Wise Laboratory of Environmental and Genetic Toxicology

Wise Laboratory of Environmental and Genetic Toxicology The Laboratory uses novel cell culture models and state-of-the-art molecular and toxicological techniques to study human and marine mammal health.

Our mission is accomplished through the pursuit of the following general objectives:

Conduct innovative and multidisciplinary research in toxicology and molecular epidemiology to further our understanding of disease in humans and marine organisms, particularly as they relate to cancer, asthma and reproductive/developmental effects. Discover the mechanisms used by metals to turn normal cells into tumor cells, particularly as they relate to genomic instability and DNA repair. Establish new cell culture models from lung, skin, te**is and o***y to investigate how metals and particulates cause cancer, asthma and reproductive/developmental effects in humans and marine organisms. Study and compare contaminant-induced DNA damage and repair in models of humans and marine organisms. Determine how environmental contaminant exposure may affect the recovery of critically endangered species including marine mammals, turtles and birds. Investigate how marine pollution may impact the health of marine invertebrates such as lobsters, oysters, and corals. Create a national resource and repository of marine cell lines and tissues.

09/05/2024

Dr. John Wise, Sr., Director of the Wise Laboratory of Environmental and Genetic Toxicology, was featured in the National Institute of Environmental Health Sciences Environmental Factor for his groundbreaking research on chromium exposure across species. While humans face DNA damage and cancer risks, whales appear to recover, offering new insights into cancer prevention.🐳
Read the full article: https://factor.niehs.nih.gov/2024/9/feature/3-feature-river

"Creativity is Intelligence Having Fun" - Albert EinsteinPhoto from Wise Lab Member Haiyan Lu
06/18/2024

"Creativity is Intelligence Having Fun" - Albert Einstein

Photo from Wise Lab Member Haiyan Lu

Annual Wise Lab Dumpling Party 🥟 🎊!!
05/20/2024

Annual Wise Lab Dumpling Party 🥟 🎊!!

Congratulations to Aggie Williams, one of our Wise Lab members. She was selected as a scholar for the 2024 Scientist Men...
05/02/2024

Congratulations to Aggie Williams, one of our Wise Lab members. She was selected as a scholar for the 2024 Scientist Mentoring & Diversity Program (SMDP). SMDP is a year-long mentoring program that aims to promote mentorship and support for underrepresented groups. She will get to spend a week in San Diego, California where she will be paired with an industry mentor for a professional development training experience.

We would also like to congratulate Dr. James Wise for receiving the prestigious Metals Specialty Section Bruce A. Fowler...
03/15/2024

We would also like to congratulate Dr. James Wise for receiving the prestigious Metals Specialty Section Bruce A. Fowler Metals Young Investigator Endowment Fund Award at this years annual Society of Toxicology (SOT) meeting in Salt Lake City! Congratulations James! 🎉

Wise Laboratory members had their research efforts recognized this year with a total of 7 awards at the Society of Toxic...
03/15/2024

Wise Laboratory members had their research efforts recognized this year with a total of 7 awards at the Society of Toxicology (SOT) annual meeting in Salt Lake! 🎉 Congratulations to all! Details on the award winners are below👇

A. CSS Dharm V. Singh Carcinogenesis Graduate Student Endowment Award

3rd place - Aggie Williams

B. Environmental Carcinogenesis Merit Award for Graduate Students

Winner - Idoia Meaza

C. Environmental Carcinogenesis Merit Award for Postdoctoral Researchers

Winner - Haiyan Lu

D. Carcinogenesis Specialty Section Young Investigator Award

Winner - Jamie Young Wise

E. James A. Swenberg Carcinogenesis Merit Award for Junior Faculty Members

Winner - Sandra S. Wise

F. Mechanisms Specialty Sections Sheldon D. Murphy Student and Postdoctoral Endowment Award. Winner Idoia Meaza

G. American Association of Chinese in Toxicology. Innostar Best Abstract Award

3rd place - Haiyan Lu

For all of you not attending SOT, it’s your turn! It’s time for you to step outside the street light and help us discove...
03/11/2024

For all of you not attending SOT, it’s your turn! It’s time for you to step outside the street light and help us discover something new! Watch and share this amazing video about WHO we are, WHAT we do and HOW we do it!

Diving into the depths of environmental health, the Wise Laboratory stands at the forefront of groundbreaking research, unraveling the complex interactions b...

Hey all of you amazing toxicologists attending - make sure you check out the SOT TV monitors to see a great video abou...
03/10/2024

Hey all of you amazing toxicologists attending - make sure you check out the SOT TV monitors to see a great video about The Wise Laboratory of Environmental and Genetic Toxicology! Trust us, you will ‘whaley’ 🐋 like it! 🤩 See you later alligators! 🐊

Wise Lab Graduate student, Idoia Meaza received a prestigious two-year fellowship from the ”la Caixa” Foundation, which ...
03/06/2024

Wise Lab Graduate student, Idoia Meaza received a prestigious two-year fellowship from the ”la Caixa” Foundation, which grants 100 fellowships to Spanish or Portuguese candidates to pursue a master’s or a doctoral degree in Humanities and Art, Social Sciences, Life Sciences, Physics, Mathematics or Engineering. Idoia was 1 of only 19 students awarded a fellowship in the category of Life Sciences. Congratulations Idoia!! 🎉

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Muhammad Ali Boulevard
Louisville, KY
40292

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