This page will provide updates on current research in the Farber laboratory at Columbia University and a forum to connect former and present lab members.
12/08/2018
Check out updates and links to new publications on the Farberlab website
Farber Lab The Farber Lab is located in the Columbia Center for Translational Immunology at the Columbia University Irving Medical Center. Dr. Farber is in the Department of Surgery and the Department of Microbiology and Immunology at the Columbia University Vagelos College of Physicians and Surgeons. The lab...
07/24/2018
We have a new lab website! Check it out:
Home The Farber Lab is located in the Columbia Center for Translational Immunology at the Columbia University Irving Medical Center. Dr. Farber is in the Department of Surgery and the Department of Microbiology and Immunology at the Columbia University Vagelos College of Physicians and Surgeons. The lab...
02/21/2018
Our review on human T cell development, localization and function is published today in Immunity
Human T Cell Development, Localization, and Function throughout Life Recent studies of human T cells in diverse tissue sites have revealed that the functional role of T cells is closely linked to the anatomical location, subset, and developmental stage. Kumar et al. review these advances and highlight human-specific aspects of T cell immunity.
01/21/2018
Our paper on lung tissue resident memory T cells and allergic asthma is published online in the Journal of Immunology, with Damian Turner as first author and in collaboration with Drs. Monica Goldklang and Jeanine D'Armiento
Biased Generation and In Situ Activation of Lung Tissue-Resident Memory CD4 T Cells in the Pathogenesis of Allergic Asthma Asthma is a chronic inflammatory disease mediated by allergen-specific CD4 T cells that promote lung inflammation through recruitment of cellular effectors into the lung. A subset of lung T cells can persist as tissue-resident memory T cells (TRMs) following infection and allergen induction, althoug...
12/06/2017
Brahma Kumar successfully defended his thesis. Congratulations Brahma on this outstanding accomplishment!
09/21/2017
Our study identifying a unifying signature for human tissue resident memory T cells was published in Cell Reports
09/09/2017
Our study on validating the use of organ donor tissues for immunology research is published today by the American Journal of Transplantation
Human immunology studies using organ donors: Impact of clinical variations on immune parameters in tissues and circulation Organ donors are sources of physiologically healthy organs and tissues for life‐saving transplantation, and have been recently used for human immunology studies which are typically confined to the sampling...
Our study on mechanisms for altered infant respiratory immunity was published today in the Journal of Experimental Medicine
Reduced generation of lung tissue–resident memory T cells during infancy Infants suffer disproportionately from respiratory infections and generate reduced vaccine responses compared with adults, although the underlying mechanisms remain unclear. In adult mice, lung-localized, tissue-resident memory T cells (TRMs) mediate optimal protection to respiratory pathogens, and…
08/29/2017
Our collaborators on our NIH program grant, Drs. Nina Luning-Prak (UPenn), Uri Hershberg (Drexel) and Mark Shlomchik (U. Pitt.) just published an elegant study revealing B cell clonal distribution throughout the human body.
http://www.nature.com/nbt/journal/vaop/ncurrent/full/nbt.3942.html
An atlas of B-cell clonal distribution in the human body : Nature Biotechnology : Nature Research
08/19/2017
Elemental Haiku in Science magazine
Elemental haiku Author Mary Soon Lee (marysoonlee{at}gmail.com) provides this review of the periodic table composed of 119 science haiku, one for each element plus a closing haiku for element 119 (not yet synthesized). The haiku encompass astronomy, biology, chemistry, history, physics, and a bit of whimsical flair
06/30/2017
Presented symposium talk and one of the Keynote lectures at the Japanese Association for Cancer Immunology annual meeting in Chiba, Japan. Thank you to the wonderful hosts, Dr. Naoto Hirano and Professor Toshinori Nakayama, President of the JACI
http://jaci21.umin.jp/
第21回日本がん免疫学会総会 第21回日本がん免疫学会総会公式サイト
06/18/2017
Farber Lab members presented at the Federation of Clinical Immunology Societies (FOCIS) annual meeting this week in Chicago, IL