UST-Allergy and Immunology Laboratory

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31/07/2026
29/07/2026
Andrea delivered a paper showing that the recombinant S. boulardii engineered to express Suip2 hypoallergen, could resto...
14/07/2026

Andrea delivered a paper showing that the recombinant S. boulardii engineered to express Suip2 hypoallergen, could restore dysbiosis in the gut microbiota of BALB/c mice with chronic asthma and mitigate allergic inflammation.

Aiyahnna presented evidence showing the increased expression of Th1 genes TBX21, IL-12, and IL-2, and decreased expressi...
14/07/2026

Aiyahnna presented evidence showing the increased expression of Th1 genes TBX21, IL-12, and IL-2, and decreased expression of Th2 genes GATA-3, IL-33, TSLP, and CCL27 in BALB/c mice treated with the hypoallergen Der p 2/1S expressed in the yeast S. boulardii. This paper suggest the potential of the genetically modified S. boulardii as an oral prophylaxis for allergic dermatitis.

Erika showed that crustaceans such as shrimps, crabs, and lobsters contain allergens that trigger food allergies in Fili...
10/07/2026

Erika showed that crustaceans such as shrimps, crabs, and lobsters contain allergens that trigger food allergies in Filipino atopic patients.

Ram successfully demonstrated the molecular cloning and recombinant protein expression of a new allergen from the house ...
10/07/2026

Ram successfully demonstrated the molecular cloning and recombinant protein expression of a new allergen from the house dust mite Suidasia pontifica (Sp), providing further evidence of the clinical relevance of Sp as an important source of allergens that trigger allergic symptoms in Filipino atopic patients.

Andrea demonstrated that four allergen-coding sequences from the house dust mite Suidasia pontifica (Sp) contain linear ...
10/07/2026

Andrea demonstrated that four allergen-coding sequences from the house dust mite Suidasia pontifica (Sp) contain linear B-cell epitopes capable of binding to the complementarity-determining regions (CDRs) of human IgE. These findings provide strong evidence supporting the identification of novel S. pontifica allergens.

Julia provided evidence that oral administration of the genetically engineered yeast S. boulardii, which expresses the D...
10/07/2026

Julia provided evidence that oral administration of the genetically engineered yeast S. boulardii, which expresses the Derp2/1S hypoallergen, could suppress allergic asthma symptoms in allergic asthma mouse models

Jabez presented the reduced IgE reactivity of the recombinant Derp1/2 Mosaic hypoallergen (compared to the recombinant D...
10/07/2026

Jabez presented the reduced IgE reactivity of the recombinant Derp1/2 Mosaic hypoallergen (compared to the recombinant Der1/2 Fusion allergen), underscoring its utility as a potential immunotherapeutic reagent for house dust mite allergy.

We SAILed to the 48th NAST ASM to share 5 poster presentations.
08/07/2026

We SAILed to the 48th NAST ASM to share 5 poster presentations.

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