Department of Pharmacognosy, Obafemi Awolowo University, Ile-Ife, Nigeria

Departmental Seminar (Physical/Virtual) - Department of Pharmacognosy, Obafemi Awolowo University, Ile-Ife

TOPIC - African Traditional Medicine Day: The contribution of Uvaria chamae (Annonaceae) to traditional medicine

Presenter: Dr. A. O. Adepiti, (Obafemi Awolowo University, Department of Pharmacognosy).
Tuesday, 31st August 2021
9:00am (West Africa Standard Time - Lagos)

Physical Venue: Board Room, Faculty of Pharmacy (Phase I), Obafemi Awolowo University, Ile-Ile.
Virtual Venue: Join with Google Meet link - https://meet.google.com/sra-uewq-hnr

ABSTRACT:
The African Traditional Medicine (TM) Day of August 31 2021, draws attention to the role of Africa’s rich repository of medicinal plants to improve well-being. In the last two decades, there have been much progress in the research into and practice of TM, which include the development of herbal pharmacopoeiae in some countries. One of such medicinal plants is Uvaria chamae (Annonaceae), a shrub prevalent in the rain forests of West and Central Africa, which has antimalarial and anti-trypanosomal activities, among others. However, the anatomical evaluation of the plant has not been reported. Therefore, this study aimed to determine the botanical characters of the leaf and root of the plant in order to establish pharmacopoeial parameters for quality control.
The fresh leaf and root of Uvaria chamae P. Beauv (Annonaceae) were collected and authenticated. Organoleptic evaluation of the whole drugs and microscopy of the powder were carried out according to standard methods. Physicochemical properties such as moisture content, ash and extractive values were determined. Transverse section of the leaf as well as radial and tangential longitudinal sections of the root were carried out.
In the leaf and root, values for the total ash were 9.6 and 9.7%, loss on drying were 8.8 and 8.1%, alcohol-extractive were 3.5 and 0.8 % and water-extractive were 4.5 and 1.3 %, respectively. The midrib of the leaf was dorsiventral and the cuticle striated. Paracytic stomata present on the abaxial surface but stomata absent on the adaxial surface. The root had prismatic calcium oxalate crystals and collateral vascular bundle.
The macro- and micro- scopic features would characterise the plant and also aid the quality control of U. chamae-containing medicinal products that are used in TM.

Departmental Seminar (Physical/Virtual) - Department of Pharmacognosy, Obafemi Awolowo University, Ile-Ife

TOPIC - The Search for Larvicidal Compounds from Medicinal Plants: Our Contribution.

Presenter: Dr. Famuyiwa, Funmilayo Gladys. (Obafemi Awolowo University, Department of Pharmacognosy).

Tuesday, 27th July 2021
9:00am West Africa Standard Time - Lagos

*Physical Venue:* Board Room, Faculty of Pharmacy (Phase I), Obafemi Awolowo University, Ile-Ile.
*Virtual Venue: Join with Google Meet link -* https://meet.google.com/sra-uewq-hnr

*ABSTRACT:*
Controlling mosquito populations at all stages of its development, especially the larval stage, had been endorsed by the World Health Organisation as an important means of preventing and eradicating the various diseases they transmit. However the development of resistance by this vector to available larvicides makes the search for and the discovery of more effective ones that could break the mosquitoes life cycle imperative. Extracts and constituents of medicinal plants have proven to be effective, biodegradable and with low mammalian toxicity. Also the multi-component nature of the extracts prevents induction of resistance to them. Hence, the continued search for safer plant larvicides among ethnomedicinal plants.
Forty-eight Nigerian plants with ethnomedicinal claims of febrifuge, anti-malarial, insecticidal and insect repellent activities were collected, authenticated, dried, powdered and extracted with methanol. The resulting extract of each plant was tested for larvicidal activities against the fourth instar larvae of Aedes aegypti and Culex quinquefasciatus according to WHO guidelines of 2006. The active extracts were identified, suspended in water and successively partitioned into n-hexane, dichloromethane and ethylacetate. Each of the partitioned fractions was similarly tested to identify the most active for each plant. The most active partitioned fractions of Xylopia aethiopica and Blighia sapida were subjected to series of chromatographic separations and the active compounds were isolated. The spectroscopic analyses (nuclear magnetic resonance, infrared and mass spectroscopy) of the isolated compounds were carried out and the structures were elucidated.

Kaur-16-en-19-oic acid and xylopic acid from X. aethiopica fruit; friedelin and α-amyrin from B. sapida were identified as their larvicidal compounds. These compounds are more active than Endosulphan the positive control used. Our efforts on the other identified active extracts will be discussed at the seminar.

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Send Off/Lecture In Honour of JOSEPH ADETUNJI ALADESANMI, Professor of Pharmacognosy*
Monday, May 24, 2021 • 10:00 AM – 12:00 PM
You can also connect via
Google Meet joining info link: https://meet.google.com/zmz-cfog-aqr
Or dial: +1 503-908-2093 PIN: 172 155 433 #

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Pharmacognosy Departmental Seminar (Virtual)
Topic: Evaluation of the Antimalarial Activity of Pleioceras barteri (Apocynaceae) Baill. in Mice
Presenter: Mr. A. O. Adegeye
*10am, Monday 7th September 2020*
Join with Google Meet:
https://meet.google.com/nej-hmod-vkm

CVS Pharmacy El Ezaby Pharmacy Aster Pharmacy Pharmacy Times صيدليات سيف - SEIF Pharmacies Pharmacognosy.Medicinal plants International Journal of Pharmacognosy - IJP Pharmacognosy Dept. Tanta University Faculty of pharmacy Faculty of Pharmacy - Alexandria University Faculty of Pharmacy (ERU)

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TOPIC: STUDIES ON NIGERIAN MONOAMINE OXIDASE INHIBITING PLANT EXTRACTS AND THEIR PRODUCTS

WEEKLY ACADEMIC SEMINAR OF DEPARTMENT OF PHARMACOGNOSY,
FACULTY OF PHARMACY,
OBAFEMI AWOLOWO UNIVERSITY, ILE-IFE

PRESENTER: Olayemi, U. I.

DATE: Tuesday, 29 October, 2019.

ABSTRACT
Monoamine oxidase (MAO) is a mitochondrial flavoenzyme involved in the oxidative
deamination of amines such as neurotransmitters like serotonin, norepinephrine, dopamine
etc. Synaptic modulation of these neurotransmitters by MAO is important for the expression
of mood and emotions and the control of motor and cognitive functions.Unfortunately, the oxidation of amines by MAO produces neurotoxic by-products implicated
in some disorders of the central nervous system (CNS) such as Parkinson's disease (PD),
Alzheimer's disease (AD), depression, ete.PD and AD are the most common neurodegenerative diseases affecting about 4 % of people
worldwide above 65 years, while about 800,000 people die from suicidal depression annually
worldwide.Synthetic MAO inhibitors are used in the management of these disorders but with restrictions
and limitations due to severe side effects. This challenge has sparked interest in natural MAO
inhibitors from medicinal plants.The seminar will further address the use of some Nigerian plants with potentials of MAO
inhibitory activity in the management of disorders of the CNS.

Pictures from our just concluded Departmental seminar... Presented by Olawumi, Oluwatosin Funke, a new PG student in the department who discussed her undergraduate project work.
International Journal of Pharmacognosy - IJP Pharmacy Hub Nigeria Pharmacognosy_PvP Pharmacognosy department, Faculty of Pharmacy, Helwan University All about Pharmacognosy Pharmacognosy Dept. Tanta University Pharmacognosy Department ERU Department of Pharmacology and Pharmacognosy, University of Nairobi Pharmacognosy University of Sydney BRASA - Brazilian Student Association at Rice University

In moment, we will start off with the live streaming for the send off program of our former staff...
Fadare, O. O
Gbadamosi, O. O
Oluitan, J. O.

Pharmacognosy is the study of plants or other natural sources as a possible source of drugs.
"This is the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources" - The American Society of Pharmacognosy