MRC Centre for Global Infectious Disease Analysis

WHO Collaborating Centre for infectious disease modelling @ImperialCollege

Operating as usual

21/06/2024

NEW EPISODE ! This week, Dr Sabine van Elsland speaks with Dariya Nikitin about meningococcal vaccination to protect against Gonorrhoea.

The full text published in the Journal of infectious of Infectious Diseases on cost-effectiveness of 4CMenB Vaccination Against Gonorrhea and the importance of Dosing Schedule, Vaccine Sentiment, Targeting Strategy, and Duration of Protection can be accessed here: https://doi.org/10.1093/infdis/jiae123

07/06/2024

NEW EPISODE This week Dr Sabine L. van Elsland speaks with Jack Wardle about the use of flight passenger data in real-time modelling to inform epidemic response 👇

The full text published in the Journal of Travel Medicine International Society of Travel Medicine ISTM on temporal variations in international air travel- implications for modelling the spread of infectious diseases can be accessed here:
https://academic.oup.com/jtm/article/31/4/taae062/7649242?login=false

05/06/2024

NEW EPISODE! This week Sabine van Elsland speaks with Julia Michalow about the management of s*xually transmitted infections or STIs in sub-Saharan African countries

➡️Effective syndromic management of vaginal discharge, urethral discharge & ge***al ulcer following World Health Organization guidelines

Read more in this PLOS Medicine systematic review & meta-regression of the aetiology of vaginal discharge, urethral discharge, and ge***al ulcer in sub-Saharan Africa https://doi.org/10.1371/journal.pmed.1004385

Imperial College London National Institute for Communicable Diseases CeSHHAR Zimbabwe Harvard T.H. Chan School of Public Health Liverpool School of Tropical Medicine - LSTM

24/05/2024

NEW EPISODE of ! This week Dr Sabine van Elsland speaks with Dr Leonid Chindelevitch about the detection of antimicrobial resistance from genomic data using machine learning & artificial intelligence to inform nuanced clinical decisions for medication prescriptions.

The full paper published in Microbial Genomics on optimising machine learning prediction of minimum inhibitory concentrations in Klebsiella pneumoniae
https://doi.org/10.1099/mgen.0.001222

21/05/2024

NEW EPISODE! This week Dr Sabine L. van Elsland speaks with Dr Rob Johnson about healthy populations as a pandemic preparedness strategy in Mexico.

Did you know warning labels on products & taxes on certain foods can be an effective strategy?

Read this full simulation study from Mexico on promoting healthy populations as a pandemic preparedness strategy in Lancet Regional Health Americas
https://doi.org/10.1016/j.lana.2024.100682

21/05/2024

NEW EPISODE! This week Dr Sabine van Elsland speaks with Dr Rob Johnson about healthy populations as a pandemic preparedness strategy in Mexico.

Did you know warning labels on products & taxes on certain foods can be an effective strategy?

Read this full simulation study from Mexico on promoting healthy populations as a pandemic preparedness strategy in The Lancet Regional Health Americas
https://doi.org/10.1016/j.lana.2024.100682

03/05/2024

NEW EPISODE ! This week Dr Sabine van Elsland speaks with Dr Anne Cori about privilege in academic modelling careers 👇

➡️Did you know it takes a non-native speaker twice as long to read a scientific paper?
➡️Examples include gender, ethnicity, s*xual orientation, language and caring responsibilities

One to watch 📺!

"SIR… or MADAM? The impact of privilege on careers in epidemic"
This publication in Elsevier now available!
Discussing a move from SIR models (Susceptible-Infectious-Recovered) towards the MADAM diversity and privilege framework: Momentum, Awareness, Dissemination, Action and Mitigation 👇
https://www.sciencedirect.com/science/article/pii/S1755436524000306?dgcid=rss_sd_all

Watch the full plenary talk by as presented at here 👇
https://youtu.be/Jcr2dbiqLY4?si=awqb6MA3OtHhYG3j

Read this Imperial College London news item on this plenary talk with expert insights 👇 https://www.imperial.ac.uk/news/249996/privilege-epidemic-modelling-careers/

26/04/2024

NEW EPISODE! This week, Dr Sabine van Elsland speaks with Dr Katy Gaythorpe and Anna-Maria Hartner about the impact of disruptions to routine and campaign immunization caused by the COVID-19 pandemic.

Read the full modelling study in The Lancet Global Health on estimating the health effects of related immunisation disruptions in 112 countries during 2020–30 👇
https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(23)00603-4/fulltext

This week is World Immunization Week celebrating 50 years of the Expanded Programme on Immunization and recognizing collective efforts to save and improve countless lives from vaccine-preventable diseases and calling on countries to ramp up investments in immunization programmes to protect the next generations. Read more 👇
https://www.who.int/campaigns/world-immunization-week/2024

Episode first released on X (26-04-2024):
https://x.com/MRC_Outbreak/status/1783767894678966380

22/03/2024

What is genetic epidemiology and how does this help malaria control programmes?
In this episode of , Dr Sabine van Elslandspeaks with Dr Shazia Ruybal Pesántez about their recent paper in Trends in Parasitology on molecular markers for malaria genetic epidemiology, progress and pitfalls https://doi.org/10.1016/j.pt.2023.11.006

15/03/2024

NEW EPISODE ! This week, Dr Sabine van Elsland speaks with Dr Ilaria Dorigatti and Prof Nicholas Grassly about the MRC Centre research theme on vaccines and therapeutics 👇

Read more about this theme and our research on
➡️ Early life intestinal microbiome,
➡️ Development of new prevention tools,
➡️ Public health impact and evaluation of therapeutics and vaccines,
➡️ Interventions such as mass drug administration to improve population health

Visit our website: https://www.imperial.ac.uk/mrc-global-infectious-disease-analysis/research-themes/vaccines-and-therapeutics-/

22/02/2024

New episode !

This week Sabine L. van Elsland speaks with Rosie Maddren & Prof Sir Roy. Anderson from the London Centre for Neglected Tropical Disease Research about helminth transmission & control 👇

Read more about measuring heterogeneities in soil-transmitted helminth transmission and control in this recent paper in Trends in Parasitology: https://doi.org/10.1016/j.pt.2023.11.003

15/02/2024

NEW EPISODE ! This week Sabine van Elsland speaks with Oliver Stevens & Dr Romain Silhol about the new UNAIDS estimates of HIV among key populations 👇

➡️Did you know partners of key populations often acquire as many new HIV infections as key populations themselves?

Interested to read more about the UNAIDS estimates? Check out this recent publication in JAIDS 👉https://journals.lww.com/jaids/toc/2024/01011

The HPTN Modelling Centre is a collaborative centre that develops and uses mathematical models to support HPTN research activities and inform research directions
👉https://hptnmodelling.org/

The UNAIDS Reference Group is an international group of epidemiologists, demographers, statisticians and public health experts that work together with UNAIDS and a Secretariat at SACEMA (DSI-NRF CoE in Epidemiological Modelling and Analysis) Stellenbosch University
👉https://epidem.org/

09/02/2024

NEW EPISODE of ! In this episode of Science In Context, Dr Sabine van Elsland speaks with Dr Nora Schmit and Dr Hillary Topazian about modelling the clinical efficacy and cost effectiveness of the new malaria vaccine R21/Matrix-M.

Find out more about this mathematical modelling study in today's publication on the public health impact and cost-effectiveness of the R21/Matrix-M malaria vaccine 👇
https://doi.org/10.1016/S1473-3099(23)00816-2

Episode first released on X / https://x.com/MRC_Outbreak (09-02-2024):
https://x.com/MRC_Outbreak/status/1755911759196500148?s=20

07/02/2024

Have you always wanted to learn about mathematical modelling, epidemiology & control of infectious disease? Check out our two week short-course at Imperial College London!

📅 8-20 September 2024
💡 Free math & Excel refresher
💰 Scholarships available
✏ Find out more & apply: https://infectiousdiseasemodels.org

Presenters include:
Dr Anne Cori, Prof Azra Ghani, Prof Neil Ferguson, Prof Thomas Churcher, Prof Timothy Hallett, Prof María-Gloria Basáñez, Prof Nicholas Grassly, Prof Katharina Hauck, Prof Peter J White, Dr Clare McCormack, Dr Lilith Whittles

26/01/2024

New episode of ! This week speaks with Dr Nicholas Croucher about the immune response of children to the pneumococcus bacteria 👇

Find out more about this research in the recent publication on genomic and panproteomic analysis of the development of infant immune responses to antigenically-diverse pneumococci 👇
https://doi.org/10.1038/s41467-023-44584-2

08/12/2023

NEW EPISODE ! This week Sabine van Elsland speaks with Anna Carnegie and Katharine Sherratt of the London School of Hygiene & Tropical Medicine reflecting on experiences from members of the UK infectious disease modelling community during the pandemic.

Find out more about this workshop in the report: https://www.biorxiv.org/content/10.1101/2023.06.12.544667v1

29/11/2023

New episode of Science In Context! This week Dr Sabine van Elsland speaks with Gina Cuomo-Dannenburg about Marburg Virus Disease and the first publication in a series of systematic reviews on outbreaks, mathematical models and disease parameters of nine infectious diseases prioritized on the World Health Organization blueprint list.

Hot off the press in The Lancet Infectious Diseases this systematic review of Marburg virus disease outbreaks, mathematical models, and disease parameters: https://authors.elsevier.com/a/1iAGX5E-UocjBb

Episode 83. first published on X (29-11-2023):

26/10/2023

NEW EPISODE of this week Sabine van Elsland speaks with James Stannah about a collaborative study with PAC-CI in Cote d'Ivoire on men who have s*x with men, stigma & structural barriers to HIV prevention & treatment and the UNAIDS 95-95-95 targets.

Find out more about trends in HIV testing, the treatment cascade, and HIV incidence among men who have s*x with men in Africa in this systematic review & meta-analysis in The Lancet HIV 👇
https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(23)00111-X/fulltext

Programme PACCI, Site ANRS de Côte d'Ivoire Imperial College London McGill University Institut national de santé publique du Québec (INSPQ)

Episode first released on X (26-10-2023):
https://x.com/MRC_Outbreak/status/1717586620340191422?s=20

26/10/2023

OPPORTUNITY! Applications now open for our 4 year PhD programme in epidemiology, evolution & control of infectious diseases:

💼 1+3 MRes and PhD
📅 Application deadline Monday 8 January 2024
✏ Find out more and apply: https://lnkd.in/eEyDxj9R

All applicants are strongly recommended to also apply for the MRC doctoral training programme for Interdisciplinary Science in Health (deadline 16 November 2023, more information https://lnkd.in/eztg_rGs)

Imperial College London

03/10/2023

NEW EPISODE ! This week Dr Sabine van Elsland speaks with Prof Azra Ghani, director of the MRC Centre for Global Infectious Disease Analysis about securing funding for the next three years, the newly established translational hub and her vision for the future of the MRC Centre.

Interested to read more? Professor Azra Ghani takes the reins of renewed MRC Centre:
https://www.imperial.ac.uk/news/247457/professor-azra-ghani-takes-reins-renewed/

MRC Centre for Global Infectious Disease Analysis Website:
https://www.imperial.ac.uk/mrc-global-infectious-disease-analysis
X: : https://twitter.com/MRC_Outbreak

Episode first released on X (29-09-2023):
https://x.com/MRC_Outbreak/status/1707668989751566476?s=20

Imperial College London

20/09/2023

New episode now out!Dr Sabine van Elsland speaks with Prof Samir Bhatt about mathematical modelling for infectious diseases highlighting branching theory 👇

Interested to read more?
MJ Penn et al. Intrinsic randomness in epidemic modelling beyond statistical uncertainty. Nature Communications Physics 2023. DOI: https://doi.org/10.1038/s42005-023-01265-2

and

Pakkanen et al. Unifying incidence and prevalence under a time-varying general branching process. Journal of Mathematical Biology 2023. DOI: https://doi.org/10.1007/s00285-023-01958-w

Episode first released on X (20-09-2023):
https://x.com/MRC_Outbreak/status/1704496680370839661?s=20

14/09/2023

New episode 👇

This week Sabine van Elsland speaks with Prof Lucie Cluver and Dr Jeff Imai-Eaton urging the reauthorisation of in their letter in The Lancet with colleagues Lorraine Sherr, Mary Mahy and Seth Flaxman

Did you know $7 billion a year of funding

➡️Saved 25 million lives
➡️Ensures treatment for 20 million people
➡️Has reduced number of children born with HIV by 80%

Read the letter in The Lancet producing the science to support the need to reauthorise PEPFAR to prevent death, orphanhood, & suffering for millions of children 👇

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(23)01723-3/fulltext #%20

Episode first released on X (14-09-2023):
https://x.com/MRC_Outbreak/status/1702262390648156516?s=20

08/09/2023

NEW EPISODE ! This week Dr Sabine van Elsland speaks with Dr Joe Challenger about the impact of bacteria on the incidence of 👇

Interested to find out more? This study was published in Science focussed on Delftia tsuruhatensis TC1 symbiont suppresses malaria transmission by anopheline mosquitoes: https://www.science.org/doi/10.1126/science.adf8141

Imperial College London GSK Johns Hopkins Bloomberg School of Public Health

04/08/2023

New episode ! This week Sabine van Elsland speaks with Rosie Maddren about challenges of fieldwork for + scientists and the importance of allies - one to watch!

Did you know that + scientists on travel for fieldwork:
➡️61% felt uncomfortable & unsafe when travelling
➡️92% consider travel important for career
➡️38% chose not to travel because they felt unsafe

📖Read more in this paper by Dr Christina Atchison in Nature Human Behaviour:
https://www.nature.com/articles/s41562-021-01205-6

The Imperial College London LGBTQ+ International Support Group was set up to help improve the overall experience for + staff & student travellers.
📖 Read more about this initiative in this blog: https://blogs.imperial.ac.uk/imperial-medicine/2023/06/21/lgbtqia-international-support-group/

Imperial College London Medical Research Council

27/07/2023

In this episode of , Dr Sabine L. van Elsland speaks with Dr Anne Cori about the pathogen epidemiology review group, their R Package EpiReview and the catalogue for mathematical modelling parameters which aims to facilitate rapid response to potential outbreaks of nine WHO priority pathogens

Find out more about the R Package and access the latest data, figures and tables from our Pathogen Epidemiology Review Group on our GitHub Page:
🌐 https://github.com/mrc-ide/epireview

Details of the systematic review methodology are available on PROSPERO . The nine World Health Organization priority pathogen viruses that eventually will be included are Marburg, Nairo, Ebola, Henipa, Lassa, MERS, Rift Valley fever, SARS-CoV-1 & Zika. The PROSPERO Record can be accessed here:
🌐 https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=393345

The first pre-print (not yet peer reviewed) is available on medRxiv on Marburg Virus Disease:
🌐 https://www.medrxiv.org/content/10.1101/2023.07.10.23292424v1

Interested in the World Health Organization Collaboratory Epiparameter Community anne cori speaks about in this episode - visit their GitHub
🌐 https://worldhealthorganization.github.io/collaboratory-epiparameter-community

Imperial College London

21/07/2023

NEW EPISODE ! As Science Advances publishes on Aspergillus fumigatus today, Dr Sabine van Elsland speaks with Dr Jennifer Shelton to find out more about this study 👇

Interested? Read the full paper entitled "Citizen science reveals landscape-scale exposures to multiazole-resistant Aspergillus fumigatus bioaerosols" here👇
https://doi.org/10.1126/sciadv.adh8839

Read more about this topic with insights from Jennifer Shelton and Matthew Fisher in this news item 👇
https://www.imperial.ac.uk/news/246116/citizen-science-shows-widespread-exposure-drugresistant/

Imperial College London UK Centre for Ecology & Hydrology

18/07/2023

New episode of out now! Today, Dr Sabine van Elsland speaks with Dr Pablo Perez and Dr Edward Knock about their publication in Nature Communications where they present the epidemiological drivers of transmissibility and severity of SARS-CoV-2 in England.

Interested to read more? The Nature Communications paper is available here: https://www.nature.com/articles/s41467-023-39661-5

Episode first released on Twitter (18-07-2023):
https://twitter.com/MRC_Outbreak/status/1681291628693127171?s=20

13/07/2023

Pre-print out now on medRxiv! (not yet peer reviewed)

Our pathogen epidemiology review group is building a catalogue of outbreaks, mathematical models, and disease parameters for 9 World Health Organization priority pathogens.

First up is Marburg Virus Disease 👇
https://www.medrxiv.org/content/10.1101/2023.07.10.23292424v1

Details of the systematic review methodology are available on 👇
https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=393345

Following this Marburg review, additional pathogens will be added to the catalogue including Nairo, Ebola, Henipa, Lassa, MERS, Rift Valley fever, SARS-CoV-1 & Zika

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Videos (show all)

Ep98. Science in Context - Dariya Nikitin
Ep 97. Science in Context - Flight data with Jack Wardle
Ep 96. Science in Context - STI syndromic management with Julia Michalow
Ep 95. Science in Context - AMR with Dr Leonid Chindelevitch
Ep 94. Science in Context Dr Rob Johnson
NEW EPISODE! This week Dr Sabine van Elsland speaks with Dr Rob Johnson about healthy populations as a pandemic prepared...
E93. Science in Context Dr Anne Cori
NEW EPISODE! This week, Dr Sabine van Elsland speaks with Dr Katy Gaythorpe and Anna-Maria Hartner about the impact of d...
What is genetic epidemiology and how does this help malaria control programmes?In this episode of #ScienceInContext, Dr ...
NEW EPISODE #ScienceInContext! This week, Dr Sabine van Elsland speaks with Dr Ilaria Dorigatti and Prof Nicholas Grassl...
New episode #ScienceInContext!This week Sabine L. van Elsland speaks with Rosie Maddren & Prof Sir Roy. Anderson from th...
NEW EPISODE #ScienceInContext! This week Sabine van Elsland speaks with Oliver Stevens & Dr Romain Silhol about the new ...

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