Dept. of Microbiology & Biotechnology NUST

How do immune cells interact with fungi? 🔬What's new in the world of dengue virus vaccines? 💉

Find out in this week's ASM Journal Highlights! ✨⬇️

🧫The gut is the main reservoir for disseminated fungal infections. In this review, learn how specific immune cell types and effectors interact with fungi to limit their colonization or pathogenic potential. https://asm.social/1QN

🚰Researchers studied drinking water biofilms to reveal the impact of operational variations in pH and free chlorine concentration on the biofilm microbiome, as well as biofilm susceptibility to invasion by the coliform Serratia fonticola. : https://asm.social/1QO

🦠 Is everything everywhere? A new hands-on activity presented in engages undergraduates with fundamental microbial dispersal and biogeography concepts while also building quantitative reasoning and teamwork skills. https://asm.social/1QM

🦟Dengue virus infects 400 million people worldwide. A new virus-like particle vaccine induces high levels of neutralizing antibodies & reduces dengue replication in non-human primates, indicating it may be a promising vaccine candidate. : https://asm.social/1QL

🧬 The emerging pathogen Enterobacter cloacae expresses 2 type VI secretion systems (T6SS), which are directly activated by the major histone-like protein HU. Learn about the how this regulation affects T6SS-related phenotypes in : https://asm.social/1QK

Want more of the latest microbial sciences research? Stay tuned for the next !

What's new in the world of single-cell sequencing?💻 Which new compounds show promise for treating flavivirus and fungal infections? 💊

Check out this week's ASM Journal Highlights! ⬇️

🔬All the single cells...if you like it, put some virus on it! Using a single-cell approach to explore fundamental virology questions, researchers have sparked a revival of interest in single-cell virology with increased insights. : https://asm.social/1VS

🧫Zafirlukast, a pregnancy-safe leukotriene receptor antagonist, shows potent in vitro antiviral activity against several flaviviruses, including Zika virus, dengue virus and yellow fever virus, making it a promising therapeutic candidate. : https://asm.social/1VU

🍄When studying the mycorrhizosphere, the research community needs to adopt a holistic tripartite approach that includes plants, arbuscular mycorrhizal fungi and the microbial community. Read the review in : https://asm.social/1VW

🦴Bisphosphonates, which are approved to treat osteoporosis, enhance the antifungal activity of azoles in dematophytes (infect the skin, hair & nails) and other pathogenic molds; the combination could be fast-tracked for use in clinical therapy.
: https://asm.social/1VV

🦠C-di-AMP binds to a signal transduction protein, called DarA, in Bacillus subtilis. But what does DarA do? Research in suggests it is a central processing unit for the integration of osmotic with potassium and amino acid homeostasis. https://asm.social/1VT

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How do Pseudomonas aeruginosa infections impact skeletal muscle? 💪Could probiotics help in the management of gluten-related disorders? 🥐

Find the answers in this week's ASM Journal Highlights! ✨

🦠A copper-responsive molecule inhibits UPEC, the main cause of UTIs, as well as other bacteria of medical significance; the compound may be a viable alternative to antibiotics. https://asm.social/1WG

🧬Genetically engineering methanogenic archaea is difficult due to their unique physiology & limited genetic tools. However, recent advances hold promise for overcoming these obstacles. : https://asm.social/1WD

💪 Mitochondrial dysfunction in skeletal muscle is mediated by a P. aeruginosa quorum sensing transcription factor, which can be reversed via treatment with a mitochondrial-targeted peptide. : https://asm.social/1WF

🥪Researchers show that a novel probiotic preparation enhances gluten digestion & promotes gut microbiota functionality in adult volunteers. https://asm.social/1WE

🥼A highly structured undergraduate course, incorporating weekly student presentation of patient cases encompassing history taking, diagnosis & treatment, leads to content learning & improves desired skills specific for success in medical fields. : https://asm.social/1WH

For more of the latest research published in ASM Journals, visit: https://asm.social/1WI

And stay tuned for more !

Welcome to the official page of Dept. of Microbiology & Biotechnology (MBT) at ASAB - NUST. All updates, news, scientific literature and departmental activities of MBT will be posted here. You can also write scientific blogs on microbiology and biotechnology for this MBT page. 🦠🧬💊