Advanced Research Centre, USTM

12/06/2024

Protein Engineering Powers the Future of Nanobodies

Nanobodies, nature's tiny titans in the fight against disease, are poised for even greater impact thanks to the power of protein engineering. These single-domain antibodies, derived from camels and llamas, boast unique advantages over traditional antibodies: they're smaller, more stable, and can access tight spaces within cells. But protein engineering is unlocking their full potential.
Protein engineering allows scientists to tinker with the building blocks of nanobodies, fine-tuning their properties for specific applications. This opens doors for a future filled with possibilities:
• Enhanced Therapeutics: Imagine nanobodies precisely targeting cancer cells or neutralizing viruses with unmatched efficiency. Protein engineering can optimize binding affinity and functionality, leading to more potent treatments.
• Advanced Diagnostics: Nanobodies can be engineered to detect biomarkers for diseases at their earliest stages. Engineering can improve their sensitivity and specificity, making diagnostics faster and more accurate.
• Delivery Revolution: Protein engineering can equip nanobodies with the ability to deliver drugs directly to diseased cells or tissues. This targeted approach could minimize side effects and revolutionize drug delivery.
The latest research published in Nature Communications showcases this exciting future. Scientists used a cell-free platform to rapidly generate SARS-CoV-2 neutralizing nanobodies. This approach highlights the potential for rapid response to emerging pathogens.
Nanobodies, empowered by protein engineering, are poised to transform medicine. Their small size, stability, and now, their engineered potential, promise a future filled with more effective disease diagnosis, treatment, and prevention.

10/06/2024

Drug-resistant infections more likely to strike women, says WHO:

More countries must recognize how gender affects exposure to pathogens, finds a review by the World Health Organization.

Women might be more likely to develop drug-resistant infections than men — an under-recognized aspect of the growing threat of antimicrobial resistance, according to a global review led by the World Health Organization (WHO). The report finds that more than 70% of countries do not recognize gender inequalities in national plans to tackle drug-resistant infections.
And last month, the WHO added four pathogens to its list of the drug-resistant bacteria it considers to be most dangerous to humans. The list, first published in 2017, helps nations to shape their action plans against antimicrobial resistance (AMR), which is caused by the overuse and misuse of antibiotics that leads to bacteria becoming resistant to the medications through mutations in their DNA.
The changes to the list were based on how commonly the bacteria cause infections, their deadliness and how easily infections can be prevented through measures such as hand washing, quarantine and vaccination. The WHO added three streptococcal bacteria — which cause conditions including a type of pneumonia and an influenza-like infection that can be fatal in extreme cases — and a highly resistant variety of tuberculosis (see ‘Dangerous drug resistance’). The streptococci are linked to a high burden of disease, especially in poor countries, and the tuberculosis strain is difficult to detect and very expensive to treat.

08/06/2024

Congratulations to our more than 40 students from Vision 50 Academy of USTM for their outstanding performance in NEET-2024! Your hard work, dedication, and perseverance have paid off, and we couldn't be prouder of each of you.

Your success is a testament to the power of determination and the support of the incredible faculty and staff at Vision 50 Academy. Here's to your bright future in the medical field!

Keep reaching for the stars! 🌟

01/01/2024

Happy New Year 2024 from Advanced Research Centre !🎊🎉Wishing everyone a joyful, bright, healthy,prosperous and happiest new year ahead.!!

21/11/2023

18/11/2023

We are delighted to share that we hosted a group of students and faculty members from the Department of Biotechnology, Dimoria College, Kamrup,on 17th November,2023.We thank them for their visit and hope to see them again soon.

16/11/2023

🌿 Explore the world of Ayurveda at IA Ayurvedic Medical College, USTM! 🌿

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Accredited curriculum
Practical learning opportunities
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07/10/2023

Concluding a productive and successful week of hands on training.Taking place from October 3rd to October 6th, the Valedictory session of our GCMS and AAS training program, meticulously organized by the Advanced Research Centre, USTM, has proven to be an immensely enriching educational endeavor. We were delighted to host a cohort of 40 participants hailing from distinguished institution namely Tezpur University, Assam University, Bodoland University, Nagaland University, Assam Don Bosco University, as well as participants from the University of Science and Technology Meghalaya.

28/09/2023

Congratulations to the entire USTM fraternity!

08/09/2023

𝘈𝘥𝘷𝘢𝘯𝘤𝘦𝘥 𝘙𝘦𝘴𝘦𝘢𝘳𝘤𝘩 𝘊𝘦𝘯𝘵𝘳𝘦, 𝘜𝘯𝘪𝘷𝘦𝘳𝘴𝘪𝘵𝘺 𝘰𝘧 𝘚𝘤𝘪𝘦𝘯𝘤𝘦 𝘢𝘯𝘥 𝘛𝘦𝘤𝘩𝘯𝘰𝘭𝘰𝘨𝘺 𝘔𝘦𝘨𝘩𝘢𝘭𝘢𝘺𝘢 𝘪𝘴 𝘰𝘳𝘨𝘢𝘯𝘪𝘴𝘪𝘯𝘨 𝘢 𝘛𝘳𝘢𝘪𝘯𝘪𝘯𝘨 𝘗𝘳𝘰𝘨𝘳𝘢𝘮 𝘰𝘯 𝘎𝘢𝘴 𝘊𝘩𝘳𝘰𝘮𝘢𝘵𝘰𝘨𝘳𝘢𝘱𝘩𝘺 𝘔𝘢𝘴𝘴 𝘚𝘱𝘦𝘤𝘵𝘳𝘰𝘮𝘦𝘵𝘳𝘺(𝘎𝘊𝘔𝘚) & 𝘈𝘵𝘰𝘮𝘪𝘤 𝘈𝘣𝘴𝘰𝘳𝘱𝘵𝘪𝘰𝘯 𝘚𝘱𝘦𝘤𝘵𝘳𝘰𝘴𝘤𝘰𝘱𝘺(𝘈𝘈𝘚). 𝘞𝘦 𝘪𝘯𝘷𝘪𝘵𝘦 𝘴𝘵𝘶𝘥𝘦𝘯𝘵𝘴, 𝘳𝘦𝘴𝘦𝘢𝘳𝘤𝘩𝘦𝘳𝘴, 𝘗𝘩𝘋 𝘴𝘤𝘩𝘰𝘭𝘢𝘳𝘴 & 𝘍𝘢𝘤𝘶𝘭𝘵𝘪𝘦𝘴 𝘵𝘰 𝘫𝘰𝘪𝘯 𝘰𝘶𝘳 𝘱𝘳𝘰𝘨𝘳𝘢𝘮 𝘢𝘯𝘥 𝘢𝘷𝘢𝘪𝘭 𝘵𝘩𝘪𝘴 𝘰𝘯𝘦 𝘰𝘧 𝘢 𝘬𝘪𝘯𝘥 𝘭𝘦𝘢𝘳𝘯𝘪𝘯𝘨 𝘰𝘱𝘱𝘰𝘳𝘵𝘶𝘯𝘪𝘵𝘺.

Advanced Research Centre, USTM

04/09/2023

A Proud Moment for India! 🇮🇳

Congratulations to ISRO and the brilliant scientists behind it for achieving another incredible milestone! 🎉

ISRO has successfully launched India's maiden solar mission, Aditya-L1, from Sriharikota today. 🛰️

Aditya-L1 is a groundbreaking space-based observatory designed to study the Sun like never before. It was launched using ISRO's reliable Polar Satellite Launch Vehicle (PSLV) at 11.50 am. 🚀

Over the next 125 days, this spacecraft will embark on a journey of approximately 1.5 million km from Earth to reach a Halo orbit around the Lagrangian point L1, which is the closest point to the Sun. ☀️

The Aditya-L1 mission holds several key objectives, including:
🌟 Understanding Coronal Heating and Solar Wind Acceleration
🌟 Studying the initiation of Coronal Mass Ejections
🌟 Monitoring near-earth space weather
🌟 Analyzing the distribution of solar wind

To accomplish these goals, the mission is equipped with seven scientific payloads. 📡

This remarkable achievement is yet another testament to India's prowess in space exploration. Let's take pride in this moment and applaud the dedication and brilliance of our scientists at ISRO! 🙌👨‍🔬👩‍🔬

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