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Alcohol exposure alters endocannabinoid levels in different brain regions. What are the health implications?

Alcoholism and the Endocannabinoid System Scientists have only recently begun to investigate and understand the critical role that the endocannabinoid system plays in alcohol addiction and various mood disorders. Alcohol dependence is linked to down-regulation of endocannabinoids and CB1 brain receptors.

As of January 1, 2021, the United States cannabis industry supported 321,000 full time jobs. Analysts predict that the industry will generate another 340,000 full-time ma*****na jobs by 2022.

Those numbers don’t even include the black market cannabis industry, which is valued at roughly $64 billion. As more states legalize ma*****na, thousands of black market jobs will move to the legal w**d industry.

What does this mean for aspiring ma*****na industry employees? It means that there’s never been a better time to start a legitimate career in the thriving legal cannabis industry!

https://cannabistraininguniversity.com/blog/ma*****na-jobs/cannabis-careers/?utm_source=ActiveCampaign&utm_medium=email&utm_content=Have+You+Seen+the+Top+Cannabis+Careers+2021-2022%3F&utm_campaign=Top+Cannabis+Career+2021+2022

Unfortunately, there is no standard in the industry for categorizing cannabis quality. So, the problem is...low quality w**d is everywhere!

To have the best cannabis experience, you need to know how to identify high-quality w**d and then know the best ways to consume it.

If you want some extra guidance about what cannabis elements to be looking for in your perfect bud, and how those features can help elevate your overall cannabis experience, then don't miss your opportunity to attend this course on becoming a "Professional Bud Examiner & Consumer" - https://trichomeinstitute.com/go/csmith/

Interested in being your own boss? Cannabis is the fastest-growing industry in the U.S., according to a 2021 Leafly Jobs Report. The spread of cannabis legalization means there are many business opportunities for budding entrepreneurs. Gain the advantage by following up with our Cannabiz expert Ceally Smith at ceallysmith.com

5 Ways to be a More Conscious Cannabis Consumer

1. Shop at Companies That Support Local or Small Farmers

Farm-to-table has become a grocery store standard by providing customers the best quality foods and vegetables directly from nearby farmers. In the cannabis industry, this not only allows for organically-produced cannabis, but it also supports local growers that are often struggling with big corporations.

More states are legalizing medical and recreational use, and that’s fantastic! Greed, however, isn’t great. But quality over quantity is the motto for local growers. Consumers can ask the budtenders at their local dispensary about their policies on supporting small farmers.

2. Find a Company Whose Values Align with Yours

Many organizations have their mission statements and values stated proudly on their website. From supporting legacy farmers and nonprofits to donating proceeds to charity, consumers can buy from companies that best align with them.

Never compromise one’s values for w**d. The industry has tons of dispensaries that support local businesses, give back to the community, and are committed to equitable social causes. The industry may be growing, but its past is still showing. For example, according to the Last Prisoner Project, there are 40,000 people incarcerated for cannabis-related crimes; many of them are Black men.

Nonprofits such as the Last Prisoner Project have a page dedicated to its ambassadors, corporate sponsors, and donations by time or money. Customers can contact their local dispensary for more information about the companies and nonprofits they support.

3. Zero Waste and Recycling Programs

Zero Waste stores are here, and they’re thriving. They may be for food and body products, but dispensaries implement these ideas for a waste-free environment, too. Curaleaf, a dispensary in New York, for example, gives its consumers a reusable bag on their first visit. If they bring the bag back, they get a discount. Who doesn’t like a bargain! Discounts encourage low waste to pave the way for zero waste.

Additionally, TerraCycle — a waste management company — has Cannabis Packaging Zero Waste Boxes available for purchase. On TerraCycles website, they “created a zero waste solution for used and empty cannabis packaging purchased from licensed retailers.” Dispensaries collect the recyclable material that is then shipped off and recycled into new plastic. Customers can ask the budtenders if their dispensary is a part of this program, or encourage them to join similar efforts.

4. Support Businesses Owned by People of Color

The American Civil Liberties Union (ACLU) highlights that Black people are four times more likely to be arrested for cannabis. The Latinx community is also at a higher risk of incarceration. While it’s good to support small businesses, the majority of them are owned by white men.

Whether it’s an edibles company or a dispensary, supporting businesses owned by people of color is essential. Small contributions give to the community that is impacted most by over-policing and high incarceration rates.

Ensure purchases support equity business. There are several resources, including online directories, in the cannabis industry and beyond, that spotlight minority-owned businesses. For example, Emerald’s Conscious Consumption Series highlights more than 400 Black, Latinx, Indigenous and Asian-owned cannabis companies.

5. Support Sustainable and Environmentally-Friendly Practices

Another option for consumers is to support companies that use sustainable packaging. For example, one company that provides such packaging for the cannabis industry is HiSierra. HiSierra creates kid-safe alternatives from sugarcane fibers.

HiSierra isn’t the only company using sustainable packaging, Sana Packaging, Sun Grown Packaging, and FunkSac have all implemented child-proof, eco-friendly containers, according to Pretty Lethal Designs. Consumers can find out more information by going directly to their websites to support them.

Change doesn’t happen overnight. But remaining conscious about one’s consumption habits over time can decrease environmental footprints and increase awareness. Changing the way one consumes cannabis can translate to other daily sectors.

CeallySmith.com

The CDC estimates that 1 in every 54 children in the U.S. has autism.

It can significantly hinder a person’s social, communicative, and behavioral development starting from a young age.

Some children develop symptoms within the first few months of life.

Anecdotal evidence supports the use of cannabis in treating symptoms. The long-term effects of THC on the developing brain are controversial, so high-CBD/low-THC strains are preferred, unless the case is palliative.

Cannabis for Autism: What Research Says...

Research into cannabis and autism spectrum disorders is still new. In 2018, a Stanford University study found that anandamide levels (the bliss molecule) was lower in children with ASD. Some research suggests that THC produces more intense and similar effects to anandamide. In theory, THC could be a promising option for autism patients.

A study published in 2019 in the Journal of Nature found that cannabis can relieve symptoms of autism such as seizures, restlessness, cognitive impairment, speech impairment, and fits of rage. The study was titled “Real life experience of medical cannabis treatment in autism; analysis of safety and efficacy.”

In this study, 188 patients with autism spectrum disorder were followed up over six months. Most patients were treated with a cannabis oil containing 30% CBD and 1.5% THC.

After six months of treatment, 82.4% of patients were in active treatment and 60.0% have been assessed. Here are the results of the study:

•1% of patients reported improvement in symptoms
•7% reported moderate improvement
•4% of patients reported slight improvement
•6% reported no change in condition
•About 25% of patients experienced at least 1 side effect from the treatment (the most common was restlessness)

Overall, cannabis was found to be a “well tolerated, safe, and effective option to relieve symptoms associated with ASD.”

A 2018 study performed at the Shaare Zedek Medical Center tested the effect of a whole-plant cannabis extract (20:1 CBD:THC) on 60 autistic children who displayed severe behavioral issues. Here are the results:

Behavioral outbreaks were much improved or very much improved in 61% of patients

Anxiety and communication issues were much or very much improved in 39% and 47%, respectively

Disruptive behaviors were improved by 29%

Parents reported lower stress levels, by 33%

Adverse effects included sleep disturbances (14%), irritability (9%), and loss of appetite (9%)
In a study published in 2018 titled “Oral Cannabidiol Use in Children With Autism Spectrum Disorder to Treat Related Symptoms and Co-morbidities,” 53 children with autism were given a dose of 20:1 ratio of CBD to THC for a period of 66 days.

Self-injury and rage attacks improved in 67.6% and worsened 8.8%

Hyperactivity symptoms improved in 68.4%, did not change in 28.9% and worsened in 2.%

Sleep problems improved in 71.4% and worsened in 4.7%

Anxiety improved in 47.1% and worsened in 23.5%

Adverse effects were primarily mild drowsiness and loss of appetite

Keep in mind, studies into autism and cannabis have been focused on observational results without a control group. Results were based on reports by parents, which may have been affected by expectations.

Trials into autism and cannabis are underway by the Children’s Hospital of Philadelphia, the University of San Diego, and New York University’s Langone Health research facility.

Best Ways to Consume Cannabis for Autism:
There is a lot of anecdotal evidence to suggest that treating autism with medical cannabis is effective. However, not every method of administration is good for children. For instance, inhalation such as smoking cannabis is not suggested due to the carcinogens present in the smoke.

Instead, medical cannabis can be administered in the following ways:

•Edibles: Cannabis infused foods and drinks can provide long-lasting effects. While the onset of effects can take between one or two hours, the effects can last for about six to eight hours, a considerable increase compared to other methods of consumption.

•Tinctures: Tinctures such as THC and/or CBD oils can be used to infuse foods with cannabis or applied sublingually (under the tongue). Sublingual absorption provides a quicker onset of effects (10 to 15 minutes) since the compounds absorb through mucous membranes under the tongue.

•Va**ng: Va**ng is a less irritating method of consumption compared to smoking cannabis. V**e products produce a cannabis v***r instead of smoke, which can provide a fast onset of effects within minutes.

Choosing the best way to administer cannabis can take some time. It is recommended to start with the lowest dose possible (2.5 to 5 mg) of cannabis and gradually build up to the desired effects.

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Will we someday have h**p batteries powering our vehicles?

Learn how h**p batteries are made and what role they might play in the future

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Is h**p plastic an alternative solution that could allow us to enjoy the modern-day advantages of plastic, while still protecting our planet?

Plastic is everywhere. It’s in the smartphones in our pockets, the cars we drive, the packaging of consumer goods, and the jet planes that streak across the sky. Plastic helps the world run, but it’s also leaving a devastating impact on the environment as it piles up in landfills or finds its way into the ocean. Is h**p plastic an alternative solution that can allow us to keep enjoying plastic while protecting our planet?

CeallySmith.com

What are cannabinoids?

Cannabinoids are a class of lipophilic molecules that interact with the body's endocannabinoid system (ECS).

The ECS helps the body maintain functional balance through its three main components: “messenger” molecules that our bodies synthesize, the receptors these molecules bind to, and the enzymes that break them down.

Pain, stress, appetite, energy metabolism, cardiovascular function, reward and motivation, reproduction, and sleep are just a few of the body's functions that cannabinoids impact by acting on the ECS.

The potential health benefits of cannabinoids are numerous and include inflammation reduction and nausea control.