Department of Toxicology, Hamdard University, New Delhi

jor funding agencies have provided financial support to its research activities and publication record of the Department is very impressive. Teachers of the Department serve on national and international committee and are also on the Editorial Board of the reputed journals in the field of toxicology. It is the only department, which has been recognised as SAP/DSA of level-II of the UGC. It has also been supported by the FIST of DST. This department proposes to upgrade its laboratories to GLP level. GLP is the pre-requisite in quality data in toxicology to meet the international regulatory requirements. This department will establish GLP laboratory and will impart training in GLP concepts to the students and faculty members of Jamia Hamdard and other universities. Basic cell culture facility has been developed in the department with support from UGC and University funds. This facility will be used for research related to cytotoxicity, genotoxicity, cancer chemoprevention, neurotoxicity, immunotoxicity and ecotoxicity. The department of Medical Elementology and Toxicology is running PG course leading to M.Sc. degree in Toxicology. Ph.D. degree in Toxicology is being awarded in different fields of toxicology. The department’s main target is to provide international quality education in Toxicology at post graduate and doctorate levels and to particularly promote study and research of herbal drugs/natural products against various environmental toxins and to evaluate the role of trace elements in health and diseases and to train our students for placement at National and International levels. The major areas of research include the role of pollutant/toxicant in biological systems, toxic manifestations and abnormalities caused by the excessive exposure to or the deficiency of such exposure. Mechanistic aspects of chemical carcinogenesis, oxidative stress, and chemo prevention aspects of disease control using herbal preparations. The department has programmes on Neuro-behavioural Toxicology, Clinical Toxicology, Biochemical Toxicology, Molecular Carcinogenesis and Cancer chemoprevention. Department has standardized techniques of in vitro (Ames test) and in vivo assessment of mutagenicity (genotoxicity). These techniques are used for evaluation of mutagenic hazard associated with drugs and chemicals. Evaluation of drugs for mutagenicity is pre-requisite for new drug development. We can cater to pharmaceutical industry in this direction. Our laboratories have enough potential to develop standardization of Unani drugs made to upgrade the Department in terms of space, equipment and manpower and get recognition from various government agencies including DBT, CSIR, ICMR, AYUSH, UGC and MoEF in terms of funded projects. RESEARCH AREAS
•Chemoprevention of carcinogenesis by herbal products and unani medicines and their standardization.
•Targeting the molecular mechanism and elucidation of their plausible role in induction of carcinogenesis in prostate, liver, kidney and skin at preclinical stage.
•Role of herbal products in amelioration of Parkinson, Alzheimer and Ischemia in rodent-model.
•Screening of natural products for their efficacy in animal model of human rheumatoid arthritis and multiple sclerosis.
•Role of venom peptide as anti-proliferative agents in cancer cell lines.
•Cellular and molecular mechanisms of nanoparticle-induced neuro toxicity.
•Role of mitochondrial permeability transition pore in neuroprotection.
•Molecular mechanism of pesticide induced toxicity.
•Immunotoxicology
•Ecotoxicology
•Environmental and health effects of endocrine disruptive chemicals.