Developmental Studies Hybridoma Bank

Our mission is to provide the basic research community with hybridomas and monoclonal antibodies of the highest quality at the lowest prices.

The DSHB was created in 1986 by the Institute of Child Health and Human Development (NIH) to bank and distribute hybridomas and the monoclonal antibodies (MAbs) they produce to the general scientific community in order to facilitate research. Our first intention was, and still is, to keep the prices low so that researchers can test multiple MAbs without commitment of significant funds, then contin

03/17/2026

Spotted in Neuropsychopharmacology!
Researchers from Northeastern University, among others, used DSHB's anti-β-tubulin [E7] mAb in a study on how adolescent psilocybin exposure leads to sex‑dependent changes in brain development in mice.

📄 https://tinyurl.com/33ts3bcn

🧫 https://dshb.biology.uiowa.edu/E7_2

03/16/2026

Spotted in PLOS Genetics!
Researchers from The Institute of Genetics at HUN-REN Biological Research Centre used DSHB's anti-enabled [5G2] (magenta) and anti-hts [hts RC] mAbs in a study on how two distinct actin networks position the nucleus in Drosophila nurse cells during egg development.

📄 https://tinyurl.com/yrpje734

🧫 https://dshb.biology.uiowa.edu/5G2-anti-enabled
🧫 https://dshb.biology.uiowa.edu/hts-RC

03/11/2026

That's a wrap on Dros26! 🪰

Thank you to everyone who stopped by the DSHB booth—we loved hearing about the antibodies you’re using and the reagents on your wishlists.

📸 Drosophila larva labeled with DSHB anti-slit (red)
🧫 https://dshb.biology.uiowa.edu/C555-6D

03/07/2026

Dros26 Day 3

Did you know DSHB houses over 1600 Drosophila antibodies?

Browse the collection and more: https://dshb.biology.uiowa.edu/

📸 Drosophila germarium labeled with DSHB anti-Vasa (green) and anti-hts (magenta)

🧫 https://dshb.biology.uiowa.edu/anti-vasa
🧫 https://dshb.biology.uiowa.edu/1B1

03/06/2026

Dros26 Day 2

What antibodies do you wish we had? Comment below your antibody wishlist!

📸 Drosophila egg chamber labeled with DSHB anti-hts in yellow
🧫 https://dshb.biology.uiowa.edu/hts-RC

03/05/2026

Dros26 Day 1

Comment below your favorite DSHB antibody!

📸 Drosophila brain labeled with DSHB anti-Bruchpilot in blue
🧫 https://dshb.biology.uiowa.edu/nc82

03/05/2026

Come check out our booth at Dros26!

02/20/2026

🔎 Spotted in PLOS Genetics!
Researchers from Hefei University of Technology, among others, used DSHB's anti-DE-Cadherin [DCAD2], anti-beta-galactosidase [40-1a], and anti-EZH2 [PCRP-EZH2-1B3] mAbs in a study on how excess iron drives tumor growth and invasiveness in a Drosophila cancer model.

📄 https://tinyurl.com/3x584u3u

🧫 https://dshb.biology.uiowa.edu/DCAD2
🧫 https://dshb.biology.uiowa.edu/40-1a
🧫 https://dshb.biology.uiowa.edu/PCRP-EZH2-1B3

02/18/2026

🔎 Spotted in Neurobiology of Disease!
Researchers from Ohio State University and Wright State University Boonshoft School of Medicine used DSHB's anti-NF-M [2H3] and anti-SV2A mAbs in a study on a new SCN8A epileptic encephalopathy mouse model that depicts seizures and motor impairments seen in patients.

📄 https://tinyurl.com/49z3nsuj

🧫 https://dshb.biology.uiowa.edu/2H3
🧫 https://dshb.biology.uiowa.edu/SV2

02/16/2026

🔎 Spotted in Cell!
Researchers from RIKEN Center for Brain Science used DSHB's anti-brp [nc82] mAb in a study on how a mobile uORF‑encoded peptide (USIC) triggers systemic stomatal immunity in plants.

📄 https://tinyurl.com/ynrmtrw8

🧫 https://dshb.biology.uiowa.edu/nc82

02/09/2026

🔎 Spotted in Fish Physiology and Biochemistry!
Researchers from National Chung Hsing University and National Cheng Kung University used DSHB's anti-α5 mAb in a study on salinity‑dependent ion‑regulatory responses to acute cold stress in Indian medaka.

📄 tinyurl.com/funjkkwv

🧫 dshb.biology.uiowa.edu/a5

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Location

Iowa City

Telephone

+13193353826

Website

http://dshb.biology.uiowa.edu/

Address

210 East Iowa Avenue
Iowa City, IA
52242

Opening Hours

Monday	8am - 5pm
Tuesday	8am - 5pm
Wednesday	8am - 5pm
Thursday	8am - 5pm
Friday	8am - 5pm