Yale Dermatology

Characteristic Distinctions Between Pre-/Post-COVID-19 Teledermatology Adoptees: A Cross-Sectional United States-based Analysis and the Implications for Dermatologic Healthcare Equity - JDDonline - Journal of Drugs in Dermatology INTRODUCTION The COVID-19 pandemic prompted many dermatologists to adopt teledermatology to continue patient care.1 Studies have since raised concerns regarding potential heterogeneity in telemedicine adoption and healthcare inequity exacerbation.1-3 The...

JCI - Identification of a neutrophil-specific PIK3R1 mutation facilitates targeted treatment in a patient with Sweet syndrome Address correspondence to: Thomas H. Leung, Department of Dermatology, University of Pennsylvania, 421 Curie Blvd., 1006 BRB, Philadelphia, Pennsylvania1a 9104, USA. 215.898.7013, [email protected].

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Factors affecting outcomes of second intent healing of nasal defects after Mohs micrographic surgery - Archives of Dermatological Research Reconstruction of nasal defects secondary to Mohs micrographic surgery (MMS) presents particular challenges related to the complex topography, skin quality, tissue laxity, and functional and aesthetic concerns of the region. Factors affecting outcomes resulting from second intent healing (SIH) on th...

Treatment at high-volume facilities is associated with improved overall survival for patients with cutaneous B-cell lymphoma Journal of the American Academy of DermatologyVolume 88, Issue 1, January 2023, Pages 203-205Research letterTreatment at high-volume facilities is associated with improved overall survival for patients with cutaneous B-cell lymphomaAuthor links open overlay panelShayanCheraghlouMDNelsonUgwuMDMichael...

Acral hemorrhagic Darier disease: A case report of a rare presentation and literature review The new PMC design is here! Learn more about navigating our updated article layout. The PMC legacy view will also be available for a limited time.

Utilization, cost, and prescription patterns of dupilumab among Medicare beneficiaries in the United States from 2017 to 2019 Published in Journal of Dermatological Treatment (Vol. 33, No. 8, 2022)

Targeting ULK1 decreases interferon-γ-mediated resistance to immune checkpoint inhibitors Abstract. Immune checkpoint inhibitors (ICIs) have transformed the treatment of melanoma. However, the majority of patients have primary or acquired resistance to ICIs, limiting durable responses and patient survival. Interferon-gamma (IFNγ) signaling and the expression of IFNγ-stimulated genes co...

Reduced blood-brain barrier pe*******on of acne vulgaris antibiotic sarecycline compared to minocycline corresponds with lower lipophilicity BackgroundVestibular side effects such as dizziness and vertigo can be a limitation for some antibiotics commonly used to treat acne, rosacea, and other dermatology indications.ObjectiveUnlike minocycline, which is a second-generation tetracycline, sarecycline, a narrow-spectrum third-generation tet...

Development and validation of an electronic health records‐based opioid use disorder algorithm by expert clinical adjudication among patients with prescribed opioids Background In the US, over 200 lives are lost from opioid overdoses each day. Accurate and prompt diagnosis of opioid use disorders (OUD) may help prevent overdose deaths. However, International Cla...

Extensive blaschkoid macules and patches since birth The new PMC design is here! Learn more about navigating our updated article layout. The PMC legacy view will also be available for a limited time.

Longitudinal single-cell analysis of a patient receiving adoptive cell therapy reveals potential mechanisms of treatment failure Adoptive cell therapy (ACT) using tumor infiltrating lymphocytes (TIL) is being studied in multiple tumor types. However, little is known about clonal cell expansion in vitro and persistence of the ACT product in vivo. We performed single-cell RNA and ...

Epiregulin is a dendritic cell–derived EGFR ligand that maintains skin and lung fibrosis Epiregulin is an EGFR ligand produced by DC3 dendritic cells that is essential for persistence of skin and lung fibrosis.