06/03/2026
Herpes simplex keratitis and varicella zoster keratitis can look similar at first glance, but their corneal lesions have key differences that help guide diagnosis and treatment. 🔍
This graphic compares classic HSV dendrites with VZV pseudodendrites:
• HSV lesions are larger, ulcerative, stain centrally with fluorescein, and feature terminal bulbs
• VZV lesions are smaller, raised, lack terminal bulbs, and usually do not show central staining
• HSV is typically treated with topical antivirals, while VZV requires systemic antiviral therapy
Recognizing these subtle exam findings can help you quickly distinguish between two important causes of infectious keratitis in the ED and clinic setting. 👁️🩺
05/26/2026