HSØ Core Facility for Structural Biology

HSØ Core Facility for Structural Biology The Core Facility for Structural Biology offers services and access to technologies for researchers

The core facility provides services to all research groups affiliated with institutions belonging to the Helse Sør-Øst region. We also serve universities and university colleges in the region. Our portfolio includes protein crystallization, 3-dimensional structure determination of proteins at atomic resolution by X-ray crystallography or in-solution BioSAXS studies of protein complexes, various methods for protein-protein and protein-ligand interaction studies (MST, SPR, ITC), as well as 3D modeling of proteins. We also advice and assist collaborators with molecular biology, including cloning, protein expression and purification. The core facility also provides services within structural bioinformatics. Due to the challenging nature of protein crystallization and 3D structure determination of biological macromolecules, most projects are carried out as a collaborative research project with co-authorship. However, for a limited user-fee, we also provide access to instruments and technologies for experienced users after prior agreement. The Structural Biology Core Facility collaborates closely with the Bioinformatics Core Facility.

01/08/2016

Paper with contribution from our Core Facility published in PNAS today

07/07/2016

MST data collected in our facility is part of accepted PNAS paper. Congratulations to Xisong Ke and co-workers!

Adresse

MBK, B1. 3049/Rikshospitalet, Sognsvannsveien 20
Oslo
0424

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