M.Med.Sci in Assisted Reproduction Technology

Congratulations to Classes of 2019-20 and 2020-21 who were able to graduate in person yesterday and today. Steph and I were privileged to be part of the platform party for both ceremonies. As always, I wish all our students all the very best for their future careers and lives! Thanks for the memories, Nicky # # #

Always a wonderful occasion when we are able to take some of our ART student's work and see it published. Here is a review article on the paternal programming of offspring health written with two of our ART students from 2019-2020

Paternal programming of offspring health In recent years, a new focus of the Developmental Origins of Health and Disease hypothesis has emerged examining the potential role that paternal heal…

See the latest research article from one of our academic team into the impact of IVF on offspring health in mice.

duration of embryo culture after mouse IVF differentially affects cardiovascular and metabolic health in male offspring AbstractSTUDY QUESTION. Do the long-term health outcomes following IVF differ depending upon the duration of embryo culture before transfer?SUMMARY ANSWER. Us

World Embryologist Day!
Today was chosen because it is Louise Brown' birthday, the 1st IVF baby. Congratulations to embryologists worldwide, thank you for all your hard work in making miracles happen every day and Happy Birthday Louise :)

A very well attended webinar on Time Lapse Technology with Interesting deliberations on over a decade long experience with TL systems by a panel of international experts

Our latest work showing that first and second generation offspring cardiovascular function are impaired in response to either s***m or seminal fluid from males fed a low protein diet.
https://physoc.onlinelibrary.wiley.com/doi/abs/10.1113/JP278270

And further on, maternal preimplantation low protein diet influences offspring bone development and growth
https://www.cambridge.org/core/journals/journal-of-developmental-origins-of-health-and-disease/article/periconception-maternal-lowprotein-diet-adversely-affects-male-mouse-fetal-bone-growth-and-mineral-density-quality-in-late-gestation/CA9F36953E63320FDF76DE10145FADAD

The MMedSci ART team recently published ''Apoptosis triggers the release of microRNA miR-294 in spent culture media of blastocysts'' in the Journal of Assisted Reproduction and Genetics. Feel free to read and share here: https://rdcu.be/b4kJ5

Apoptosis triggers the release of microRNA miR-294 in spent culture media of blastocysts To study whether members of the miR-290-295 cluster in spent culture medium (SCM) of embryos are correlated with morphokinetics and apoptosis. Cryopreserved 1-cell stage mouse embryos were cultured to the blastocyst stage, development was monitored by time-lapse, 59 SCM were collected, and miR-291a....

We’re helping in the fight against COVID-19
https://www.nottingham.ac.uk/alumni/newseventsandfeatures/news/news-items/alt/we're-helping-in-the-fight-against-covid-19.aspx

We're helping in the fight against COVID-19 - The University of Nottingham

It is a difficult and challenging time, and we send our best wishes. On a bright side, we want to congratulate our colleagues and students on their recent publications:

Bovine S***m Sexing Alters S***m Morphokinetics and Subsequent Early Embryonic Development
https://www.nature.com/articles/s41598-020-63077-6

Observational retrospective study of UK national success, risks and costs for 319,105 IVF/ICSI and 30,669 IUI treatment cycles
https://bmjopen.bmj.com/content/10/3/e034566.long

Low protein diet and methyl-donor supplements modify testicular physiology in mice
https://rep.bioscientifica.com/view/journals/rep/159/5/REP-19-0435.xml

Regulatory mechanisms for natriuretic peptide signalling in sheep granulosa cells
https://jme.bioscientifica.com/view/journals/jme/64/4/JME-20-0034.xml

Maternal periconceptional and first trimester protein restriction in beef heifers: effects on placental parameters and fetal and neonatal calf development https://www.publish.csiro.au/RD/RD19017

Bovine S***m Sexing Alters S***m Morphokinetics and Subsequent Early Embryonic Development In artificial insemination the use of sex-sorted bovine s***m results in reduced conception, the causes of which are only partly understood. Therefore, we set out to investigate the effects of sexing on bovine s***m function and early embryonic development. Computer-assisted semen analysis (CASA) of...

See the latest ESHRE published paper summarising current knowledge on time-lapse technology, including limits & benefits. The paper presents how to make use of time-lapse for those who choose to do so. On our course you will learn all about the latest non-invasive techniques for embryo culture.

https://www.eshre.eu/Guidelines-and-Legal/Guidelines/TLT

TLT