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Scientists have created a hydrogel that strengthens bones in weeks. Bone density increased by 5X in a lab.

A groundbreaking injectable hydrogel may soon offer a faster, more effective treatment for osteoporosis, a condition that weakens bones and increases fracture risk.

Developed by researchers at EPFL in Switzerland and startup Flowbone, this new hydrogel, made from hyaluronic acid and hydroxyapatite nanoparticles, mimics bone’s natural minerals and strengthens fragile areas. In lab tests on rats, the treatment increased bone density by up to three times within weeks. When combined with the osteoporosis drug Zoledronate, bone density at the injection site increased nearly fivefold, potentially reducing the risk of fractures far more quickly than current medications.

While the hydrogel is not a permanent fix, researchers believe it could revolutionize osteoporosis management by complementing existing drug therapies and speeding up recovery. Given that osteoporosis affects millions worldwide—especially postmenopausal women—this breakthrough could significantly lower the risk of life-threatening fractures. The team now aims to secure regulatory approval and begin clinical trials, bringing this promising technology one step closer to real-world use. If successful, it could redefine how osteoporosis is treated, offering patients faster relief and stronger bones.

Learn more: https://www.sciencedirect.com/science/article/pii/S8756328224003624?via%3Dihub