Manipal Pharmacology

Beta-adrenoceptors (both β1 and β2) are coupled to Gs-proteins, they are very similar, yet β1 increases the contractility of heart muscles but β2 relaxes the muscles in the blood vessels. Can anyone explain why, how?
---Question asked by Anmol Lamichhane II Sem.

Non-pharmacological measures for management of HTN. This is posted on the demand of II Sem MBBS students

Lifestyle management of hypertension - Australian Prescriber Recently updated Australian guidelines recommend that advice on smoking, nutrition, alcohol use, physical activity and body weight should be part of routine management of hypertension for all patients, regardless of drug therapy.

Is there a place for thiazide diuretics in the management of hypertension? - Australian Prescriber Before the introduction of antihypertensive drugs in the 1940s, one of the few effective approaches to treating high blood pressure was severe restriction of dietary salt intake.

Drug that may cause tachycardia is:
a. Verapamil
b. Propranolol
c. Diltiazem
d. Nifedipine

FALSE about bradykinin
a. Causes natriuresis contributing to drop in BP
b. Causes vasodilation contributing to drop in BP
c. Gets activated by kininase II
d. ACE metabolizes it

An elderly hypertensive has DM and bilateral renal artery stenosis. The best management is:
a. Enalapril
b. Thiazides
c. Verapamil
d. Beta blockers

Choose the combination that can be prescribed in patients with HTN
a. Verapamil + Propanol
b. Spironolactone + ACEI
c. ACEI + thiazides
d. Digoxin + Verapamil

http://jama.jamanetwork.com/article.aspx?articleid=1936801

Low-Dose Aspirin for Cardiovascular Event Prevention Importance Prevention of atherosclerotic cardiovascular diseases is an important public health priority in Japan due to an aging population.Objective To determine whether daily, low-dose aspirin reduces the incidence of cardiovascular events in older Japanese patients with multiple...

very informative article
http://www.fda.gov/Drugs/ResourcesForYou/Consumers/ucm390574.htm

Use of Aspirin for Primary Prevention of Heart Attack and Stroke Use of Aspirin for Primary Prevention of Heart Attack and Stroke [05/02/2014] Cardiovascular disease, including heart disease and stroke, affects tens of millions of people in the United States. Consumers and patients who do not suffer from cardiovascular disease sometimes consider taking aspirin t…

nice article on BP monitoring
http://m.australianprescriber.com/magazine/38/1/16/9

A Relaxed Mind, A Peaceful Soul, A Joyful Spirit, A Healthy Body & Heart full of Love..All these are my Prayers for my friends, and students.. Wish a you all a Happy New Year 2015...... SUDESH GYAWALI