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Downstream Processing (Part 1) -Cell Disruption Methods - Intracellular Products | Dr. Deepika Malik 07/02/2023

Welcome to the first session of Downstream Processing! In this educational video, we will look at the critical features of the downstream processing recovery process, with a specific emphasis on cell disruption approaches.

Choosing the correct recovery procedure is critical for obtaining desired products from biological sources. We'll look at the aspects that influence this decision-making process, such as product characteristics, cost-effectiveness, and scalability. Understanding these factors will provide you with useful insights into optimising your downstream processing activities.

Following that, we'll look at the numerous types of cell disruption, which are essential for freeing intracellular components from cells. The following cell disruption strategies will be discussed:

Physical Methods: Learn how to use physical forces such as temperature, pressure, and osmotic shock to break open cells and liberate their contents. We'll look at methods including heat treatment, sonication, and high-pressure homogenization.

Explore mechanical approaches such as bead milling, high-speed homogenization, and high-pressure extrusion. Discover how these procedures effectively destroy cell walls and membranes, enabling efficient product recovery.

Chemical Methods: Investigate chemical substances capable of disrupting cell structures. We will discuss the application of enzymes, detergents, and organic solvents, emphasising their modes of action and applicability for certain applications.

Biological Methods: Investigate novel techniques to cell disruption that make use of biological agents. This section will include enzymatic therapies, viral lysis, and the use of microorganisms to aid in cell collapse.

By the end of this course, you will have a thorough understanding of the downstream processing recovery mechanism and the many cell disruption methods accessible. Join us on this trip as we provide you with the information and tools you'll need to run successful downstream processing operations.

Don't forget to like this video and subscribe to our channel if you want to learn more about downstream processing approaches. Stay tuned for Session 2, when we will look at further downstream processing processes, including as separation and purification procedures.

https://youtu.be/u_HB8myeE-I


Downstream Processing (Part 1) -Cell Disruption Methods - Intracellular Products | Dr. Deepika Malik Welcome to the first session of Downstream Processing! In this educational video, we will look at the critical features of the downstream processing recovery...

10/14/2020

Great News Folks !

The Department of Home Science & Department of Microbial and Food Technology, Mehr Chand Mahajan DAV College for Women are organising a National Level Competition on the occasion of *World Food Day*.

• Last day for Registration: 16th Oct 2020
• Last day for Sending Entries : 18th Oct 2020

Hurry ! Now
https://forms.gle/AAhAA4NdnNAm7VM28

Cash prizes will be awarded to the winners and e-certificates to all the participants.

For any queries please contact :

Dr. Harjot Kaur Mann : 9501202881
Ms. Rati Arora 9464656728
( Cookery and Rangoli )

Dr. Gurpreet Kaur : 9888115798
Dr. Deepika Malik
Dr. Sandeep Kaur
( Poster and Article )

06/17/2020

“No matter how big a nation is, it is no stronger than its weakest people, and as long as you keep a person down, some part of you has to be down there to hold him down, so it means you cannot soar as you might otherwise.”

– Marian Anderson

06/16/2020

What are the intrinsic factors for the
microbial growth ?

Let's check your knowledge ! Hurry.....

Scientists Clone SARS-CoV-2 Genome with Quick Yeast-Based Method 05/08/2020

Researchers have generated a full-length clone of the novel coronavirus genome using artificial chromosomes in brewers’ yeast, according to a paper published in Nature.
Read this to know more

Scientists Clone SARS-CoV-2 Genome with Quick Yeast-Based Method The use of yeast artificial chromosomes has enabled the rapid genetic reconstruction of the novel coronavirus.

2019 Novel Coronavirus (2019-nCoV) Update: Uncoating the Virus | ASM.org 04/18/2020

Uncoating the Virus /

I always tell my students, friends and family members that “microbes don’t read the book” with regards to our understanding them. The microbes don’t read or listen to social media either.

Try to stay informed, and listen to experts and sources that do offer facts but not sensationalism.

- American Society of Microbiology

American Society for Microbiology

2019 Novel Coronavirus (2019-nCoV) Update: Uncoating the Virus | ASM.org Decades of coronavirus studies provide a blueprint for the 2019 novel coronavirus. We summarize coronavirus biology, CDC recommendations, and global heath implications for the nCoV2019 outbreak.

04/13/2020



Quote Of the Day !
Always trust a microbiologist because they have the best chance of predicting when the world will end.

- Teddie O. Rahube

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