09/21/2026
HAVE YOU GONE DOWN THE PHOSPHATIDYLCHOLINE RABBIT HOLE YET? šš§¬
If you're anything like me, once you start researching mitochondrial dysfunction, methylation, neurodevelopment, and all the biological processes involved in brain and nervous system function, you quickly realize that there is SO much more to learn.
And one of the things that has become particularly interesting to me throughout our journey is phosphatidylcholine.
We spend a lot of time talking about supplements that support mitochondrial function, neurotransmitters, methylation, gut health, and other biochemical processes.
But what about the actual STRUCTURE of our cells?
Every single cell in our body is surrounded by a membrane made largely of phospholipids.
These membranes are responsible for helping regulate what enters and leaves the cell, maintaining cellular structure, and supporting communication between cells.
Our mitochondria even have their own specialized membranes that are essential for normal cellular energy production.
One of the major phospholipids in the body is phosphatidylcholine.
Phosphatidylcholine is involved in several important biological functions:
BRAIN & NERVOUS SYSTEM- Phospholipids are structural components of neuronal membranes. Phosphatidylcholine also provides a source of choline, which the body uses to produce acetylcholine, a neurotransmitter involved in muscle activation, attention, memory, and autonomic nervous system signaling.
MITOCHONDRIAL FUNCTION- Mitochondria have specialized inner and outer membranes that contain phospholipids. These membranes are essential for maintaining mitochondrial structure and supporting the processes involved in ATP production.
CELLULAR COMMUNICATION- Cell membranes do much more than separate the inside of a cell from its environment. They contain receptors, proteins, and signaling molecules that allow cells to receive information and respond to changes in their environment.
LIVER FUNCTION- phosphatidylcholine is involved in packaging and transporting fats, including the formation of lipoproteins that help move triglycerides out of the liver.
AND THEN THERE'S METHYLATION...
This is where things get especially interesting if you've spent time researching MTHFR, PEMT, choline metabolism, and folate pathways.
Your body can produce phosphatidylcholine through a pathway called PEMT, which uses methyl groups.
Your body can also produce PC through the CDP-choline pathway, which uses choline.
Meanwhile, choline can be converted into betaine, which participates in an alternative pathway for recycling homocysteine into methionine.
This is why choline metabolism, PC synthesis, and methylation are so interconnected!
It's also important to understand that supplementing PC isn't the same thing as directly correcting a methylation problem or replacing folate or B12.
The more I learn about all of these pathways, the more interested I become in looking at how our cells are built and how all these different systems work together.
And this is one of the reasons I've become such a fan of PC!
Their full-spectrum phospholipid complex contains phosphatidylcholine (PC), phosphatidylethanolamine (PE), and phosphatidylinositol (PI).
These phospholipids play important roles in cellular membrane structure, flexibility, and signaling.
I've spent so much time learning about mitochondrial function, neuroplasticity, neurodevelopment, and methylation throughout our autism journey, and understanding phospholipids has added another interesting piece to that puzzle.
BodyBio is having a rare TWO-DAY FLASH SALE! Tuesday, September 22nd & Wednesday, September 23rd ONLY!
š 25% OFF BodyBio PC
š NO CODE NEEDED! The discount automatically applies at checkout.
If you've been wanting to try BodyBio PC or need to restock, this is a great opportunity to save!
SHOP THROUGH MY AFFILIATE LINK: https://bodybio.com/WAKEUPWELLNESS
I'll also put the link in the comments and in my bio! š
*Affiliate disclosure: I am a BodyBio affiliate and may earn a commission when you purchase through my link, at no additional cost to you. I'm sharing our personal experience and educational information about phospholipids. This is not medical advice.*
