CU Department of Biomedical Informatics

This Thursday, Bytes to Bedside welcomes Nitin Baliga, MSc, PhD, for a virtual discussion with DBMI! As the director at the Institute for Systems Biology (ISB), Baliga will share insights on how systems biology is revolutionizing personalized medicine and global health. Join us to explore these groundbreaking advancements!

Bytes to Bedside with Nitin Baliga, MSc, PhD The University of Colorado Anschutz Medical Campus is a premier medical facility changing the face of medicine through education, research, innovation, and patient care.

Artificial intelligence is making waves in medicine, but not in the way headlines might suggest. Instead of replacing doctors, AI is helping them focus more on patients by streamlining research, diagnostics, and care.

The University of Colorado Anschutz Medical Campus is at the forefront of this movement, and Casey Greene, PhD, a leading expert in computational biology and AI, shares insights on how this technology is building trust, reliability, and real-world impact in healthcare.

💬 How is AI reshaping medicine? What opportunities—and challenges—lie ahead?

Get answers straight from Greene in an exclusive Q&A on AI’s role in patient care & medical research. Read the full discussion at the link below.

AI in Healthcare: Results Over Hype What is AI in healthcare? How is my doctor using AI? An artificial intelligence expert explains how healthcare is uses AI for patients, medical research.

Understanding how our genes shape traits & diseases is a huge challenge. Traditional studies link DNA changes to gene activity but often miss how genes interact.

Enter PhenoPLIER—a powerful tool using machine learning to group genes based on co-expression & drug responses. This approach helps uncover hidden gene networks, making genetic studies more insightful & leading to personalized medicine breakthroughs!

Genetic studies through the lens of gene networks When citing this paper, please use the following: Subirana-Granés M, Hoffman J, Zhang H, Akirtava C, Nandi S, Fotso K, Pividori M. Genetic studies through the lens of gene networks. 2025. Annu. Rev. Biomed. Data Sci. 8. https://doi.org/10.1146/annurev-biodatasci-103123-095355

“Our ultimate goal is to discover the biological mechanisms relevant to women’s health and that underlie s*x differences across health and disease so we can translate this new knowledge into improved health for all.” — Barbara Stranger, PhD, professor of biomedical informatics, Lyda M. Ludeman Endowed Chair in Bioinformatics in Women’s Health Research.

✨ National Women’s Health Week (NWHW) is here! Every May, starting on Mother's Day, the U.S. Department of Health and Human Services (HHS), Office on Women's Health (OWH) leads this observance to empower women to prioritize their health. This year, from May 11-17, join us in highlighting key health issues, encouraging self-care, and championing well-being at every stage of life.

Barbara Stranger, PhD, Joins DBMI Faculty as Endowed Chair for Women’s Health Barbara Stranger, PhD, and her lab will dive deep into data to learn more about genetic variations between s*xes and how that translates into disease phenotypes.

Nurses spend more time with patients than most other healthcare professionals.” 🩺 AI-driven tools must enhance—rather than replace—their unique role. Join James Mitchell, PhD, MSc, and they discover how LLMs like ChatGPT could assist nurses in education, clinical decision-making, and workflow improvement.

Understanding Uses of Large Language Models in Nursing University of Colorado assistant professor of biomedical informatics James Mitchell, PhD, MSc, explains how software like ChatGPT is finding its way into nursing and why it’s important to study.

Happy National Nurses Week! 🎉 Nurses are the backbone of healthcare, and nursing informatics is empowering them with AI tools to enhance patient care and streamline decision-making. Discover how our team is shaping the future of healthcare ➡️ https://bit.ly/42Sir0O

Get ready to explore the world of health AI with the University of Colorado Anschutz Medical Campus! Casey Greene, PhD, shared his vision of technology’s future in the field and an overview of the unique challenges ahead.

“I think what gets me excited is not AI replacing your doctor. It's helping your doctor spend more time with you and less time in the chart,” shared Greene when he sat down to discuss where artificial intelligence in healthcare currently stands, future developments he sees on the horizon, as well as the opportunities – and potential pitfalls – these technologies have in store for both providers and patients.

AI in Healthcare: Results Over Hype What is AI in healthcare? How is my doctor using AI? An artificial intelligence expert explains how healthcare is uses AI for patients, medical research.

Approximately 8% of human DNA consists of repeating patterns called tandem repeats (TRs), which play a crucial role in genetic variation and disease. Yet, studying TRs remains challenging due to their complexity. Enter STRchive—a groundbreaking, publicly available tool designed to simplify TR research.

Developed by Harriet Dashnow, PhD, and a team from the University of Colorado School of Medicine, University of Utah, PacBio and the gnomAD team at the Broad Institute, STRchive integrates genomic data, clinical insights, and bioinformatics resources to empower researchers and clinicians in understanding the impact of TRs on human health.

💡 Why it matters: STRchive continuously evolves with new discoveries, ensuring accessibility and transparency for the scientific community.

Advancing Our Understanding of Repeating DNA Patterns Introducing STRchive from the University of Colorado. This tool recognizes the evolving landscape of tandem repeat diseases.

May is Mental Health Awareness Month, and AI is revolutionizing mental health care. CU psychiatrist and associate professor Joel Stoddard, MD, MAS, shares how new technology is shaping the future of treatment and support.

What’s the Future of AI in Mental Health Care? From AI-powered predictive analytics to the utilization of chatbots, CU psychiatrist and associate professor Joel Stoddard, MD, MAS, explains the important role new technology is playing in the mental health care field.

DBMI was excited to take part in the University of Colorado School of Medicine Administrative Showcase! Andrew Krahulik and Faisal Alquaddoomi led insightful presentations on enhancing workflows through automated effort reconciliation and the facilities and resources grant text generator. Their sessions aimed to empower administrative personnel with tools to streamline processes and improve department efficiency. It was a fantastic opportunity to share innovative solutions and collaborate with peers!

Exciting advancements in genetics! A recent study has revealed that some areas of our DNA mutate at unprecedented rates, offering new insights into human evolution and genetic diseases. This groundbreaking research, published in Nature, utilized advanced sequencing technologies to map genetic changes across generations. Such discoveries not only deepen our understanding of what makes us human but also pave the way for improved genetic counseling and disease prevention.

Human de novo mutation rates from a four-generation pedigree reference - Nature Analysis of more than 95% of each diploid human genome of a four-generation, twenty-eight-member family using five complementary short-read and long-read sequencing technologies provides a truth set to understand the most fundamental processes underlying human genetic variation.

📍 Where medicine, computational techniques and a clear vision come together to make life-changing progress.