Remembering biochemist Kary Mullis, who discovered polymerase chain reaction (PCR).
Mullis was tired. He was out driving a distance he had driven so many times that he could drive it in his sleep. It was dark and his thoughts wandered. After a while, all the pieces of the puzzle fell into place. He finally had to stop his car to think properly.
Mullis was awarded the chemistry prize for his invention of the process known as polymerase chain reaction (PCR), in which a small amount of DNA can be copied in large quantities over a short period of time. By applying heat, the DNA molecule's two strands are separated and the DNA building blocks that have been added are bonded to each strand. With the help of the enzyme DNA polymerase, new DNA chains are formed and the process can then be repeated. PCR has been of major importance in both medical research and forensic science.
Read more about how Mullis discovered PCR: https://bit.ly/2F53qwS
Magwa Primary School
Magwa primary school is located in Jinja city in Uganda.
Operating as usual
Remembering biochemist Kary Mullis, who discovered polymerase chain reaction (PCR).
Now on display: A signed portrait photograph given to President and Mrs. Kennedy by Queen Elizabeth II after their state visit to the United Kingdom in 1961.
On this week's blog, learn about how John Singer Sargent's travels to Spain may have influenced Isabella and her husband's interest in and travel to the region. Read over at the link https://bit.ly/3zNrocK
Image: The Spanish Cloister, John Singer Sargent (American, 1856-1925), El Jaleo, 1882. Isabella Stewart Gardner Museum, Boston.
Mary Jackson was NASA's first black female engineer – her story was told in the "Hidden Figures" book and film. After 34 years at NASA, Jackson had earned the most senior engineering title available, then went on to influence the hiring and promotion of women in NASA's science, engineering, and mathematics careers.
"Tiningo’ si Sirena" (2021), which recently joined the MFA's collection, is a nearly life-size painting by artist Gisela Charfauros McDaniel of her mother, scholar Antoinette CHarfauros McDaniel. The title means “knowledge of Sirena” in CHamoru, the Indigenous language of Guåhan (Guam) and the Commonwealth of the Northern Mariana Islands. “Sirena” (Spanish for mermaid) is an important CHamoru legend 🧜♀️
This month on our blog, Ellyn McColgan Assistant Curator of Native American Art Marina Tyquiengco—the MFA’s first CHamoru curator—sits down with the artist and her mother to discuss the process of making this multimedia artwork that honors matrilineal histories. Read their conversation and listen to the sound piece: https://bit.ly/3BzttKF
🎨: "Tiningo’ si Sirena" (2021), oil on canvas, clothing, objects from subject-collaborator, shells, pearls, sound
Astrophysicist Subrahmanyan Chandrasekhar, known as ‘Chandra’, photographed on 19 October 1983, the day he was awarded the Nobel Prize in Physics for his work on the evolution of stars.
Chandrasekhar adopted a highly unusual approach to his research, investigating a fresh field of study each decade, such as how stars die, how radiation passes through a star’s atmosphere and the theory of black holes. Each decade he followed a similar routine; writing a series of papers that solved the unsolved problems in that field, before finally publishing a book that summarised his results and presented the whole field in a new and clearer light. However, it is mainly for an early triumph, a theory developed while on a long sea voyage from India to the UK and that began his voyage through the stars, that Chandrasekhar was awarded the 1983 Nobel Prize in Physics.
Learn more: https://bit.ly/2KdbjEL
"This in effect is, the faith of all physicists; the deeper we seek, the more is our wonder excited, the more is the dazzlement for our gaze."
As a 14-year-old boy, science genius Abdus Salam gained the highest marks ever recorded for the Matriculation Examination at the University of the Punjab in the beginning of the 1940s. When he cycled home from Lahore the whole town welcomed him.
In 1949, Salam was awarded a scholarship to study a double bachelor's degree in mathematics and physics at University of Cambridge. In 1950 he received the Smith’s Prize from University of Cambridge for the most outstanding pre-doctoral contribution to physics.
During his career in science, Salam presented many scientific breakthroughs and innovative theories such as the Pati–Salam model, Grand Unified Theory and research on supersymmetry.
In 1979, he shared the Nobel Prize in Physics with Sheldon Glashow and Steven Weinberg. They made significant contributions to the electroweak unification theory.
Read more about Abdus Salam: https://bit.ly/3dbeQx6
On this day in 1912 Nobel Prize laureate Niels Bohr married Margrethe Nørlund. Their partnership would extend into Bohr's work as he often wrote papers through a process of dictation, which Margrethe would type up for him.
One of their sons, Aage Bohr, would go onto receive a Nobel Prize in Physics, just like his father. Niels received the 1922 physics prize for his model of the structure of the atom and Aage Bohr was awarded the 1975 physics prize for work on the structure of the atomic nucleus.
Today we lost a trailblazer, pioneer and a true space advocate who navigated tough challenges with great determination and grace. Thank you for your help to carve a path for a diverse future in the world and at NASA.
Fair winds and following seas, Lt. Uhura.
Photo credit: NASA/Bill Ingalls
The Soma Cube, Again The Soma Cube brings back memories.ContentsPiet HeinBill McKeemanThe original soma demoA new Soma demoSoftwareUpdatePiet HeinPiet Hein (1905-1996) was an extraordinary Danish inventor, mathematician, poet and philosopher. He invented the Soma Cube puzzle in 1933. I wrote a blog post about Hein and s...
Cleve’s Corner: Cleve Moler on Mathematics and Computing - MATLAB & Simulink Cleve Moler shares his thoughts on numerical computing and MATLAB — Cleve’s Corner: Cleve Moler on Mathematics and Computing in MATLAB Central Blogs.
Remembering Nobel Prize laureate Ahmed Zewail.
In the late 1980s Zewail developed methods for studying chemical reactions in detail. Chemical reactions in which molecules held together by atoms meet and reorganise into new compounds are one of nature's most fundamental processes.
However this transition happens too quickly for us to easily see - in a matter of femtoseconds. One femtosecond is 0.000000000000001 seconds, which is to a second as a second is to 32 million years.
By using laser technology to produce flashes of light just a few femtoseconds long, Zewail was able to visualise these reactions in slow motion - and to see what actually happens when chemical bonds break and new ones are created.
Zewail's experiments led to the birth of the research area called femtochemistry, which enables us to understand why certain chemical reactions take place but not others.
Image: Ahmed Zewail at the Nobel Prize award ceremony in Stockholm on 10 December 1999.
Read his biography: https://bit.ly/3IZlEQc
How I harnessed the wind At age 14, in poverty and famine, a Malawian boy built a windmill to power his family's home. Now at 22, William Kamkwamba, who speaks at TED, here, for the second time, shares in his own words the moving tale of invention that changed his life.
On stage was Senator Kamara Harris, with her beautifully chiseled features, sharp as a razor, and VP Pence not so bad looking either with his spherical head and ever so softly-spoken as a high priest in a monastery. At times he spoke so softly we could barely hear what he had to say.
Their task for the evening was to convince the American people and the rest of the World that their candidate had the "right stuff", the skills, heart, and fortitude to lead the American people out of a debilitating pandemic that has frozen the entire nation and wreaked havoc on the world economy.
It was time for each Vice President pick to tell us about the depth of the soul of the man they'd agreed to accompany as their running mate. In essence, President Trump and former Vice President Biden were being virtually weighed on that stage, to see who qualifies to win the title of "Mr. President" for the next four years.
Senator Harris wasted no time. impassioned by Joe Biden's record of compassion and demonstrable success of having led the American people out of a tough economic crisis, she punched with the gloves of a heavyweight boxer, attacking President Trump's record on -response to the pandemic, she appealed to the American people on race relations and questioned the prudence of forcing a supreme court nominee through the Senate on the eve of an election.
VP. Pence was also hot on her trail, he was a boxer with a lot of debating body jabs, and he unleashed them all last night. He attacked her record on incarceration rates of black folks, he accused the Democrats of being idle while manufacturing jobs were fleeing to China. He said they would take away fracking jobs, and raise the tax of every American $2000 dollar.
Even though each candidate carried on beyond their allotted time, they were both civil about bringing themselves back to the moderator's rules and they were very careful not to interrupt each other having learned from the Presidential debate unruly debacle.
In a period of high unemployment and economic and health uncertainty, there were not too many takeaways to reassure the American people that things would be done differently. Senator Harris talked of the need to save the Affordable Care Act, she did not talk about any economic stimulus to address the joblessness or new ideas to get rid of the pandemic.
The debating points were as old and jaded as the folks on stage. No, one talked about the quest to embrace quantum computing or genetic editing as a promise for future jobs and as a response to pandemics. It seemed like these ideas had gone with the cleverness of the Bill Clinton era when his platform steered and piqued the interest of the American people to the high tech innovative idea of the Internet of things.
We were treated to the same economic bugle call that has not materialized for the last 30 years -of building the infrastructure, peppered with fracking, and the idea of green jobs that never fully materialized during the Obama era. We were also treated to President Trump's economic measures of a silly tariff war with China, which has yielded no positive results economically, not to farmers or manufacturers.
The thought in the American mindset is that money from such economic tariffs would have gone directly to communities in the United States hard hit by Chinese manufacturers, textile towns such as Fall River Massachusetts, poultry, and beef, steel towns bleeding economically all over the nation, being forced to close down.
On the social unrest front and response to the pandemic, no innovative approaches were fully articulated by either Party last night, nor was there any mention of solving the immigration problem -of millions of immigrants waiting in the shadows to be regularized by either Party that wins the election.
On our lips, we remained with the unspoken words of one of their own from a different era Vice President Walter Mondale -"Where is the beef"?
Ugandan in Boston.
A couple of weeks have passed since the grounding of students -now sitting at home and getting giddy about the idleness of it all- a reprieve welcome by many, especially those who were tired of the routine of waking up so early and jumping into the rigid regimens of schools, daily attendance of long classes loaded with content heuristics that stretch the limits and boundaries of unfilled mind slates.
Locked down parents are juggling with far too many things- that have rushed at them with untold simultaneity. Some are out of jobs and others are working from home - all eyes and worries placed on the course and onslaught of the Coronavirus. Will it be my auntie Wilma who drinks a bit or uncle Ben who is diabetic both in the most vulnerable age group and in their retirement years. What if it starts right here at home, how prepared are we as a family, have we put our Wills, medical proxies, burial plots in order, should we have a discussion about death and dying, are we ready to be put in massive graves -if the worst comes, or would we rather be cremated en-mass.
Locked down parents are also mighty glad that schools often the source of Flu in the family every season are padlocked, closed for the first time due to the Flu season. Because no matter how many Flu shots everybody gets- it seems like college students always return home with strep throat or mono and the younger students religiously carry back the sniffles.
This time the sniffles and coughs are laced with a SAR-COV-2(COVID-19) virus a two-headed tiny microbe -with genetic markers from the Bat and the Pangolin (Olugave) -a known reservoir for the virus' S-gene that easily code its way into our own DNA to unleash deadlier effects of the common flu as we have never known. COVID-19 wreaks havoc by constricting small veins and capillaries to inflame the inside of one's lungs -blocking off the exchange of oxygen, this is how it brews deadly pneumonia and fills up your already inflamed lungs with fluid to leave you gasping for that last breath to expire.
It is a deadly contagion, that has paralyzed the entire world and brought stocks and humans alike to a reduced state and brought a new height of impotence.
Parents are mighty glad that the forceful hand of the Government has decisively put measures in place save lives, such as the grounding of the students, the closing of restaurants and the request for employers to categorize their staff into essential and non-essential staff, this has lessened their worries of contracting this air and surface sticking virus from the workplace. We further urge Government leadership to provide tax incentives to internet service providers and have an emergency policy requiring them to give students now idle at home free data quotas to give them the ability to work remotely and take advantage of other educational freebies such as the many IVY league college menus of OpenCourseware classes(MIT), Amazons free books, and other known sources as Khanacademy that are available on the internet!
Toni Morrison, Nobel laureate who transfigured American literature, dies at 88 In books such as “The Bluest Eye” and “Beloved,” Ms. Morrison gave voice to the African American experience.
Chimamanda Ngozi Adichie becomes first African to deliver Yale graduation speech Chimamanda Ngozi Adichie, the renowned novelist behind hit written works such as “Americanah” and “We Should All Be Feminists,” made history at Yale University’s graduation festivities over the weekend.
The era of s***king is finally over The American Academy of Pediatrics recommends that parents not s***k, hit or slap their children. Elizabeth Gershoff says that's a good thing -- s***king doesn't work, affirms solving problems with physical force, and the common response that "I was s***ked as child but I turned out OK" may not actu...
COULD THIS BE THE LONG AWAITED CURE FOR SICKLE CELL ANEMIA!
More on the trial aiming to cure sickle cell 60 Minutes reported on a gene therapy trial that may be a cure for patients living with the bone-crushing pain of sickle cell disease. Here's how to join
The College Graduate and Public Life "It is proper to demand more from the man with exceptional advantages than from the man without them."
The Nobel Prize in Physiology or Medicine 2018 The Nobel Prize in Physiology or Medicine 2018 was awarded jointly to James P. Allison and Tasuku Honjo "for their discovery of cancer therapy by inhibition of negative immune regulation".
Opinion | Hell hath no fury like an entitled white man denied I'm not here for the entitlement of Kavanaugh and Graham.
A very sad day for Physics, when one of its leading poets dies. https://www.facebook.com/photo.php?fbid=10155608507517462&set=pcb.10155608507687462&type=3&theater
The Real Message of the 2017 Nobel Prize in Physiology or Medicine The year’s first Nobel went to three Americans who pioneered the study of the biological clock. What does it mean?
Lisa Randall — Dark Matter, Dinosaurs, and Extra Dimensions The astounding interconnectedness of everything and the human questions at its center.
Prom 62: Chineke! - Prom 62 Hailed by critics as ‘fresh’ and ‘brilliant’, the UK’s first majority BME orchestra Chineke! makes its Proms debut in a programme including works by Pulitzer Prize-winning George Walker and young British composer Hannah Kendall, whose The Spark Catchers takes inspiration from the urgent energy of Le...
Angela Merkel and her press corps show how big democracies are supposed to operate The contrast between the chancellor and Donald Trump could not be greater
What’s really happening during an LHC collision? It’s less of a collision and more of a symphony.
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MAGWA PRIMARY SCHOOL Magwa Crescent Avenue P. O. Box 1113
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We are the only hair and beauty school in Uganda offering world class hair and beauty education that
Old Kakira Road Bugembe
Helping Orphans and the unprivileged child attain Education in the struggling community of Jinja Uga
SWOH school in Uganda founded by widows and widowers that had orphans who were stigmatized due to th