Translational Cancer Research Lab-Dr Dhruv Kumar's Lab

10/03/2026

Recent Book Chapter: Gaur, G. & Kumar, D. et al. (2026). Nanotechnology in Cancer Pharmacology: Innovations in Drug Delivery and Therapeutic Strategies. In: Emerging Trends in Cancer Pharmacology: From Molecular Targets to Personalized Medicine. Elsevier (Academic Press).

14/02/2026

Happy to share our recent review article titled “Genomic alterations and their correlation with metabolic-related genes in lung cancer” published in Clinical and Translational Oncology.
Congratulations to Gauri and the team for this excellent work! 👏
🔗 https://link.springer.com/article/10.1007/s12094-026-04229-4

Non-small cell lung cancer (NSCLC) remains the leading cause of cancer-related mortality worldwide, with 5-year survival rates below 21% primarily due to therapeutic resistance and metastatic progression. Genomic alterations in KRAS, EGFR, TP53, and MYC drive metabolic reprogramming that sustains tu...

08/02/2025

On February 4th, we observe World Cancer Day, emphasizing the importance of cancer awareness, prevention, and early detection. Raising awareness plays a crucial role in preventing cancer by enabling early diagnosis and informed decision-making. This video highlights how cancer awareness can empower individuals to take proactive steps toward prevention through early detection and knowledge sharing. Let’s join hands in spreading awareness and making a difference!

World Cancer Day, observed on February 4 every year, is a global initiative led by the Union for International Cancer Control (UICC) to raise awareness about...

05/02/2025

🎉 Congratulations to Sheeri for publishing a review article on lung cancer, "Molecular Mechanism of Genetic, Epigenetic, and Metabolic Alteration in Lung Cancer," in Medical Oncology journal! 🏆 This insightful work sheds light on the complex molecular mechanisms driving lung cancer progression. 👏🔬

Read the full article: https://link.springer.com/article/10.1007/s12032-025-02608-5

Lung cancer, a leading cause of cancer-related deaths worldwide, is primarily linked to smoking, to***co use, air pollution, and exposure to hazardous chemicals. Genetic alterations, particularly in oncogenes like RAS, EGFR, MYC, BRAF, HER, and P13K, can lead to metabolic changes in cancer cells. Th...

10/11/2024

Recent Publication:
Raj Divakar, Arun Kumar, Dhruv Kumar, Krishna Kant, and Ashish Mathur. 2024. "Gold–Graphene Quantum Dot Hybrid Nanoparticle for Smart Diagnostics of Prostate Cancer" Biosensors 14, no. 11: 534. https://doi.org/10.3390/bios14110534
Impact Factor 2023: 4.9 -- Q1 in "Chemistry, Analytical", "Instruments & Instrumentation" category

Prostate cancer is one of the most prevalent cancers afflicting men worldwide, often detected at advanced stages, leading to increased mortality rates. Addressing this challenge, we present an innovative approach employing electrochemical biosensing for early-stage prostate cancer detection. This st...

01/11/2024

Happy to share our latest publication titled, "Unveiling the Effect of Inflammatory Cytokines TNF-α, IL-6, and IL-1β in Breast Cancer Prevalence and Progression" by Priya, P.; Kumar, A.; Ghosh, A. K.; Chauhan, R.; and Kumar, D., published in Chemical Biology Letters (2024, Vol. 12, Issue 1, p. 1254). This study investigates the pivotal roles of inflammatory cytokines TNF-α, IL-6, and IL-1β in the prevalence and progression of breast cancer, offering valuable insights into the inflammatory pathways influencing tumor dynamics.

Chemical Biology Letters : a lead journal for high impact contents for medicinal chemistry, medical biochemistry, drug discovery, diagnosis and drug development

25/10/2024

Enjoy reading my blog, "Cancer: The Best Prevention is Screening and Early Detection," to learn how regular health check-ups can help prevent cancer. It’s filled with easy tips and useful information to keep you and your family healthy. A quick read that could make a big difference!
https://www.upes.ac.in/blog/health-sciences-technolog/cancer-the-best-prevention-is-screening-and-early-detection

Early cancer detection can significantly improve survival rates, reduce the need for aggressive treatments, and enhance the quality of life for patients.

13/10/2024

Recent publication from our lab:

Title: Machine Learning Techniques for Prediction of Hypertension
Authors: Priya, P. Chaudhary, K. Bhatia, Dhruv Kumar
Book: Artificial Intelligence in Healthcare
Year of Publication: 2024
Imprint: CRC Press
eBook ISBN: 9781003522096

This work explores how machine learning techniques can be applied to predict hypertension, contributing to advancements in AI for healthcare.

Hypertension, or high blood pressure, is a significant health condition affecting many people worldwide. Traditional diagnosis methods often rely on manual

06/10/2024

Publication Update:
Excited to share the publication of the book chapter titled "Treatment of Heavy Metal Induced Neurotoxicity via Advanced Drug Delivery Systems" Arun Kumar, Srivastava Abhinav, Mahesh Rachamalla, Mohammad Ali, Sneha Navin, Dhruv Kumar, and Ashok Kumar Ghosh. This chapter is part of the book "Novel Drug Delivery Systems in the Management of CNS Disorders" published by Academic Press, 393-407. ISBN: 9780443134746
https://www.sciencedirect.com/science/article/abs/pii/B9780443134746000251

05/10/2024

Received collaborative (Dr Rohit from HNBGU, Srinagar) research project from the Government of Uttarakhand (UCOST) to work on "Anti-cancer effect of air potato".

✨Heartiest congratulations to Dr Dhruv Kumar from UPES and Dr. Rohit Mahar from HNBGU for receiving a collaborative research grant from UCOST. 💐 🔬Their…

03/10/2024

October is globally recognized as Breast Cancer Awareness Month, dedicated to raising awareness about the impact of breast cancer. It serves as a reminder of the importance of early detection, support for those affected, and the ongoing need for research to improve treatments. I am sharing some important information related to breast cancer in the hope that it helps readers understand the breast cancer better and contributes to spreading awareness.

अक्टूबर को विश्व स्तर पर स्तन कैंसर जागरूकता माह के रूप में मान्यता प्राप्त है, जो स्तन कैंसर के प्रभाव के बारे में जागरूकता बढ़ाने के लिए समर्पित है। यह शीघ्र पता लगाने के महत्व, प्रभावित लोगों के लिए सहायता और उपचार में सुधार के लिए अनुसंधान की चल रही आवश्यकता की याद दिलाता है। मैं स्तन कैंसर से संबंधित कुछ महत्वपूर्ण जानकारी इस उम्मीद में साझा कर रहा हूं कि इससे पाठकों को स्तन कैंसर को बेहतर ढंग से समझने में मदद मिलेगी और जागरूकता फैलाने में योगदान मिलेगा।