Shiley-Marcos Alzheimer's Disease Research Center at UC San Diego

As you have heard, the proposed changes to Proposition 1 are threatening to cut vital programs that older adults and family caregivers depend on every day, and the BHSA Integrated Plan does not account for these devastating losses. So, we need your help!

Watch this short video message to understand what's at stake and what it means for our most vulnerable community members. Then, Take Action: contact your legislators TODAY and urge them to protect these essential services before it's too late. Go to www.caregivercenter.org/help to find out how.
Dear caregivers!
We stand in support of our partners at Southern Caregiver Resource Center and are asking you to send a message to your State Representatives in support of this important initiative. The process takes less than five minutes, and participation can make a meaningful impact at the State and local level.

We strongly encourage you to not only participate yourself, but also encourage your family members, friends, colleagues, clients, and others in your network to urge their State Representatives to take action. With a short timeframe for action, every message, and every share matters!

Today's Caring Through the Last Chapter Educational Event in partnership with Southern Caregiver Resource Center was a great success! The expertise and resources provided to attendees were practical and actionable. The recorded presentations will be posted to our YouTube channel soon!

New on UCSD-TV: Alzheimer's and Other Neurodegenerative Diseases: From Mechanisms to (Faltering) Therapies - Shiley Endowed Lecture
Visit UCSD TV to view the content on How Alzheimer's Develops
https://www.ucsd.tv/search-details.aspx?showID=41250
Alzheimer’s disease unfolds over many years through a complex interplay of amyloid, tau, genetics, lipid biology, and the brain’s immune response. John Hardy, Ph.D., explains how rare inherited forms of Alzheimer’s disease helped shape current thinking about how the disease begins, then connects those discoveries to broader questions about late onset disease and why it develops differently across people. Hardy shows that amyloid and tau are linked but not identical, and argues that problems with protein buildup and clearance both matter in understanding the disease. He also emphasizes that Alzheimer’s is not a single event but a long process, which makes prediction, diagnosis, and treatment especially difficult. While current amyloid-targeting therapies can help and show measurable benefit, Hardy says they do not stop the disease, underscoring the need for earlier diagnosis, better treatments, and wider access to care.

Watch UCSD-TV in San Diego on Cox Ch. 135.

Whether you’re currently a caregiver, professional, or planning ahead for the future - this is a can’t-miss event!

Join us for a FREE in-person Conference “Caregiving Through the Last Chapter” Co-hosted by SCRC and UC San Diego - SMADRC featuring expert speakers from local organizations discussing end-of-life preparation topics such as relevant healthcare documents, legal documents and funeral planning.

When and where? May 13th – Good Samaritan Episcopal Church – Roetter Hall
Spots are filling fast! To learn more and to secure your spot: www.caregivercenter.org/workshop

Centro de Investigación de la Enfermedad de Alzheimer Shiley-Marcos mayo 2026 -

Centro de Investigación de la Enfermedad de Alzheimer Shiley-Marcos mayo 2026 En honor al Mes de los Adultos Mayores, destacamos la importancia de comprender la salud cerebral a medida que envejecemos. La demencia no es una sola enfermedad, sino un término que describe una variedad de condiciones que afectan la memoria, el pensamiento y el funcionamiento diario. En el artíc...

UCSD Shiley-Marcos Alzheimer's Disease Research Center- May 2026 -

UCSD Shiley-Marcos Alzheimer's Disease Research Center- May 2026 In honor of Older Americans Month, we’re highlighting the importance of understanding brain health as we age. Dementia is not a single disease, but a term that describes a range of conditions affecting memory, thinking, and daily functioning. In this month’s educational feature, we explore the d...

https://tritongivingday.ucsd.edu/campaigns/shiley-marcos-alzheimers-disease-research-center

Shiley-Marcos Alzheimer's Disease Research Center - UC San Diego Giving Day At the Shiley-Marcos Alzheimer's Disease Research Center (SMADRC), physicians and scientists are advancing the frontiers of Alzheimer's disease research, working to uncover its causes, improve diagnostic precision, develop preventive strategies and ultimately discover effective treatments and a cure...

🧠 Article of the Week Spotlight

Recruiting the right participants is key to advancing Alzheimer’s research, and this week’s featured article dives into how to better reach older women at higher risk of Alzheimer’s disease.

Led by Sarah J. Banks at UC San Diego, this study explores preliminary recruitment strategies** to improve participation and representation in research, an essential step toward more effective prevention and treatment.

✨ Understanding who we reach in research shapes what we discover.

🔗 Read the full article here:
[https://www.researchgate.net/publication/399012109_Evaluating_Preliminary_Recruitment_Strategies_for_Research_Studies_in_Older_Women_at_Higher_Risk_of_AD](https://www.researchgate.net/publication/399012109_Evaluating_Preliminary_Recruitment_Strategies_for_Research_Studies_in_Older_Women_at_Higher_Risk_of_AD)

🧠 Article of the Week Spotlight**

How do we better measure change in early Alzheimer’s disease? This week’s featured study highlights the validation of a novel cognitive-functional outcome measure using data from the VIVA-MIND clinical trial.

Led by Diane Jacobs and colleagues at UC San Diego, the research shows that this composite measure may be more sensitive to cognitive decline than traditional tools potentially improving clinical trial efficiency and reducing required sample sizes.

✨ Advancing how we measure change means accelerating progress toward effective treatments.

🔗 Read the full article here:
[https://www.researchgate.net/publication/402119030_Validation_of_a_novel_cognitive-functional_outcome_measure_optimized_for_early_Alzheimer's_Disease_Evidence_from_the_VIVA-MIND_trial](https://www.researchgate.net/publication/402119030_Validation_of_a_novel_cognitive