27/03/2026
An important element is missing, that is Orthostatic hypotension.
As mentioned in the stories, non-cardiac syncope is divided into reflex-mediated and orthostatic syncope. In this third part, the focus will be on the latter, as in the article it has a separate section dedicated to its treatment. Moreover, it is (in this case) the missing piece when discussing of syncope.
1) A summary chart classifying TLOC. Highlighted in red is the part regarding syncope and this post's topic.
2) The FIVE types of orthostatic hypotension, identified by ESC guidelines. With the term "orthostatic hypotension" (OH) we can link to orthostatic syncope because drastic, abnormal drops in blood pressure can cause syncope. The term "orthostatic syncope" refers to TLOC resulting from postural decrease in BP. Orthostatic syncope can occur with or without symptoms (e.g. dizziness, fatigue, palpitations, sweating, visual and auditory disturbances, neck pain). Generally speaking, drops in blood pressure can be caused by volume depletion (e.g. vomiting, diarrhea, hemorrhage), peripheral venous pooling (e.g. prolonged bed rest), etc...
3) Diagnostic approach, and treatment.
4) "Syncope unit" - the idea of the research team of creating a multidisciplinary collaboration of specialists (cardiologists, neurologists, geriatricians - for the management of syncope into older adults -, and psychologists). Their role.
Source: Martone, A.M., Parrini, I., Ciciarello, F., Galluzzo, V., Cacciatore, S., Massaro, C., Giordano, R., Giani, T., Landi, G., Gulizia, M.M., Colivicchi, F., Gabrielli, D., Oliva, F. and Zuccalà, G.; 2024. Recent advances and future directions in syncope management: a comprehensive narrative review. Journal of clinical medicine