MRCP Preps with Dr. Faiz

MRCP Preps with Dr. Faiz This platform is to help people on PLAB journey, MRCP Pathway, GMC registration sharing notes and tactics to ace this exam.

25/08/2026

● Coeliac Disease : High-Yield MRCP Points

• Classic presentation: Chronic diarrhoea, bloating, weight loss and steatorrhoea due to small-bowel malabsorption.

• Iron-deficiency anaemia is a key clue: Especially unexplained or refractory iron deficiency despite adequate iron replacement.

• Associated deficiencies: Folate, vitamin B12, calcium and vitamin D deficiencies can occur, causing neuropathy, osteopenia/osteoporosis and fatigue.
• Diagnosis: First-line test is IgA anti-tTG antibody + total IgA. If IgA deficient, use IgG-based serology.

• Important associations: Dermatitis herpetiformis, type 1 diabetes, autoimmune thyroid disease and Down syndrome. Diagnosis is confirmed with duodenal biopsy showing villous atrophy and crypt hyperplasia in appropriate cases.

23/08/2026

● MRCP(UK) Part 1 – 2027 Exam Dates

1) January 2027 Diet:
• Exam: 20 January 2027
• Applications: 27 October – 3 November 2026

2) May 2027 Diet:
• Exam: 26 May 2027
• Applications: 9 – 16 March 2027

3) September 2027 Diet:
• Exam: 29 September 2027
• Applications: 13 – 20 July 2027

Fee 696£

Lung volume and Capacity
22/08/2026

Lung volume and Capacity

22/08/2026

● Hepatorenal Syndrome

• HRS is a functional renal failure in advanced cirrhosis, caused by severe splanchnic vasodilatation and renal vasoconstriction.

•Common precipitants: SBP, sepsis, GI bleeding, excessive diuresis and large-volume paracentesis without adequate albumin.

• Diagnosis is by exclusion: AKI in cirrhosis with no significant proteinuria/haematuria, bland urine sediment and no evidence of structural kidney disease.

• HRS-AKI treatment: albumin + vasoconstrictor, preferably terlipressin where appropriate. ⭐⭐⭐

• Liver transplantation is the definitive treatment; renal replacement therapy may be used as a bridge to transplantation

Red eye differentials
17/08/2026

Red eye differentials

15/08/2026

● Imp Point for MRCP mcqs

Forced vital capacity FVC is the measure of the force, volume and speed with which air can be maximally expelled from the lungs

FVC is the best way to monitor respiratory function in any neurological disorders that can affect the respiratory muscles
Neurological conditions like Gullain Barre syndrome and Myasthenia Gravis
Normal FVC value is 45 - 75 ml/kg

ITU admission is recommended when FVC is less than 20ml/Kg and intubation is recommended when FVC is less than 15ml/Kg

10/08/2026

Acute Exacerbation of COPD — 5 High-Yield MRCP Points

1) Controlled oxygen: target SpO₂ 88–92%
Give oxygen cautiously, particularly in patients at risk of hypercapnic respiratory failure. Check an ABG to assess CO₂ retention and pH.

2) Bronchodilators are first-line
Use nebulised salbutamol ± ipratropium. If hypercapnia is a concern, nebulisers should preferably be air-driven rather than oxygen-driven.

3) Give systemic corticosteroids
A short course of oral prednisolone reduces recovery time, treatment failure and relapse. IV steroids are generally reserved when oral treatment is not possible.

4) Antibiotics are not required in every exacerbation
Consider antibiotics when there is increased sputum purulence, particularly when accompanied by increased sputum volume or worsening dyspnoea, or when the patient is severely unwell.

5) NIV for persistent hypercapnic acidosis
If optimal medical treatment fails and ABG shows pH

Red Eye differentials for MRCP Part 1
09/07/2026

Red Eye differentials for MRCP Part 1

MRCP Preps with Dr. FaizTYPE 2 DIABETES MELLITUS MANAGEMENT (NICE/NHS 2026)1. Lifestyle Measures (For All Patients)Struc...
02/07/2026

MRCP Preps with Dr. Faiz
TYPE 2 DIABETES MELLITUS MANAGEMENT (NICE/NHS 2026)
1. Lifestyle Measures (For All Patients)
Structured diabetes education
Healthy diet & weight reduction
≥150 min/week moderate exercise
Smoking cessation
Reduce alcohol intake
Manage cardiovascular risk factors
2. Individualise HbA1c Target
Usually 48 mmol/mol (6.5%)
Relax targets in frailty, older adults, or high hypoglycaemia risk
3. Initial Pharmacological Therapy
Most patients ➡️ Modified-release Metformin + SGLT2 inhibitor
If metformin contraindicated/intolerant: ➡️ SGLT2 inhibitor alone (if appropriate)
4. Treatment According to Comorbidities
❤️ ASCVD
SGLT2 inhibitor
Consider GLP-1 receptor agonist if further control required
🫀 Heart Failure
SGLT2 inhibitor preferred
🩺 Chronic Kidney Disease
SGLT2 inhibitor (if eligible)
ACE inhibitor/ARB if albuminuria
⚖️ Obesity
GLP-1 receptor agonist or tirzepatide where appropriate
5. If HbA1c Remains Above Target
Add therapy according to patient factors:
DPP-4 inhibitor
Sulfonylurea
Pioglitazone
GLP-1 receptor agonist
Basal insulin when indicated
6. Cardiovascular & Renal Protection
Blood pressure control
Statin therapy
Annual kidney assessment
Retinal screening
Foot examination
Vaccinations
7. Monitoring
HbA1c every 3–6 months
eGFR & UACR
Weight/BMI
Blood pressure
Lipid profile
Review adherence & adverse effects

Key Message (Bottom Banner)
"Treat Beyond Glucose: Prioritise Cardiovascular and Renal Protection with Individualised Patient-Centred Care."

Precaution before use of Statins One question for Your MRCP-1 exam💊 STATINS & LFT MONITORING Before starting statins, ch...
25/06/2026

Precaution before use of Statins One question for Your MRCP-1 exam
💊 STATINS & LFT MONITORING

Before starting statins, check baseline ALT (± AST) to identify pre-existing liver disease and for future comparison.

📌 Routine monitoring:
✔️ LFT at 3 months
✔️ LFT at 12 months
❗No routine monitoring afterward unless symptoms develop.

⚠️ Important:
Mild ALT/AST elevation (

Address

Slough

Website

Alerts

Be the first to know and let us send you an email when MRCP Preps with Dr. Faiz posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Shortcuts

Share

Category