The Narla Lab

"So proud of our research team for identifying a new therapeutic approach to treating TKI resistant leukemias. A special thanks to the Rogel Cancer Center for supporting the work." - Dr. Goutham Narla

JCI - PP2A modulation overcomes multidrug resistance in chronic lymphocytic leukemia via mPTP-dependent apoptosis 1Department of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, United States of America

The University of Michigan awarded 51 faculty members with professorships in 2022. As one of the honorees, Dr. Goutham Narla was appointed the Louis Newburgh Research Professorship in Internal Medicine and was recently honored along with the other faculty. A very big congratulations to Dr. Narla on this amazing recognition! To read more click on the link below.

https://mmheadlines.org/2023/03/u-m-medical-school-honors-51-faculty-members-appointed-to-professorships-in-2022/

This week is Graduate Student Appreciation Week and the Narla Lab would like to acknowledge and thank our graduate students for all their contributions to our work and lab. To learn about each of our grad students, visit our website and check out our about section! 〽️

https://www.thenarlalab.com/about

Dr. Caitlin O'Connor represented the Narla Lab and the University of Michigan at the AACR Annual Meeting 2022 in New Orleans, Louisiana. Dr. O'Connor received a AACR Scholar-in-Training Award, given to support early-career investigators who presented meritorious abstract in biomedicinal chemistry research at AACR 2022. Dr. O'Connor presented her work, Synthetic lethality by targeting ribonucleotide reductase in PP2A deficient uterine serous carcinoma. The entire Narla Lab is very proud!

Today we had our third collaborative mini retreat with the
DiFeo Lab. Great presentations from both groups! Looking forward to the next. 〽️

www.thenarlalab.com

The fourth of the Narla Lab's graduate students recently passed her preliminary exam and has officially achieved PhD candidacy. We are very proud and excited for Alexis Harold. To learn more about Alexis, check out our About page www.thenarlalab.com/about

About | The Narla Lab Founded by Dr. Goutham Narla, the Narla Lab is part of the Rogel Cancer Center at the University of Michigan in Ann Arbor.

Happy International Women's Day to every woman, but especially to the scientists in our lab that we work with every day! 🔬〽️ Get to know these brilliant women by visiting our website www.thenarlalab.com/about

The Narla Lab is very excited to share Dr. Caitlin O'Connor's first postdoctoral paper, published today in Cancer Research.

Targeting ribonucleotide reductase induces synthetic lethality in PP2A-deficient uterine serous carcinoma Uterine serous carcinoma (USC) is a highly aggressive endometrial cancer subtype with limited therapeutic options and a lack of targeted therapies. While mutations to PPP2R1A, which encodes the predominant protein phosphatase 2A (PP2A) scaffolding protein A-alpha, occur in 30-40% of USC cases, the c...

The Narla Lab is very excited to announce that we are expanding into our third lab space! Read more at www.thenarlalab.com/news

We've had some changes in the lab so we've updated our website - people, papers, and news. Go check it out!

The Narla Lab Our lab is interested in understanding the molecular processes that underlie the genesis and progression of human tumors.

While Rappta Therapeutics didn't make the final eight for the Spinoff Prize 2021, we're excited that Rappta Therapeutics is one of 10 "Ones to watch". https://www.nature.com/articles/d41586-021-01669-6

Learn more about Rappta Therapeutics here: https://www.rappta-therapeutics.com/ to see why it is one of ten university spin-off companies that the judges believe deserves close attention in the months and years ahead.

The Spinoff Prize: Ones to watch Here are ten university spin-offs that just missed making the final eight in the 2021 Spinoff Prize competition, but are worth keeping an eye on.