The Proteolysis Lab at AU

03/02/2026

02/24/2026

07/10/2024

We've been thinking a lot about pseudopeptidases, enzymes that look like enzymes, but aren't enzymes. Just out, a review on this topic, in Frontiers in Molecular Biosciences!

Inactive enzyme homologs, or pseudoenzymes, are proteins, found within most enzyme families, that are incapable of performing catalysis. Rather than catalysi...

03/12/2024

Some excellent presentations

04/18/2023

Congrats to Terika Williams for a great presentation of her Honors thesis!

03/17/2023

Erica Shin and Konstantin Zubkov shared their research today at MASAL 2023. The Michigan Academy of Science, Arts, and Letters. Great presentations!

02/13/2023

A new publication just out today in Scientific Reports! The result of a lot of work by Daniel Fajardo, Ritchie Saint Jean, and Peter Lyons.

Gene duplication is a key first step in the process of expanding the functionality of a multigene family. In order to better understand the process of gene duplication and its role in the formation of new enzymes, we investigated recent duplication events in the M14 family of proteolytic enzymes. Wi...

02/10/2023

10/04/2022

https://qubeshub.org/community/groups/coursesource/publications?id=3542&v=1

Structure and function are correlated at all levels of biology. This topic is typically addressed early in an undergraduate class in general or molecular biology before students have gained much skill or knowledge in molecular biology. However, an understanding of the chemical bonds involved in f...

04/17/2022

Masy Domecillo presented her honors thesis, the work of the last almost three years, on Friday. "The role of the prodomain in the folding of carboxypeptidase A1." Excellent work, Masy!

04/05/2022

The Proteolysis Lab spent a few days attending Experimental Biology 2022 in Philadelphia. Whew! That was a lot of information!