Innovative Genomics Institute

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Innovative Genomics Institute Using genome engineering to solve humanity’s greatest problems in health, climate & sustainable agriculture. UC Berkeley, UCSF, UC Davis, UC San Diego.

innovativegenomics.org The Innovative Genomics Institute (IGI) is composed of diverse researchers with a powerful combined expertise. After the development of the CRISPR-Cas9 system for rewriting DNA, we realized the potential of applying this technology to solve some of humanity’s greatest problems. Our scientists conduct world-class research, driven by the real possibility to cure human disease, end hunger, and protect the environment. In addition to our scientific efforts, the IGI is committed to advancing public understanding of genome engineering and providing resources for the broader community.

Most neurodegenerative diseases begin with misfolded proteins. A new project funded by the Advanced Research Projects Ag...
10/09/2026

Most neurodegenerative diseases begin with misfolded proteins. A new project funded by the Advanced Research Projects Agency for Health BIOGAMI program seeks to prevent neurodegenerative diseases by learning the language of disordered proteins in human cells at scale. Learn more: https://ow.ly/5IUF50ZW7EE

ICYMI: IGI's Martin Kampmann is using to uncover the mechanisms of tau proteostasis. His team has found a novel pathwa...
10/07/2026

ICYMI: IGI's Martin Kampmann is using to uncover the mechanisms of tau proteostasis. His team has found a novel pathway to clear toxic tau buildup, which could lead to a new strategy to treat dementias like Alzheimer's disease. Read more in his Cell paper from earlier this year: https://ow.ly/GjyW50ZU3o2

The 2026 UC Regents Innovation Awards honor two of IGI's Investigators! Fyodor Urnov has been given the Gamechanger Awar...
09/28/2026

The 2026 UC Regents Innovation Awards honor two of IGI's Investigators! Fyodor Urnov has been given the Gamechanger Award for his contributions to the first personalized medicine and Sue Lynch has been given the Disruptive Research Award for her work on how the infant gut influences health outcomes later in life. Read more: https://ow.ly/BL0A50ZPgfF

Predicting how folds would be a valuable tool for scientists, but has not been able to crack the problem. A team at ...
09/24/2026

Predicting how folds would be a valuable tool for scientists, but has not been able to crack the problem. A team at the IGI made significant progress on two key hurdles: limited structural data, and the fact that RNA can take on multiple shapes. Read more:
https://ow.ly/x8JM50ZJcTZ

Pictured: coauthors Roma Nagle and Conner Langeberg

Before , there was VIPR — a tool viruses used to battle each other with a never-before-seen genetic coding system, unco...
09/17/2026

Before , there was VIPR — a tool viruses used to battle each other with a never-before-seen genetic coding system, uncovered by researchers in Jennifer Doudna's lab. Read more here: https://ow.ly/hZKO50ZOxwO

Pictured: Coauthors Terry Zhang, Peter Yoon, Kenneth Loi (left to right), making sure to include coauthor Trevor Docter (on the phone from Harvard)

09/16/2026

The latest in our Inside Genomics short video series — IGI researchers led by Sue Lynch at University of California, San Francisco and Ben Rubin University of California, Berkeley are creating a new way to prevent and treat childhood by editing microbes in the gut and lungs. Watch the full video here: https://ow.ly/tKEk50ZGLAw

🧬 Out today in Nature, IGI Investigator Yun Song has shared a new language model that can detect overlooked gene variant...
09/09/2026

🧬 Out today in Nature, IGI Investigator Yun Song has shared a new language model that can detect overlooked gene variants that impact human health. Learn more about how the Song lab is using to investigate the human genome: https://ow.ly/9B7a50ZLxsa

Out today in Nature Nanotechnology, a Q&A with IGI's Niren Murthy on his new way to engineer lipid nanparticles (LNPs) f...
09/08/2026

Out today in Nature Nanotechnology, a Q&A with IGI's Niren Murthy on his new way to engineer lipid nanparticles (LNPs) for safer genome editing. Learn more: https://ow.ly/oHvL50ZKZL1

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