The American Academy of Neurology is working to stimulate medical students’ interest in neurology. The AAN inaugurated the Student Interest Group in Neurology (SIGN) program in 1998, with the endorsement of the Association of University Professors of Neurology (AUPN) and the American Neurological Association (ANA). There are over 150 SIGN Organizations at medical schools throughout the world. The purpose of SIGN is to introduce medical students to the field of neurology by bringing them together with fellow students with similar interests through discussions by neurologists, patient presentations, seminars, journal clubs, learning materials, and arranged shadowings of neurologists in the workplace. Medical students become aware of opportunities, and participate in activities, related to the field of neurology, including opportunities for research, creating a new generation of neurologists and AAN members.