MRM group - Supramolecular polymer lab

08/03/2026

We are happy to share another latest publication in the prestigious RSC journal "Chemical communication".
"Congratulations to Sujauddin".
This work reports a naphthalimide-based colorimetric and luminescent organic sensor was developed for the visual detection and facile quantification of trace amounts of water in organic solvents such as THF, DMSO, and deuterated NMR solvents, using a color chart and smartphone-based application.
Thanks to the University of Calcutta for infrastructural support and the Anusandhan National Research Foundation - ANRF - for funding support.

A naphthalimide-based colorimetric sensor was developed for the visual detection and facile quantification of trace water in organic solvents, deuterated NMR solvents, liquid and solid samples using a colour chart and a smartphone application.

30/01/2026

We are happy to share another latest publication in the prestigious ACS journal "Macromolecules".
"Congratulations to Arun".
This work reports a mild, open-air cascade ring-opening polymerization strategy for synthesizing functional poly(disulfide)s. An amine-activated thiolactone generates a thiolate initiator that enables room-temperature polymerization of PFP-ester-containing cyclic disulfides. Subsequent in situ postpolymerization modification allows dual chain-end and pendant functionalization via transesterification and amidation. This versatile platform provides access to multifunctional dynamic covalent poly(disulfide)s with minimal synthetic steps.

Dynamic covalent poly(disulfide)s are regarded as sustainable intelligent materials for the future because of their dynamicity and recyclability. Consequently, establishing a comprehensive process for the synthesis of poly(disulfide)s with varied structures and functionalities is highly valuable. Th...

24/12/2025

Congratulations, Soumya Kolay for this wonderful work. We thank Prof. Biplab Giri (Gour Banga University ), Prof. Subhas Haldar (Bose Institute) and Prof Arunima Sengupta (Jadavpur University) for the collaboration. We also thank Dey Sananda, Tanushree and Madhuchhanda for Biological work. In this Biomacromolecules paper, we have demonstrated a polyurethane nanonetwork-based robust platform for cocktail chemotherapy. Biological evaluation confirmed a potent cytotoxicity in triple negative breast cancer cells. To see more details, please follow the link. We thank Anusandhan National Research Foundation - ANRF for funding and University of Calcutta for infrastructural support.

We formulated a nanonetwork of an amphiphilic polyurethane integrated with a tertiary amine group on the backbone and a pyridyl disulfide group as a pendant. The disulfide linkages within the nanonetwork undergo reductive cleavage in the intracellular redox environment of cancer cells, enabling sust...

12/11/2025

Congratulations @ Soumya Kolay, , and for ACS Applied Nano Materials paper, which demonstrates polymer prodrug for targeted cancer therapy. Thanks to Prof. Biplab Giri and Dr. Subhash Haldar for Biological collaboration. Thanks to the University of Calcutta for infrastructural support and the Anusandhan National Research Foundation (ANRF) for funding support.

Cancer remains one of the foremost causes of mortality worldwide. Among the different cancer therapies, chemotherapy is one of the widely used treatments, but its clinical efficacy is often compromised by serious side effects arising from the off-target release of cytotoxic drugs. Here, we reported....

05/09/2025

🎉 "A day full of gratitude, laughter, and learning — Teacher’s Day made special by my amazing students!" 🙌✨

06/07/2025

"Congratulations Asmita, Sayani and Shuvajyoti" on securing a Ph.D. position at University of illinois, Chicago : Asmita
University of Massachusetts, Amherst : Sayani
University of Alberta, Canada : Shuvajyoti.
This is a remarkable achievement and well deserved recognition of your hard work, dedication and academic excellence. It was very nice to supervise you all in your project period.
Wishing you all continued success, good health and inspiring academic journey ahead.

04/04/2025

Our paper in "Journal of Macromolecular Science, Part A" entitled " Amphiphilic Poly(disulfide)s by a Three Component Cascade Reactions: A Therapeutic Architecture for Redox Responsive Intracellular Drug Delivery" appeared as a front cover page.
full paper : doi.org/10.1080/10601325.2025.2454283

14/03/2025

Sayani received the best poster presentation award in one day National Conference on "MATERIALS REVOLUTION: PIONEERING ADVANCES IN SCIENCE AND TECHNOLOGY", organized by Department of Chemistry, Amity Institute of Applied Sciences, Amity University Kolkata in collaboration with Royal Society of Chemistry on 27th February 2025.
Congratulations Sayani…

15/02/2025

We are very happy to share our another latest publication in prestigious journal " Journal of Macromolecular Science, Part A".
"Congratulations Arun".
Here, we developed an amine activated cascade initiation of thiolate-induced ring opening polymerization (ROP) of the 1,2-dithiolane ring to synthesize functional poly(disulfide)s at room temperature and under an open-air condition. The poly(disulfide) (PDS) formed stable 100 nm nanocarriers in aqueous media via an entropically driven process, with low CAC and high encapsulation stability. It showed complete redox-triggered (GSH) degradation and ~84% controlled guest release. MTT assays confirmed excellent biocompatibility (>90% HeLa cell viability), while PDS@DOX induced >70% cell death in 24 hours. Fluorescence microscopy revealed time-dependent cellular uptake and doxorubicin diffusion to the nucleus, leading to cancer cell death.

We reported a new cascade type of synthetic methodology for poly(disulfide)s (PDS) from lipoic acid-based monomer. The primary amine-based activator and thiolactone initiator was used for the synth...

11/02/2025

Soumya received the best oral presentation award in a conference on 6th Regional Science and Technology Congress 2024–25, Region 6, organized by Calcutta University.
Congratulations to Soumya...

11/02/2025

Congratulations, Sayani for receiving the Best Poster Award in the international Conference on Chemistry for Human Development (ICCHD-2025), organized by the Dept. of Chemistry, University of Calcutta.