Annual Meeting in Puducherry!
07/30/2026

We are at the 15th RePORT India Annual Meeting in Puducherry!

Read our July Newsletter here!https://reportinternational.org/wp-content/uploads/2026/07/RePORT-July-2026-Newsletter.pdf
07/20/2026

Read our July Newsletter here!

https://reportinternational.org/wp-content/uploads/2026/07/RePORT-July-2026-Newsletter.pdf

Stay informed with the RePORT International Weekly E-Bulletin! 🔗 Read the latest edition: https://conta.cc/4oLSKIdIn thi...
06/26/2026

Stay informed with the RePORT International Weekly E-Bulletin! 🔗 Read the latest edition: https://conta.cc/4oLSKId

In this week's edition, you'll find updates on global research partnerships, opportunities to nominate leaders in integration and care, new resources for digital health implementation and One Health approaches, funding opportunities for innovators, and initiatives to improve public engagement with TB science.

To receive future editions directly in your inbox, we encourage you to register for our listserv.

We need to think innovatively about preventing, diagnosing, and curing TB.  See how others are revolutionizing science s...
06/23/2026

We need to think innovatively about preventing, diagnosing, and curing TB. See how others are revolutionizing science so you can think about how TB elimination fits in. Check out this National Academy of Sciences event on June 25.

Revolutions in Science: Discovery, Imagination, and the Future As the United States marks its 250th anniversary, the National Academy of Sciences will convene scientific leaders, innovators, and emerging researchers to explore a central question: What discoveries will define the next 250 years? Revo...

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