25/03/2021
A Map of the Brain
Writers who describe the brain tend to use the phrase “architecture of the brain.” We can see why. To use the term “architecture” suggests that like a skyscraper or an urban piece constituted of concrete slab, the brain is a complex system of beams, columns and walls that rests on the most fundamental elements of graph theory or plane geometry with a dozen or so engineering equations intertwined.
But that’s too fancy for our taste. If we have to sound hip about the
brain, we’d much rather compare it to the Los Angeles freeway during rush hour. Now that’s much better, isn’t it? You have movement, dynamism and complexity – so unlike a static architectural production, cold and unforgiving.
If a surgeon peeled off the skin and hair off a human being to expose his brain, we would probably reel and turn away from such a grotesque sight – lumps of raw ground beef held together by a fragile piece of glue. If we had the courage to look inside, however, we’d probably be entranced, marveling at how it does sort of resemble the LA freeway. To be able to see the brain in action would be like watching shooting stars and passing comets in the universe.
Peeking into the Brain
If you read about the brain, you’ll come across terms that you may have already learned in high school, so this section will be a quick review of the parts of the brain.
To better explain what the brain consists of and which parts are
responsible for certain functions, we’ll take a hypothetical situation. Imagine that you’re in the cockpit of a 747, seated beside the chief pilot. In this scene, you are an invisible observer; the pilot does not know you’re there. He has an emergency situation to deal with but for as long as there is no immediate danger he sees no need to announce it to the passengers.
The pilot has just received news that there is a deadly storm heading towards the aircraft. He has about 20 minutes to think of a set of maneuvers to either (a) avoid the path of the storm or (b) maintain his present course so he could land at the intended destination on time.
As he communicates with the air traffic controllers, he begins to realize the seriousness of the situation and his mind literally goes on overdrive. There are 274 lives he is responsible for. The kinds of decisions he makes will either save those lives or cut them short. The traffic controller’s words were “you can try to weather the storm, but it has a wind velocity which we’re not sure the aircraft can withstand.”
The pilot’s brain goes to work. Right beneath each statement is the part of the brain that’s working (in bold) as he’s thinking and deciding – and reacting.
The pilot is informed he’s got 20 minutes to make a decision: he either changes his trajectory completely or stays the course hoping the aircraft is strong enough to withstand battering from the storm. He’s breathing faster and his heart rate is pounding: HINDBRAIN
He steers the plane a little to the left, presses some controls on the panel to increase altitude. He does these steps almost by rote: CEREBELLUM (located in the hindbrain)
His eyes are focused in the vast darkness before him. He blinks
constantly making sure his path is clear: MIDBRAIN
At this point, the pilot is analyzing his fuel capacity. If he changes trajectory to avoid the storm completely, that means a three hour delay. Does he have sufficient fuel? His mind races as he tries to remember other emergency procedures. What are the pros and cons? He recalled a fellow pilot who had to make the same kind of decision and almost didn’t make it: FOREBRAIN
Pilot is now arguing with himself. He keeps saying “what if” and then answers it himself. His abstract reasoning has never been this sharp before.
These emergencies are making him think at double the speed. Looking for answers…imagining the alternatives…evaluating scenario A versus scenario B: RIGHT HEMISPHERE (located in the cerebrum)
Pilot re-establishes communication with air traffic control. “I’ll change course.” He outlines his plan in detail, talks to the control tower and assures them he has sufficient fuel: LEFT HEMISPHERE (located in the cerebrum)
Pilot thinks about his wife back home. If he doesn’t make it, did he update his will? If he makes it, he’ll ask for a month’s leave, take his wife to the Caribbean for a much needed vacation. It’s been a heck of a month, he says to himself. They hardly saw each other. Is she seeing someone else? FRONTAL LOBE
Two hours and twenty minutes later, pilot taxis into runway 8B. “Ladies and gentlemen, welcome home. We apologize for the delay. We needed to change direction because of a storm brewing over Hokkaido Island in Japan.
We’ll be pleased to make alternatives for those who have been inconvenienced by this delay. Thank you for flying with Brainwave Airlines, your thinking airline.”
Pilot walks into the pilot executive lounge and is greeted by a warm round of applause. “What’s this, he asks. “Your reward for thinking and planning well”, says his boss. Someone told us you love sushi and kimchi – well, here’s a plate. No charge. Enjoy it.” His colleagues shake his hand as they exit the lounge saying “well done, kiddo. Thank goodness, cabin air didn’t shrink your brain. Brilliant maneuvering!” Seeing the sushi, he had almost forgotten how famished he was. He sat down and devoured the meal, relishing every morsel. The best meal he’s had in months! PARIETAL LOBE
As he drives to his hotel, he made a note that he’d have to reconstruct the events of the night and input it into the database of the emergency manual for pilots. He’ll do that first thing in the morning while it’s still fresh in his mind and can remember every detail and maneuver he executed in the last three hours: HIPPOCAMPUS
End of film clip. Let’s summarize what we’ve just learned about the components of the brain.
One incontestable fact we must accept: the brain is the most complex part of the human body.[3] We’d like to add our bit: some brains are more complex than others; this is why we have individuals who are more complicated than others and hence difficult to understand.
The brain weighs only three pounds, but this lightweight, mass holds our intelligence, puts some sense to all five senses, sets our bodies in motion and directs our behavior. Taking all the brains of our fellow human beings and putting them together would enable us to define civilization and encapsulate the story of humanity.
Since much knowledge has been gained from the study of the brain in the last two to three decades, Steven Pinker says that the United States government thought it appropriate to designate the 1990s as the Decade of the Brain. He quips, “But there will never be a Decade of the Pancreas.”[4] This is because the brain enjoys special status. That special status resides in the brain’s ability to make humans see, feel, think, choose and act – and calls it information processing.[5]
Just as the cell is the basic unit of human life, the brain is made up of three major units:
Forebrain
Midbrain
Hindbrain
Forebrain - this is the most highly developed section of the brain. It contains the cerebrum and other structures. When people look at pictures of the brain, the first thing they usually see is the cerebrum which is located at the top of the brain where most of a person’s intellectual activities come from. It houses your memories, makes you capable of planning, imagining and thinking. It is the part that assists you in recognizing your friends and family, enjoying a movie and playing solitaire.
Midbrain – this is located in the topmost part of the brainstem and controls our eye movements and other voluntary movements.[6] If you recall our film clip, when the pilot kept blinking his eyes to look out in the dark skies and adjusting his glasses, his midbrain was called to task.
Hindbrain – you will find the hindbrain right above your spinal cord. This is where the cerebellum is located. It resembles a wrinkled ball of tissue. It is the hindbrain that directs the body’s respiratory and heart rates. It coordinates bodily reflexes and is also responsible for movements you make automatically or by rote. For example, when you play the violin or run a marathon, the cerebellum located in the hindbrain goes to work.
Looking deeper into the brain, we now focus on the cerebrum, which has two hemispheres. As we said earlier, the cerebrum is located in the forebrain.
These hemispheres are separated by a deep dividing line; this division does not prevent the two hemispheres from sending messages to and from each other.
They look similar in appearance but differ in their functions.
Hemispheres of the Brain
Left hemisphere – when an individual utters words, it is the left
hemisphere that is working.
Right hemisphere – when an individual engages in abstract reasoning or logic, it is the right hemisphere that enables him to practice these skills.
The brain and the body send signals to each other and when they do, these signals cross over. This means that the right hemisphere controls the left side of the body, while the left hemisphere controls the right side. Therefore, hen one side of the brain is affected or is hurt, the opposite side of the body is affected. To put it more clearly, if an individual has had a stroke in the right hemisphere of the brain, his left arm and leg are paralyzed.[7]
As we explore our thoughts and how they get processed in the brain, we will need to know about the brain’s other components. Note that each hemisphere is divided into sections – more commonly called lobes. These lobes – frontal, parietal, occipital and temporal - have their own respective functions.
Frontal lobes – there are two frontal lobes located behind the forehead.
When you sit down and make a shopping list, plan an itinerary or argue with your boss, these are the two lobes that enable you to perform these functions.
The frontal lobes are what the Neurological Institute of the NIH calls a “short term storage site”; that is, keeping one idea on standby while you weigh other ideas. The left frontal lobe is where you’ll find Broca’s area, which processes your thoughts into words.
Parietal lobes – remember our airline pilot who loved sushi and kimchi?
When he ate every bite and cleaned out his plate, his parietal lobes were at work. The pilot’s smell, texture and taste for sushi were processed by his parietal lobes and more specifically by the primary sensory areas. These areas are information receptors, especially when the information has to do with temperature, touch and taste. The parietal lobes, however, are not limited to taste and smell, but also process reading and arithmetic functions.
Occipital lobes – these lobes are located at the back of the brain. They receive images that the eyes see and send those images to be stored in the memory. If the occipital lobes are damaged, blindness can occur.
Temporal lobes – these are found in the visual areas of the brain and are located just underneath the parietal and frontal lobes. Are you a fan of Eminem? Do you swoon over Tom Jones when he sings “What’s New Pussycat?” Your temporal lobes are at work. The temporal lobes process information received by the ears; these lobes contribute to memory functions – including anything to do with music, as well as sensations associated with taste, sound, light and touch.
Venturing into the deeper recesses of the brain, we find three distinct components:
Hypothalamus
Thalamus
Hippocampus
The NIH describes these three parts as the “gatekeepers” that lie in between the spinal cord and the hemispheres of the brain. These three elements orchestrate our emotions and the manner in which we respond to such emotions.
Hypothalamus – this serves as the center of vital functions. It drags you out of bed, makes you nervous and your hands clammy when you’re about to break the news to your parents that you failed Physics, and it works every time you’re ecstatic, frustrated or raving mad.
Thalamus – the thalamus is located close to the hypothalamus and acts as a traffic coordinator between data to and from the spinal cord and the cerebrum.
Hippocampus – this component is small in size and yet acts as a warehouse of memories. It’s like the hard disk of your computer. It stores your files and then when you need them, retrieves them for you. It also has nerve cells that come in clusters called basal ganglia, responsible for triggering movement.
No discussion on the brain is complete without mentioning neurotransmitters. These are the chemical messengers of the brain that carry thoughts back and forth from cell to cell. The health of our brain depends to a significant degree on the proper balance of neurotransmitters. So when people are diagnosed with Alzheimer’s, it means that there is widespread death of brain cells. The brain is flesh and blood. This is one thing that people have to remember. It is NOT the mind. The brain is the organ and like any organ of the body, it needs nutrition and rest. The mind is WHO we are – the software that carries out the functions of the hardware – the brain.
Brain Neurotransmitters
Acetylcholine – this substance is the principal memory carrier. People with Alzheimer’s show lower levels of acetylcholine. It dictates if our muscles have to contract or make our glands secrete hormones.
GABA – this is gamma-aminobutyric acid and is referred to as a
neurotransmitter that inhibits because it calms down cells. It regulates muscle movements and is an essential part of the visual system. Epileptic and Huntington patients usually take drugs to increase GABA levels in the brain.
Serotonin – this is another inhibitory neurotransmitter that acts on blood vessels and promotes sleep and regulates the body’s temperature. Together with norepinephrine, it keeps individuals in a good mood. It is therefore likely that crankiness in older men and women have a biological basis. Out of 40 million Americans aged sixty five and older, more than six million could be candidates for depression, and most of them consider it as part of the aging process. Dr. Khalsa, however, says that it is possible to overcome shortages of these mood neurotransmitters through nutritional and pharmacological solutions.[8]
Dopamine – another neurotransmitter that influences mood and body reflexes. Examples of low dopamine levels are seen in Parkinson’s patients who suffer from rigid muscles and lose control over their movements. This indicates that dopamine levels have decreased in some segments of the brain.
Scientists have discovered at least 100 neurotransmitters and they all have their individual chemical activities. The above are some of the key neurotransmitters that preserve some of the more important functions of the brain.
In the next Chapter, we’ll talk about how to keep the brain healthy, banishing the myth that it can potentially “disintegrate” with age