Ohio Supercomputer Center

🦎 A handful of lizards brought to Ohio from Italy in the 1950s sparked a decades-long biological mystery.

New research from Ohio Wesleyan University, the University of Cincinnati, and The Ohio State University examined how Ohio’s now-famous wall lizards overcame a severe genetic bottleneck and successfully established themselves in a new environment. The findings provide new insight into adaptation, evolution, and population genetics.

Behind the scenes, researchers from the three institutions worked together to process and analyze genomic data using the Ohio Supercomputer Center, demonstrating how Ohio's unique high performance computing solution supports discoveries across the life sciences and enables collaboration across campus boundaries and categories.

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Wall lizards in Ohio reproduced their way out of a genetic bottleneck Non-native wall lizards living in Cincinnati, Ohio, have thrived against the odds thanks to an ability to expand their population more quickly than any inbreeding-amplified harmful genes could weaken their chances for survival, new research suggests. An estimated 10 of these European common wall li...

We were saddened to learn this week of the passing of Russell M. Pitzer, a co-founder and guiding force behind the Ohio Supercomputer Center. Russ helped shape the Center in its earliest days and remained involved for decades.

In 2018, OSC named a state-of-the-art supercomputer cluster in his honor. Just as the Pitzer cluster continues to power research and discovery, Russ’s impact will continue to be felt across Ohio for years to come. We extend our condolences to his family, friends, and colleagues.

https://www.ohiocremation.org/obituaries/Russell-Pitzer?obId=48535292 #/obituaryInfo

From molecular machine learning to mathematical modeling tied to heart rhythm research, Ohio University students and researchers are leveraging the Ohio Supercomputer Center to take on increasingly complex, data-intensive work.

As manager of software engineering within Ohio University’s Central IT department and product manager for research computing, Robert Foreman works closely with faculty and students to connect them with advanced computing resources through OSC.

“If you have HPC needs, OSC should be your first stop,” Foreman said.

As a shared statewide resource, OSC helps expand research opportunities, support student learning, and provide hands-on experience with the types of computing environments students may encounter in research and industry careers.

Learn how Ohio University is preparing students and researchers to work at scale with advanced computing resources:

Ohio University researchers turn to Ohio Supercomputer Center as computing demands grow At Ohio University, students and researchers are using the Ohio Supercomputer Center (OSC) to take on increasingly complex, data-intensive work—from simulating medical research problems to creating digital art with artificial intelligence. For Robert Foreman, Ohio University’s Campus Champion fo...

Across the Midwest, faculty and students are exploring how artificial intelligence can be meaningfully integrated into research and the classroom.

At the NSF ACCESS Regional Workshop on AI, hosted by the Ohio Supercomputer Center, nearly 100 participants came together to share approaches, challenges, and emerging best practices — from building campus AI services to addressing questions around ethics, privacy, and implementation.

Keynotes from Ayanna Howard and Timothy Huerta highlighted an important theme: AI should support human decision-making, not replace it.

The workshop also connected attendees with national resources like NSF ACCESS and the National AI Research Resource (NAIRR), helping institutions better understand how to access tools, funding, and support for AI-driven work.

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Midwest academics share AI innovations for research, teaching at OSC-hosted event Across the United States, higher education institutions are navigating the rapidly evolving artificial intelligence (AI) landscape, as faculty and students assess how to effectively incorporate machine learning, data analytics, large language models, and other AI tools into their classroom instructi...

🤝 Great to be part of Ohio State’s Stronger Together IT Conference.

During our session, Enhancing Collaboration and File Sharing with Globus, we explored how OSC is helping research teams securely move and share large datasets, streamline workflows, and collaborate more effectively across institutions.

From reducing friction in data transfer to enabling scalable, reliable access to research data, these tools are helping teams spend more time on discovery and less time managing infrastructure.

Thank you to everyone who joined the session and contributed to the discussion — we appreciated the thoughtful questions and conversations.

New research from The Ohio State University College of Medicine, in collaboration with the Georgia Institute of Technology, offers some of the clearest views yet of a DNA repair protein linked to BRCA-related cancer risk.

The study provides new insight into how damaged DNA is identified and repaired — a critical process in understanding and potentially treating cancer.

Behind the scenes, data from this work were processed on the Ohio Supercomputer Center, highlighting how high performance computing enables this complex biomedical research.

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Best snapshots yet of DNA repair protein relevant to BRCA mutations Scientists have captured the most detailed structural images to date of a specific type of protein’s DNA repair process, a finding that could reveal ways to inhibit the effects of BRCA1 and BRCA2 mutations that heighten the risk for breast, ovarian and other cancers. Previous research has shown t...