BnML - Behavioral & Molecular Lab

In 2018, Ana Marote, a former PhD student from BnML - Behavioral & Molecular Lab and ICVS, in collaboration with Dr Laurent Roybon’s lab at Lund University, published 3 reports in Stem Cell Research on the generation of iPSCs lines from Parkinson’s disease patients.

Find out more about these works:
https://lnkd.in/g-Qk-HT
https://lnkd.in/gWt5kTZ
https://lnkd.in/gvhANgP

For more information about these and other projects please contact us at [email protected].

Generation of an induced pluripotent stem cell line (CSC-46) from a patient with Parkinson's disease carrying a novel p.R301C mutation in the GBA gene Mutations in the glucocerebrosidase (GBA) gene have been associated with the development of Parkinson's disease (PD). An induced pluripotent stem cell…

Afinal, pode ou não o cérebro humano gerar novos neurónios durante a vida adulta? Um dos elementos da equipa BnML debate este tema num artigo de opinião, no jornal Público desta sexta-feira!

Opinião. Novos neurónios no cérebro humano adulto Afinal, tem o sistema nervoso do ser humano capacidade ou não de gerar novos neurónios ao longo da vida adulta?

B'nML wishes you a very Merry Christmas and a Happy New Year!

In our brain, new neurons are born everyday with the ability to participate in different dimensions of our behavior. Researchers from BnML - Behavioral & Molecular Lab have identified the presence of the protein AP2gamma within the hippocampus and described its role in regulating the generation of new neurons. Results of the study show how these neurons are relevant for inter-regional communication between brain regions and for cognitive functions, such as learning and memory. The study is now out in the journal Molecular Psychiatry, from Nature Publishing Group: http://www.nature.com/mp/journal/vaop/ncurrent/full/mp2016169a.html

Interested in how the immune system participates in the pathogenesis of anxiety disorders? Researchers from BnML - Behavioral & Molecular Lab have collaborated with researchers from University of Coimbra to explore the cross-talk between pre-natal glucocorticoid exposure, remodeling of microglial cells and development of anxiety traits. The study is now out in the prestigious journal Molecular Psychiatry, from Nature Publishing Group. To read more follow the link! http://www.nature.com/mp/journal/vaop/ncurrent/abs/mp2016173a.html

Molecular Psychiatry - Adenosine A2A receptor regulation of microglia morphological remodeling-gender bias in physiology and in a model of chronic anxiety Molecular Psychiatry publishes work aimed at elucidating biological mechanisms underlying psychiatric disorders and their treatment

The School of Medicine of the University of Minho, and its research institute, the ICVS, celebrate their 16th anniversary! BnML - Behavioral & Molecular Lab congratulates these institutions and is proud to be part of this wonderful project as a partner in innovation and state of the art research!

Scientists have discovered why the 'happy hormone' makes people more anxious

Escola de Ciências da Saúde abre portas a intercâmbios nos EUA (C/vídeo) É este o principal objectivo do protocolo assinado esta 3ª feira entre a Universidade do Minho e a Fundação Luso-Americana para o Desenvolvimento.

Bn'ML participated in an internship program promoted by "A minha Escola de Ciências". Thank you Cristiana and Carolina for your active participation!
More info: http://amec2016ecuminho.pt/amec-nas-empresas/

A Bn'ML - Behavioral and Molecular Lab é uma Start-up da Universidade do Minho, em estreita associação com o Instituto de Investigação em Ciências da Vida e da Saúde (ICVS).

Receberá nos dias 21, 22 e 23 duas alunas, do Colégio João Paulo II e do Colégio Luso Internacional de Braga, dando-lhes a oportunidade de experimentar a investigação pré-clínica em modelos animais de doença.

Postgraduate course “Epigenetics - from mechanisms to disease” One major challenge in biology is to understand how epigenetic modifications contribute to transcriptional plasticity. This issue is of particular importance in the brain, where experience-dependent changes in gene transcription are essential for its normal activity. Indeed, loss-of-function of key…

https://bbrfoundation.org/brain-matters-discoveries/a-milestone-in-the-search-for-schizophrenia%E2%80%99s-causes

A Milestone in the Search for Schizophrenia’s Causes Exciting news reported today in Nature and featured in the New York Times points to one of the likely causes (among others) of s

https://www.hospitaldebraga.pt/NoticiaDetalhe/O+Hospital%5CNoticias/Jornadas+CCa

Hospital recebeu Jornadas de Investigação Clínica & Investigação do Centro Clínico Académico -... O Hospital de Braga foi o anfitrião das primeiras Jornadas organizadas pelo Centro Clínico Académico de Braga (CCA) sob o tema da Investigação Clínica & Inovação.