06/21/2026
A Self-Immunoregulatory Nanosensitizer for Sonodynamic Cancer Therapy – Research
Sonodynamic therapy (SDT) generates reactive oxygen species (ROS) for noninvasive, spatiotemporally controlled tumor therapy. However, whether ROS-driven stress also reprograms tumor immune signaling toward immune resistance, thereby limiting durable antitumor immunity, remains unclear. This study reveals that immune resistance is a universal mechanism shared by three major classes of clinically used SDT sensitizers. A porphyrin-biguanide-loaded albumin nanoparticle (POR-BG@Alb) is rationally developed as a self-immunoregulatory sonosensitizer, which induces mitochondrial dysfunction to activate AMP-activated protein kinase (AMPK) and suppress c-MYC, concomitantly downregulating PD-L1 and CD47 and enhancing T-cell killing and macrophage phagocytosis....
A Self-Immunoregulatory Nanosensitizer for Sonodynamic Cancer Therapy – Research
Sonodynamic therapy (SDT) generates reactive oxygen species (ROS) for noninvasive, spatiotemporally controlled tumor therapy. However, whether ROS-driven stress also reprograms tumor immune signali…
06/21/2026
NIMS Postdoctoral Researcher job with National Institute for Materials Science (NIMS) – (Jobs)
Job Details You will be engaged in the research and development of functional polymer materials, such as adhesive, self-healing, and recycling polymers. We welcome those who are interested in data-driven research and automated or autonomous experiments. Experience in polymer synthesis, polymer structure analysis, or physical property analysis is preferred.
Applicant should (or is expected to) have a Ph.D. degree in the field of chemistry....
NIMS Postdoctoral Researcher job with National Institute for Materials Science (NIMS) – (Jobs)
Job Details You will be engaged in the research and development of functional polymer materials, such as adhesive, self-healing, and recycling polymers. We welcome those who are interested in data-…
06/21/2026
Why Telangana doctors are opposing proposal to raise medical faculty retirement age to 70 – NewsMeter – Open Positions
Why Telangana doctors are opposing proposal to raise medical faculty retirement age to 70 NewsMeter Read more about his post... Credits: Source Disclaimer
Why Telangana doctors are opposing proposal to raise medical faculty retirement age to 70 – NewsMeter – Open Positions
Why Telangana doctors are opposing proposal to raise medical faculty retirement age to 70 NewsMeter Read more about his post… Credits: Source Disclaimer
06/20/2026
Scientists Finally Uncover Why Solid-State Batteries Short-Circuit – Science News
A new study sheds light on one of the biggest obstacles preventing the widespread adoption of solid-state batteries. Credit: Stock Researchers have uncovered a critical mechanism behind battery failure in solid-state batteries, offering new insights that could help unlock safer, longer-lasting energy storage technologies. Every time a smartphone is charged or an electric vehicle is plugged in, billions of lithium ions move through a battery to store energy....
Scientists Finally Uncover Why Solid-State Batteries Short-Circuit – Science News
A new study sheds light on one of the biggest obstacles preventing the widespread adoption of solid-state batteries. Credit: StockResearchers have uncovered a critical mechanism behind battery fail…
