It is located on Taft Avenue at the corner of Padre Faura Street in Ermita, Manila, and was established on October 1, 1963. History
Former President of the Philippines Ramon Magsaysay was the first to envision a Science high school in the Philippines in his 1956 State of the Nation address where he underscored βthe great need of stepping up the development of fundamental and applied research in sc
ience and technology which has long been neglected.β
Taking action, the Philippine Congress passed Republic Act 1606 creating the National Science Development Board to work with the Science Foundation of the Philippines in advancing scientific and technological research. This was closely followed by Republic Act 2067, known as the Science Act of 1958 which proposed to integrate, coordinate, and intensify scientific and technological research and development to foster invention. In conjunction, the Department of Education implemented RA 1606 by issuing Department Orders 1 and 5, series of 1958, for the launching of Science Talent Research. November 25, 1959 marked the evolution of the first pilot science high school in Manila. Comprising 32 students screened through a competitive examination, this nucleus of a science high school had its beginnings in a single-storey building in Intramuros. On October 1, 1963, the Manila Science High School was born by virtue of Municipal Resolution 426 signed by Mayor Antonio J. Credit for the school's early success goes to the Manila Science High School Principal Augusto Alzona β the "Father of Manila Science High School". Modeled after the Bronx High School of Science, the special science curriculum is designed to meet the needs of scholars gifted in science and mathematics. However, opportunities, training, and experiences in varied fields are also available.