Human Behavioral Pharmacology Lab

Human Behavioral Pharmacology Lab We investigate the effects of alcohol and recreational drugs in human volunteers. All research subjects are paid for their participation.

Under the direction of professor Harriet de Wit, the Human Behavioral Pharmacology Laboratory (HBPL) investigates the determinants and the consequences of drug and alcohol use by measuring physiological, behavioral and subjective effects of acute doses of psychoactive drugs in human volunteers. We are always looking for new participants between the ages of 18 and 35 to participate in our studies.

Different studies require different amounts of time, and pay different amounts of money. All of our studies are conducted at the University of Chicago in Hyde Park. We are currently looking for subjects with any of the following qualifications:

- Moderate to heavy drinkers
- Club drug users
- Recreational drug users
- Light smokers or non-smokers

In order to see which, if any, of our studies you may qualify for we need you to provide us with some preliminary information. The easiest way to do this is to complete our online questionnaire. http://tinyurl.com/dewitlab

Please fill it out as honestly and accurately as possible. All of the information you disclose on the questionnaire is confidential. Once you submit a questionnaire, we will review your responses and send you information on whichever studies you potentially qualify for. Please note that this review may take up to a week. In the event that there are no studies that match your qualifications, it is our policy not to disclose why. Please note that, in order to participate, we will need you to come into the lab at least three times total, and at least twice (for at least 2 hours) during normal business hours. If you are certain you will not be able to make it into the lab at any time during normal business hours, we are very sorry to say that we will not be able to have you as a subject. http://psychiatry.bsd.uchicago.edu/hbpl/

We are recruiting individuals 18-35 years of age who are feeling Depressed and who are NOT on any medications currently....
08/09/2022

We are recruiting individuals 18-35 years of age who are feeling Depressed and who are NOT on any medications currently. Earn up to $195 in just 3 short visits!

Take our screening questionnaire to see if you potentially qualify!
https://is.gd/hbplsurvey

We are recruiting individuals 18-35 years of age that are feeling Depressed and are NOT on any medications currently. Ea...
07/14/2022

We are recruiting individuals 18-35 years of age that are feeling Depressed and are NOT on any medications currently. Earn up to $195 in just 3 short visits!

Take our screening questionnaire to see if you potentially qualify!

https://redcap.uchicago.edu/surveys/?s=YJYWPF4NA9

Why do healthy people choose to use d-amphetamine?Is it their personality? To “escape” a negative mood? Social pressure?...
05/12/2021

Why do healthy people choose to use d-amphetamine?

Is it their personality? To “escape” a negative mood? Social pressure? The desire for pleasure? A combination of factors?

Many previous studies reviewed by this laboratory found that experiencing pleasure or euphoria after using stimulants like d-amphetamine predicts future usage.

How does THC affect memory? We conducted a study on this important question and found a variety of interesting results. ...
02/25/2020

How does THC affect memory? We conducted a study on this important question and found a variety of interesting results. Read a quick blog post of what we found out!

Take a look here:

This article was written by Kaela Allen, an undergraduate at U of Chicago, based on M Doss, D Gallo, H de Wit (2019) D9-tetrahydrocannabinol during encoding impairs perceptual details yet spares context effects on episodic memory. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging &

Can oxytocin dampen stress-induced cigarette cravings? We conducted a study on this extremely common trigger to see. Rea...
01/21/2020

Can oxytocin dampen stress-induced cigarette cravings? We conducted a study on this extremely common trigger to see. Read a quick blog post with an overview of what we found, or rather, did not find!

Take a look at the post here:

de wit lab administrator January 21, 2020 Can oxytocin dampen stress-induced cigarette cravings? de wit lab administrator January 21, 2020 This summary, written by Autumn Mitchell, is based on an article by Van Hedger, Lee, Kushner and de Wit (2019): Effects of intranasal oxytocin on stress-induced....

What if you could predict, and possibly prevent, impulsive and addictive behaviors such as drug and alcohol addiction, b...
11/13/2019

What if you could predict, and possibly prevent, impulsive and addictive behaviors such as drug and alcohol addiction, binge eating/obesity, and problem gambling?

We conducted a study to test these questions for ourselves. Read a quick blog post with an overview of what we found!

Take a look at the post here: http://hbpl.uchicago.edu/what-are-we-doing/2019/11/13/what-if-you-could-predict-and-possibly-prevent-impulsive-and-addictive-behaviors-such-as-drug-and-alcohol-addiction-binge-eatingobesity-and-problem-gamblinghttp://hbpl.uchicago.edu/what-are-we-doing/2019/11/13/what-if-you-could-predict-and-possibly-prevent-impulsive-and-addictive-behaviors-such-as-drug-and-alcohol-addiction-binge-eatingobesity-and-problem-gambling

This summary, written by Kaela Allen, is based on a paper published from our lab (available online): Weafer, J, NA Crane, SM Gorka, KL Phan, H de Wit (2019). Neural correlates of inhibition and reward are negatively associated. NeuroImage, 196:188-194. PMID: 30974242

How does methamphetamine affect brain processing? Check it out by clicking the link below!Here at the HBPL, we want ever...
10/30/2019

How does methamphetamine affect brain processing? Check it out by clicking the link below!

Here at the HBPL, we want everyone to know and understand the type of work we are doing. That’s why we started uploading these easy-to-read summaries of our studies and findings on our website. Go and take a look at some of our previous blog posts under the “What Are We Doing?” tab.

This summary, written by Ilaria Tare, is based on a paper published from our lab and available on our website: Van Hedger, Kathryne, et al. “Effects of Methamphetamine on Neural Responses to Visual Stimuli.” Psychopharmacology , 236:1741–1748, 2019.

Could a history of hypomanic experiences potentially affect an individual's chances of developing a substance use disord...
10/09/2019

Could a history of hypomanic experiences potentially affect an individual's chances of developing a substance use disorder?

We conducted a study on young adults to see test it for ourselves. Read a quick blog post with an overview of our study and what we found!

This summary is based on a paper published from our lab and available on our website: “Subjective responses to amphetamine in young adults with previous mood elevation experiences”.

Can microdosing L*D benefit your mental health? Improvement on mood, creativity, and cognition are some of the many thin...
08/21/2019

Can microdosing L*D benefit your mental health? Improvement on mood, creativity, and cognition are some of the many things people claim it can do.

Here at the HBPL, we conducted the first placebo-controlled, double-blind study to empirically test whether or not microdosing, specifically with L*D, actually has any of the positive effects that users report.

Take a look at our second-ever blog post for more info!

de wit lab administrator August 13, 2019 Could microdosing L*D make you happier? de wit lab administrator August 13, 2019 Over the past few years the popularity and public familiarity with the concept of “microdosing” has rapidly increased. Microdosing consists of taking a low, sub-perceptual do...

Reading through long research articles can be confusing and exhausting if you don’t have a B.S or PhD in something scien...
08/07/2019

Reading through long research articles can be confusing and exhausting if you don’t have a B.S or PhD in something sciency. But, we think what we are doing IS interesting and we want to share it with you! Starting today, we will begin uploading blog posts with quick synopses of research studies we’ve done, and why they matter.

Our first post: Elisa Pabon, a fourth-year doctoral candidate in our lab, made a phone app to measure THC-induced impairment under controlled conditions.

With legalization of recreational cannabis use spreading across the nation, one question remains on many minds--how can we measure cannabis-induced impairment?

Do you feel down? Research Subjects Wanted!Participants who report feeling sad or down are needed for a brand new resear...
03/27/2019

Do you feel down? Research Subjects Wanted!

Participants who report feeling sad or down are needed for a brand new research study that has opened up for recruitment! Total payment for completing all sessions is $450 (8 sessions total in length). Fill out our survey to see if you are eligible:

Web survey powered by SurveyMonkey.com. Create your own online survey now with SurveyMonkey's expert certified FREE templates.

We've recently started up a brand new study that is now open for enrollment! See if you potentially qualify today by fil...
01/24/2019

We've recently started up a brand new study that is now open for enrollment! See if you potentially qualify today by filling out our survey. All our volunteers are compensated for their time ($150 - $450 depending on study).

Web survey powered by SurveyMonkey.com. Create your own online survey now with SurveyMonkey's expert certified FREE templates.

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5841 S Maryland Avenue
Chicago, IL
60637

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