FCPS Part1 Q BANK

FCPS Part1 Q BANK

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THIS PAGE IS ABOUT DISCUSSING DIFFERENT KIND OF PROBLEMS & MCQs RELATED TO FCPS PART 1.WE MAKE SURE Copyright © 2009.

WE MAKE SURE THAT NO MCQ GET REPEATED SO ALL THE DATA UPLOADED WILL BE FRESH AND NEW ! INVITE MORE AND MORE FRIENDS OF YOURS TO THIS GROUP & UPLOAD MORE AND MORE MCQS , DISCUSS DIFFERENT PROBLEMS , ALSO SHARE THE BOOKS THAT U R STUDYING FOR UR PART 1. IF YOU HAVE ALREADY CLEARED IT PLZ SHARE & GUIDE YOUR EXPERIENCE TO FRESH CANDIDATES.

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پریس ریلیز

ینگ ڈاکٹرز ایسوسی ایشن پنجاب کے وفد کی گورنر پنجاب سے ملاقات

لاہور (پریس ریلیز) – ینگ ڈاکٹرز ایسوسی ایشن (YDA) پنجاب کے وفد نے گورنر ہاؤس لاہور میں گورنر پنجاب سردار سلیم حیدر سے ملاقات کی۔ ملاقات میں ینگ ڈاکٹرز ایسوسی ایشن سروسز ہسپتال کی سینئر قیادت نے شرکت کی، جن میں چیئرمین YDA پنجاب ڈاکٹر مدثر نواز اشرفی، وائس چیئرمین YDA سروسز ہسپتال ڈاکٹر عمران بھٹی، جوائنٹ سیکرٹری YDA پنجاب ڈاکٹر ذیشان نور ملک، اور صدر جسٹس فار ایف ایم جیز ڈاکٹر رفاقت گجر شامل تھے۔

اس ملاقات میں صوبے بھر کے ہسپتالوں میں درپیش مسائل، طبی سہولیات کی بہتری اور ڈاکٹروں و مریضوں کے حقوق پر تفصیلی تبادلہ خیال کیا گیا۔ وفد نے گورنر پنجاب کو ہسپتالوں میں مریضوں کے لیے مزید سہولیات کی فراہمی اور طبی عملے کی کمی کو پورا کرنے کے لیے فوری اقدامات اٹھانے پر زور دیا۔

مزید برآں، YDA پنجاب کے وفد نے گورنر پنجاب، جو کہ تمام میڈیکل یونیورسٹیوں کے پیٹرن اِن چیف بھی ہیں، سے درخواست کی کہ وہ صوبے کے تمام ہسپتالوں کا سرکاری دورہ کریں تاکہ طبی شعبے کے مسائل کا براہ راست مشاہدہ کر سکیں۔

وفد نے گورنر پنجاب کو ینگ ڈاکٹرز ایسوسی ایشن پنجاب کے زیرِ اہتمام منعقد ہونے والے کنونشن میں بطور مہمان خصوصی شرکت کی دعوت بھی دی، جسے انہوں نے خوش دلی سے قبول کیا۔

ینگ ڈاکٹرز ایسوسی ایشن پنجاب اپنے مشن پر کاربند ہے اور ڈاکٹروں و مریضوں کے حقوق کے تحفظ کے لیے ہر فورم پر اپنی آواز بلند کرتی رہے گی۔

جاری کردہ:
ینگ ڈاکٹرز ایسوسی ایشن پنجاب

13/05/2021

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12/05/2020

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29/07/2018

MD/MS-2016

80.Question
Melanocytes are derived from:

Options:
Neuroectoderm

Options:
Mesoderm

Options:
Ectoderm

Options:
Neural crest cells
Correct:
Derivatives of Neural crest Cells: * Connective tissue and bones of face and skull * C-cells of thyroid * Conotruncal septum in heart * Odontoblasts * Autonomic ganglia * Ganglia along spinal and cranial nerves * Adrenal medulla * Schwann cells and Glial cells * Melanocytes

Options:
Subcutaneous tat

M
MD/MS-2016

81.Question
In Kluvar bucy syndrome the lesion is localized in:

Options:
Basal ganglia

Options:
Pineal gland

Options:
Hypothalamus

Options:
Amygdala
Correct:
Features of Kluvar Bucy syndrome: Unilateral or bilateral destruction of Amygdaloid nucleus in these patients results in emotional instability,behavioural changes, restlessness, hyperphagia, visual agnosis and hypers*xuality.

Options:
Thalamus

M
MD/MS-2016

82.Question
All of the following are true statements regarding clara cells EXCEPT:

Options:
They have potential to divide & differentiate into ciliated cells

Options:
They secrete glycosaminoglycan

Options:
They are found in secondary bronchi
Correct:
Clara cells are only found in bronchioles like primary, terminal and respiratory.

Options:
They metabolize air-borne toxins

Options:
All of these

M
MD/MS-2016

83.Question
In adults,T-lymphocytes are produced in:

Options:
Thymus

Options:
Bone marrow
Correct:
T-lymphocytes are produced in bone marrow and matured in Thymus.

Options:
Spleen

Options:
Liver

Options:
Lymph nodes

M
MD/MS-2016

84.Question
All of the following regarding popliteus muscles are true EXCEPT:

Options:
Attached to the lateral aspect of lateral femoral condyle

Options:
When the knee is fully extended, the muscle works to rotate the femur laterally on the tibia

Options:
It also rotates the tibia medially on femur,when foot is off the ground.

Options:
Muscle of superficial group of posterior compartment
Correct:
Muscles of the superficial compartment of the leg are GPS: Gastrocnemius,Plantaris and Soleus Muscles of the deep compartment are: Popliteus, FHL,FDL and Tibialis posterior

Options:
None of these

M
MD/MS-2016

85.Question
All of the following regarding klinefelter syndrome is true EXCEPT:

Options:
It is characterized by testicular hypertrophy and atrophy of breast
Correct:
Klinefelter Syndrome: * Trisomy of s*x chromosome * Mostly due to nondisjunction * Possible Karyotypes are 47XXY, 48 # # * Clinically Tall male with testicular atrophy and Gynaecomastia * Positive barr body

Options:
The karyotype in 80% patient is 47 XXY

Options:
Non disjunction of XX homologus is most common causative agent

Options:
Occasionally patients have karyotype of 48 # #

Options:
Tall male

M
MD/MS-2016

86.Question
Which of the following prostaglandins mediate pain?

Options:
PGE2
Correct:
prostaglandins PGE2 mediates pain.

Options:
PGI2

Options:
PGD2

Options:
PGF2

Options:
PGA2

M
MD/MS-2016

87.Question
All of the following regarding GABA are correct EXCEPT:

Options:
It is inhibitory neurotransmitter only in brain

Options:
GABA-A receptor activation opens Na channels
Correct:
GABA: it is an inhibitory neurotransmitter in brain only i.e. CNS. GABA-A receptor activation opens the chloride channels and chloride influx causes hyperpolarization.

Options:
GABA-B receptor activation opens either K-channels or close Ca+2 - channels

Options:
GABA-A receptors are activated by benzodiazepines

Options:
None of these

M
MD/MS-2016

88.Question
Regarding primary biliary cirrhosis all of the following are ture EXCEPT:

Options:
Autoimmune disorder

Options:
Granulomatous destruction of bile ducts in portal triad

Options:
More common in men
Correct:
Primary Biliary cirrhosis common in females.

Options:
Antimitochondrial Ab are present in >90% cases

Options:
Present in middle age

M
MD/MS-2016

89.Question
Hyperaldosteronism occurs due to:

Options:
Adenoma of zona glomerulosa
Correct:
Aldosterone is a mineralocorticoid and released by zona Glomerulosa so primary hyper-aldosteronism is caused by hyperplasia or adenoma of zona Glomerulosa.

Options:
Hypokalemia

Options:
Fluid overload

Options:
Increase renal blood flow

Options:
All of these

M
MD/MS-2016

90.Question
Lung cancer can be caused by:

Options:
Asbestosis
Correct:
Asbestos and smoking are the most important Carcinogens of Lung cancer.

Options:
Pneumoconiosis

Options:
Anthracosis

Options:
Silicosis

Options:
Radon

M
MD/MS-2016

91.Question
Raised levels of Alkaline phosphatase are seen in:

Options:
Obstructive jaundice

Options:
Paget"s disease of bone

Options:
Osteomalacia

Options:
Bone mets
Correct:
Alkaline Phosphatase is increased in both bone and liver diseases.

Options:
All of these

M
MD/MS-2016

92.Question
SGPT is an enzyme specific for disease in:

Options:
Liver
Correct:
SGPT is marker of liver cell necrosis, more specific for liver than any other tissue.

Options:
Heart

Options:
Skeletal muscle

Options:
Lung

Options:
Bone

M
MD/MS-2016

93.Question
Maximum Co2 is transported in the form of:

Options:
HCo3 ion
Correct:
CO2 reacts with H2O in a reaction to form bicarbonate ions ( HCo3 )and so more than 70% is carried in blood in form of these ions.

Options:
Carbamino compound

Options:
Dissolved in plasma

Options:
Undisclosed in plasma as Co2

Options:
None of these

M
MD/MS-2016

94.Question
ABGS of patient show PH 7.2, PCO2 66, HCo3 mmol/L, what is the most likely diagnosis?

Options:
Compensated metabolic acidosis

Options:
Compensated resp. acidosis
Correct:
Primarily its resp. acidosis and its compensated because of increased levels of HCO3.

Options:
Un compensated metabolic acidosis

Options:
Un compensated resp. acidosis

Options:
None of these

M
MD/MS-2016

95.Question
The surface epithelium of palatine tonsil is:

Options:
Stratified squamous
Correct:
Covering epithelium of palatine tonsil is same as that of the oral cavity i.e. stratified squamous epithelium.

Options:
Stratified columnar

Options:
Simple columnar

Options:
Undifferentiated

Options:
Adenosquamous

M
MD/MS-2016

96.Question
In a newborn, which of the following immunoglobulins (Ig) are found in maximum quantity?

Options:
IgM

Options:
lgA

Options:
lgE

Options:
lgG
Correct:
In a newborn, IgG has the highest levels as it is the only lg which can cross placenta.

Options:
All of above

M
MD/MS-2016

97.Question
Which of the following arteries is blocked in stroke involving both motor and sensory areas?

Options:
Anterior cerebral art

Options:
Middle cerebral art
Correct:
Sensory and motor areas located on the lateral surface of cerebrum are supplied by MCA( Middle Cerebral Artery)

Options:
Post cerebral art

Options:
Vertebral art

Options:
Posterior cerebral art

M
MD/MS-2016

98.Question
The intestinal colonic polyp that is not related to malignancy is:

Options:
Tubular polyp

Options:
Villous polyp

Options:
Tubulovillous

Options:
Hyperplastic
Correct:
Hyperplastic or metaplastic Colonic Polyps are NOT pre-malignant.

Options:
Familial adenomatous polyposis

M
MD/MS-2016

99.Question
Anticonvulsant of choice during eclampsia is:

Options:
Phenytoin

Options:
Carbamazepine

Options:
Mg So4
Correct:
Mg So4 is the drug of choice in eclamptic seizures.

Options:
Phenobarbitone

Options:
Lamotrigine

M
MD/MS-2016

00.Question
Tensor veli palatine is supplied by:

Options:
Mandibular division of CN V
Correct:
All muscles of soft palate are supplied by Pharyngeal plexus except Tensor veli palatini which is supplied by mandibular division of V CN.

Options:
CN IX

Options:
CN X

Options:
Maxillary division of CN V

Options:
CN VII

M
MD/MS-2016

01.Question
Which of the following is not a feature of chronic renal failure?

Options:
Anemia

Options:
Hypcalcemia

Options:
M. acidosis

Options:
Hypophosphatemia
Correct:
CRF is characterized by: * Anemia (normocytic normochromic) due to decrease production of EPO * Hypocalcemia due to lack of active Vit.D * M. acidosis due to failure of H-ions excretion * Hyper Kalemia

Options:
Hyperkalemia

M
MD/MS-2016

02.Question
Nasolacrimal duct opens in:

Options:
Superior meatus

Options:
Middle meatus

Options:
Inferior meatus
Correct:
Structures opening in meatuses of lateral wall of nose: * Superior; Post.ethmoidal sinus* Middle; frontal, ant. and middle ethmoidal sinuses * Inferior; Nasolacrimal duct

Options:
Superior conca

Options:
None

M
MD/MS-2016

03.Question
Axillary artery starts at:

Options:
Inner border of first rib

Options:
Outer border of first rib
Correct:
Axillary artery begins at outer border (lateral) of first rib and ends at the inferior border of Teres major.

Options:
Lower border of pectoralis minor

Options:
Lower border of pectorals major

Options:
Sternocleido mastoid muscle

M
MD/MS-2016

04.Question
Which of following substances is not found in the cytoplasm of NK cells?

Options:
TNF - Alpha
Correct:
TNF - Alpha is not present.

Options:
Lymphotoxin

Options:
Lysozyme

Options:
TNF - B

Options:
Perforin

M
MD/MS-2016

05.Question
Substances that are immunogenic only when coupled to a protein carrier are called:

Options:
Opsonins

Options:
Haptens
Correct:
Hapten: Its antigen but not immunogen and can be converted into immunogen when combined with a carrier protein.

Options:
Adjuvants

Options:
Toxoids

Options:
Epitopes

M
MD/MS-2016

06.Question
The sites in or on antigens with which antibodies react are called:

Options:
Haplotypes

Options:
Isotypes

Options:
Epitopes
Correct:
Epitope: It’s a site on antigen which reacts with antibody and the corresponding site on antibody is called Paratope. Haplotype is term used to mention two sets of genes. Different types of lgs are called Isotypes. Idiotype is a unique three dimensional shape of pocket for antigens on antibodies.

Options:
Idiotypes

Options:
Monotypes

M
MD/MS-2016

07.Question
Regarding immunoglobulin all of the following are true EXCEPT:

Options:
IgG is the major immunoglobulin in the serum

Options:
IgE is associated with immediate type of hypersensitivity reaction (Asthma, Anaphylayis)

Options:
Secretory IgA is predominant immunoglobulin in various secretions (Saliva, Tears, Colostrum)

Options:
IgM is predominant antibody in early primary immune response and predominant Ab produced by fetus

Options:
IgG cannot cross placenta
Correct:
IgG is the most abundant Ig in the blood and it can cross placenta as well.

M
MD/MS-2016

08.Question
All of the following complement components are in alternative pathway EXCEPT:

Options:
C1, C2, C4
Correct:
Complement System components are: * Classical pathwary: C1,2 and 4 * Alternative: Properdin, Factors B,D and Magnesium * Common pathwary: C3,5,6,7,8,9

Options:
C5, C6, C7

Options:
C3B

Options:
C8, C9

Options:
Properdins

M
MD/MS-2016

09.Question
The epithelium of Nasopharynx is:

Options:
Pseudostratified ciliated columner
Correct:
Same as that of respiratory epithelium i.e. Pseudo stratified columner ciliated.

Options:
Stratified squamous keratinized

Options:
Stratified squamous non-keratinized

Options:
Simple cuboidal

Options:
Adenosquamous

M
MD/MS-2016

10.Question
Thiazide diuretics cause all side effects EXCEPT:

Options:
Hyonatremia

Options:
Hyper kalemic
Correct:
Side effects of Thiazide diuretics; - Hyper Glycemia - Hyper uricemia - Hyper lipidemia - Hypo natremia - Hypo kalemia

Options:
Hyper glycemia

Options:
Hyper lipidemia

Options:
Hyper uricemia

M
MD/MS-2016

11.Question
All of the following regarding functions of thyroid hormones are correct except:

Options:
Increased BMR

Options:
Increased glycogenolysis

Options:
Decreased lipolysis
Correct:
Normal or increased level of thyroid hormones promote lipolysis while decrease levels promote lipogenesis.

Options:
Increased gluconeogenesis

Options:
None of these

M
MD/MS-2016

12.Question
Calcitonin is tumor marker of:

Options:
Follicular ca of thyroid

Options:
Papillary ca of thyroid

Options:
Anaplastic ca of thyroid

Options:
Medullary ca of thyroid
Correct:
Thyroglobulin is tumor marker of Follicular and Papillary cancer of thyroid, while Calcitonin is for Medullary and Anaplastic does not have any marker.

Options:
Germ cell tumor

M
MD/MS-2016

13.Question
Neisseria meningitides releases:

Options:
Exotoxin

Options:
Endotoxin
Correct:
Being G-ve coccus it produces Endotoxin.

Options:
Both

Options:
None

Options:
Enterotoxin

M
MD/MS-2016

14.Question
Regarding diphyllobothrium latam all of the following are true EXCEPT:

Options:
It is transmitted through undercooked fish which has ingested larvae

Options:
The intermediate host is fish

Options:
Main site affected in human body is intestine

Options:
The drug of choice is praziquantal

Options:
It belongs to Trematoda
Correct:
Diphyllobotherium Latum called fish tape worm belongs to Cestode not trematoda.

M
MD/MS-2016

15.Question
Regarding vibrio cholera all of the following are true EXCEPT:

Options:
It is comma shaped

Options:
It causes rice watery diarrhea

Options:
Enterotoxin permanently activates Gs protein

Options:
Diarrhea is associated with fever and stool shows large number of leucocytes
Correct:
Vibrio cholera: After a to 48 hour incubation period, symptoms begin with the sudden onset of painless watery diarrhea that may quickly become voluminous and is often followed by vomiting. The patient may experience accompanying abdominal cramps, probably from distention of loops of small bowel as a result of the large volume of intestinal secretions. Fever is typically absent.

Options:
It is oxidase positive

M
MD/MS-2016

16.Question
Epitheloid cells are:

Options:
Activated macrophages
Correct:
These are active macrophages.

Options:
Activated lymphocytes

Options:
Activated plasmas cells

Options:
Activated eosinophils

Options:
Activated RBCs

M
MD/MS-2016

17.Question
Caseous gnanulomas are found in all of the following conditions EXCEPT:

Options:
Tuberculosis

Options:
Histoplasmosis

Options:
Syphilis

Options:
Brucellosis
Correct:
Remember the rest causes.

Options:
Coccidiomycosis

M
MD/MS-2016

18.Question
Atrophy of zona fasciculate of adrenal cortex due to hypophysectomy results in deficiency of which of the following hormone?

Options:
Mineralocorticoids

Options:
All of these

Options:
Androgen

Options:
Catecholamines

Options:
Glucocorticoids
Correct:
Glucocorticoids are released dominantly by Zona Fasciculata.

M
MD/MS-2016

19.Question
All of the following statements regarding barret esophagus are correct EXCEPT:

Options:
Results from prolonged reflux esophagitis

Options:
Mucosa shows gastric metaplasia
Correct:
Barret esophagus: - Complication of GERD - Glandular metaplasia in distal Esophagus due to acid reflux - Its intestinal type metaplasia - Most common complication is ulceration with stricture formation - Dysplasia leading to Adenocarcinoma

Options:
Metaplasia is characterized by presence of goblet cells and acid mucin on alcian blue stain

Options:
It is a precancerous lesion that gives rise to adenocarcinoma

Options:
It is related to H. Pyloric

M
MD/MS-2016

20.Question
Breast atrophy occurs due to:

Options:
Decrease estrogen level

Options:
Decrease progesterone level

Options:
Both a & b
Correct:
Estrogen is involved in the growth of Ducts and Stroma while Progesterone in development of Lobules and alveoli of breast.

Options:
None of these

Options:
Decrease LHRH level

M
MD/MS-2016

21.Question
Vinylchloride gives rise to:

Options:
Skin cancer

Options:
Lung cancer

Options:
Bladder cancer

Options:
Angiosarcoma of liver
Correct:
Vinylchloride can cause Angiosarcoma of liver.

Options:
Blood cancer

M
MD/MS-2016

22.Question
The causative organism of ludwing angina is:

Options:
Staphylococcus aureus

Options:
Streptococcus viridian

Options:
Streptococcus pyogenes
Correct:
Ludwig angina is cellulitis of floor of mouth caused by Streptococcus Pyogenes.

Options:
Streptococcus agalactiae

Options:
None of these

M
MD/MS-2016

23.Question
Enteropeptidase enzyme deficiency causes unavailability of which of the following enzymes in intestine during digestion?

Options:
Trypsin
Correct:
Enteropeptidase or Enterokinase is synthesized by brush border cells of small intestine, it converts the Trypsinogen into Trypsin and thus initiates the cascade of proteopytic activity in gut.

Options:
Amylase

Options:
Lipase

Options:
Elastase

Options:
Peroxidase

M
MD/MS-2016

Question
Compare to HMWH heparin, enoxaparin is:

Options:
Can be used without monitoring of APTT
Correct:
As Enoxaparin is LMWH, so does not need monitoring by APTT during treatment. It is long acting and has less complications as compare to HMWH.

Options:
Has a shorter durations of action

Options:
Is more likely to be given intravenously

Options:
Is more likely to cause thrombosis and thrombocytopenia

Options:
All of above

M
MD/MS-2016

Question
The anti-caogulant activity of warfarin can be accentuated by all of the following EXCEPT:

Options:
Rifampicin
Correct:
As Rifampacin is P450 inducer so will decrease action of warfarin.

Options:
Aspirin

Options:
Phenylbutazon

Options:
Cimetidine

Options:
None of the above

M
MD/MS-2016

Question
Aspirin prolongs bleeding time by inhibiting the synthesis of:

Options:
Clotting factors in liver

Options:
Prostacyclin in vascular endothelium

Options:
cAMP is platelets

Options:
Thromboxane A2 in platelets
Correct:
Aspirin irreversibly blocks the action of platelets by inhibiting the production of thromboxane A2

Options:
Inhibiting factor VII

M
MD/MS-2016

Question
Celiac artery supplies all of the following organs EXCEPT:

Options:
Liver

Options:
Spleen

Options:
Pancreas

Options:
Jejunum
Correct:
Celiac artery is artery of FOREGUT and its derivatives.

Options:
Gall bladder

M
MD/MS-2016

28.Question
All of the following are complications of total parenteral nutrition, EXCEPT:

Options:
Hypoglycemia

Options:
Fluid overload

Options:
Excess of folate and zinc
Correct:
Chronic def. syndromes during TPN cause def. of essential fatty acids, zinc, minerals and trace elements.

Options:
Fatty liver

Options:
Gall bladder stasis and biliary sludging

M
MD/MS-2016

29.Question
All of the following are true regarding gall bladder EXCEPT:

Options:
Peritoneum completely surrounds the round fundus of gall bladder

Options:
Lies in gall bladder fossa on visceral surface of (R) lobe of liver

Options:
Quadrate lobe on (R) side of gall bladder fossa
Correct:
Fundus is the wide end of gall bladder projecting from infection. Border of liver and usually located at the tip of 9th costal cartilage in midclavicular line and its completely surrounded by peritoneum, Quadrate lobe lies on the left of gall bladder fossa. Body lies anteriosuperior to duodenum.

Options:
Body lies anterior to duodenum

Options:
None of these

M
MD/MS-2016

30.Question
Lymphatic drainage of cervix include all of the following EXCEPT:

Options:
Internal iliac lymph nodes

Options:
Superficial inguinal nodes
Correct:
Cervix lymphatics: Main Internal iliac and some external plus sacreal LN.Superficial inguinal LN drain part of uterus where round ligament is attached.

Options:
External iliac lymph nodes

Options:
Sacral lymph nodes

Options:
None of these

M
MD/MS-2016

31.Question
Left Anterior descending artery in heart is accompained by:

Options:
Small cardiac vein

Options:
Middle cardiac vein

Options:
Great cardiac vein
Correct:
LAD is accompained by Great cardiac vein in anterior interventricular groove. Small cardiac vein accompaines right marginal branch of RCA. Middle cardiac vein accompanies the Posterior descending artery in post. Interventricular groove.

Options:
Ant cardiac vein

Options:
Superior cardiac vein

M
MD/MS-2016

32.Question
The branch of internal iliac which remains in true pelvis is:

Options:
Obturator artery

Options:
Internal pudendal artery

Options:
Inferior gluteal artery

Options:
Lateral sacral artery
Correct:
Obturator artery passes through obturator foramen and supplies in meidal compartment of thigh. Internal pudendal artery is the artery of perinum so leaves the pelvis through greater sciatic foramen, reenters through lesser sciatic foramen and then traverses the pundendal canal and enters in perineum to supply it. Inferior gluteal artery enters in buttock through greater sciatic foramen below the piriformis.

Options:
External gluteal artery

M
MD/MS-2016

33.Question
The following nerve can be damaged during apendecetomy:

Options:
Iliohypogastric
Correct:
Iliohypogastric during appendectomy and ilioinguinal during hernioraphy.

Options:
Ilioinguinal

Options:
Lateral femoral cut. nerve

Options:
Genitofemoral nerve

Options:
puedendal nerve

M
MD/MS-2016

34.Question
Which to the following prostaglandin mediates pain:

Options:
PGE2
Correct:
Pain in mediated by PGE2 and substance P.

Options:
PDG2

Options:
PGI2

Options:
PGF2

Options:
PDA2

M
MD/MS-2016

35.Question
Nicotinic acid deficiency causes:

Options:
Beri beri

Options:
Wernicke - korsakoff synd

Options:
Glossitis

Options:
Pellagra
Correct:
Nicotinic acid (Vit.B3/Niacin) deficiency causes PELLAGRA which is characterized by 3D i.e. Dermatitis, Dementia, Diarrhea.

Options:
Neuropathy

M
MD/MS-2016

36.Question
Which of the following is most common caused of cardiogenic shock?

Options:
Acute massive pulmonary embolus

Options:
Pericardial tamponade

Options:
Sudden onset valuvlar regurgitation

Options:
Myocardial infarction
Correct:
Most common cause of cardiogenic shock is acute massive M.I.

Options:
Atrial fibrillation

M
MD/MS-2016

37.Question
Which one is the most important test in diagnosis of cardiogenic shock?

Options:
CVP

Options:
PCWP
Correct:
Hemodynamic parameters of Cardiogenic shock: * CO Low * PCWP High (differentiates from other shocks) * SVR High

Options:
Blood pressure

Options:
ECG

Options:
Holter monitoring

M
MD/MS-2016

38.Question
All of the following muscles push towards opposite side EXCEPT:

Options:
Genioglossus

Options:
Pterygoids

Options:
Sternocleidomastoid

Options:
Muscle of soft palate
Correct:
Muscles of soft palate are pulling muscles that is why when they contract UVULA moves to healthy side or moves away from diseased side.

Options:
None of these

M
MD/MS-2016

39.Question
Micturition reflex center is situated in:

Options:
L2, L3, L4 segments

Options:
L5, L1

Options:
S2, S3, S4
Correct:
Micturition reflex center at the level of spinal cord is in S2, S3, S4 (best S2, S3) and at the level of Brain Stem its located in Rostral Pons (Barrington"s center)

Options:
L1, L2

Options:
T12, L1

M
MD/MS-2016

40.Question
Which vessel is most commonly used in CABG?

Options:
Long saphenous vein
Correct:
Reversed long saphenous graft is most commonly used for CABG.

Options:
Left internal mammary artery

Options:
Cephalic vein

Options:
Radial artery

Options:
Ulnar artery

M
MD/MS-2016

41.Question
All of the following are rotator cuff muscles EXCEPT:

Options:
Supraspinatus

Options:
Infraspinatus

Options:
Teres minor

Options:
Teres major
Correct:
Rotator cuff muscles: SITS - Supraspinatus - Infraspinatus - Teres minor - Subscapularis

Options:
Subscapularis

M
MD/MS-2016

42.Question
Which antithyroid drug is safe in pregnancy?

Options:
Propylthiouracil
Correct:
As PTU can’t cross placenta so it’s the safest anti thyroid drug during pregnancy.

Options:
Methimazole

Options:
Iodide

Options:
Radioactive iodine

Options:
Beta blocker

M
MD/MS-2016

43.Question
Propylthiouracil acts by:

Options:
Inhibition of iodination of tyrosyl residue on thyroglobulin

Options:
Blocking of coupling of MIT and DIT

Options:
Inhibiting proteolytic release of T3 and T4 from thyroglobulin

Options:
a & b
Correct:
PTU: * Sulphur containing thioamide * Blocks iodination of Tyrosine * Blocks coupling as well * Doesnott inhibit release of preformed hormones so action is slow (3-4 weeks) * Safe drug during pregnancy and lactation * Skin rash is most common side effect but can cause agranulocytosis and hypoprothrombinemia and liver dysfunction.

Options:
Acting centrally on CNS

M
MD/MS-2016

44.Question
Which of the following anti thyroid drugs is used for the reduction of vascularity of thyroid gland preoperatively?

Options:
Propylthiouracil

Options:
Methimazole

Options:
Iodide
Correct:
Drug of choice for the immediate preparation of hyperthyroid patient is Iodide.

Options:
Radioactive iodine

Options:
Beta blocker

M
MD/MS-2016

45.Question
Which of the following vessel will have the highest blood pressure in a standing person?

Options:
Femoral artery

Options:
Dorsalis pedis artery
Correct:
Farthest the artery below the heart, highest the blood pressure.

Options:
Radial artery

Options:
Cerebral artery

Options:
Carotid artery

M
MD/MS-2016

46.Question
Pulmonary resistance decreases in:

Options:
Exercise
Correct:
Hypoxia causes pulmonary vasoconstriction so increases the resistance while exercise decreases the resistance by causing vasodilatation probably due to high PAO2 (alvelar) and release of Beta adrenergic catecholamines.

Options:
Expiration

Options:
Hypoxia

Options:
Haemrrhage

Options:
Hypertension

M
MD/MS-2016

47.Question
Clomiphene citrate causes ovulation by:

Options:
Blocking signal receptions in pituitary
Correct:
CLOMIPHENE induces Ovulation - None steroidal compound - Selectively blocks Estrogen receptors in Pituitary - Thus reduces Negative Feedback and increase FSH and LH which cause Ovulation.

Options:
Increases FSH & LH output

Options:
Increase growth hormone

Options:
Decreases FSH & LH

Options:
Increase estrogen

M
MD/MS-2016

48.Question
Red tongue can occur in all of the following conditions EXCEPT:

Options:
Vit-B12 deficiency

Options:
Folic acid

Options:
Riboflavin acid

Options:
Iron

Options:
Vit-B6
Correct:
D/D of Red Tongue: * Vit deficiency like B6, B12, Riboflavin * Plummer vinson syndrome * Amyloidosis * Kawasaki disease

M
MD/MS-2016

49.Question
Action of Vit-D on bone is:

Options:
Bone absorption

Options:
Bone mineralization

Options:
Both a & b
Correct:
Vit-D under normal conditions deposit calcium and phosphate in bone and at abnormally high activity level it causes bone resorption and releases calcium and phosphate.

Options:
Bone resorption

Options:
None of above

M
MD/MS-2016

50.Question
Alpha-2 adrenergic receptors are located on:

Options:
Pupillary dilator muscle

Options:
Pilomotor smooth muscle

Options:
Heart

Options:
Fat cells
Correct:
Alpha-2 receptors on fat cells inhibit lipolysis.

Options:
All of above

M
MD/MS-2016

51.Question
Sympathetic alpha adrenergic stimulation causes all of the following EXCEPT:

Options:
Mydriasis

Options:
Stimulation of glycogenolysis

Options:
Bladder sphincter contraction

Options:
Stimulation of lipolsys
Correct:
Sympathetic alpha adrenergic stimulation causes all of given except Stimulation of lipolysis.

Options:
None of above

M
MD/MS-2016

52.Question
In going from a lying down to an upright position, the change in pressure will be greatest in which of the following vessel:

Options:
Aorta

Options:
Pulmonary artery

Options:
Femoral artery
Correct:
Highest pressure will develop in femoral artery.

Options:
Sub clavian artery

Options:
Pulmonary vein

M
MD/MS-2016

53.Question
Muscles supplied by hypoglossal nerve arise from:

Options:
Pharynged arch 1

Options:
Pharynged arch 2

Options:
Pharynged arch 3

Options:
Occipital somites
Correct:
XII CN is not the nerve of Pharyngeal arches. It supplies muscles of tongue which are derivative of occipital somites.

Options:
Cervical somites

M
MD/MS-2016

54.Question
Fracture of neck of fibula causes palsy of:

Options:
Femoral nerve

Options:
Superficial peroneal

Options:
Deep peroneal nerve

Options:
Tibial nerve

Options:
Common peroneal nerve
Correct:
Common peroneal nerve wraps around the neck of fibula and this is the most common site where it get damaged especially in fracture situtation.

M
MD/MS-2016

55.Question
Complete depolarization of heart is shown by:

Options:
U-wave

Options:
ST segment

Options:
QT segment

Options:
PR segment

Options:
QRS complex
Correct:
Complete depolarization of heart is represented by QRS complex in ECG.

M
MD/MS-2016

56.Question
Which of the following transform into malignancy commonly:

Options:
Leukoplakia
Correct:
Leukoplakia is the most common pre-malignant lesion of oral cavity.

Options:
Keratoacanthoma

Options:
Seborrheic keratosis

Options:
Freckle

Options:
All of above

M
MD/MS-2016

57.Question
In right colon surgery which of the following may involve?

Options:
Aorta

Options:
Inferior vena cava
Correct:
While removing the Ca caecum or ascending colon, the structures at risk are IVC and right ureter.

Options:
Spleen

Options:
Pancreas

Options:
Subclavian artery

M
MD/MS-2016

58.Question
Infection from 1st web space between thumb and first finger goes to which lymph node?

Options:
Clavicular

Options:
Supraclavicular

Options:
Epitrochlear

Options:
Axillary

Options:
Infraclavicular
Correct:
Lymphatics from first web space of hand travel with cephalic vein and drain into infraclavicular group of LN.

M
MD/MS-2016

59.Question
Lateral horn of spinal cord exists in:

Options:
Thoracic spine
Correct:
Lateral horn represents the sympathetic motor control center and located from T1 to L2/L3.

Options:
Cervical spine

Options:
Lumbar Spine

Options:
Sacral spine

Options:
All of these

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