Formulation and Industrial Pharmacy

Publication published!

Molecular Pharmaceutics https://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.9b01263

Surface Stabilization and Dissolution Rate Improvement of Amorphous Compacts with Thin Polymer Coatings: Can We Have It All?

Dunja Novakovic, Leena Peltonen, Antti Isomäki, Sara J. Fraser-Miller, Line Hagner Nielsen, Timo Laaksonen and Clare J. Strachan

Congratulations!

A paper accepted from Industrial Pharmacy team: Industrial PhD student Krista Ojala (Orion) who has done a long career in industry. Her thesis topic is dissolution in different phases of pharmaceutical development.

"Prediction of drug dissolution from Toremifene 80 mg tablets using NIR spectroscopy"
(International Journal of Pharmaceutics, Available online 16 January 2020, 119028)

Krista Ojala, Mika Myrskyranta, Anni Liimatainen, Hanna Kortejärvi, AnneJuppo

https://doi.org/10.1016/j.ijpharm.2020.119028

Congratulations!

Collaborative publication published:

Chemical analysis using 3D printed glass microfluidics
Eran Gal-Or, Yaniv Gershoni, Gianmario Scotti, Sofia M. E. Nilsson, Jukka Saarinen, Ville Jokinen, Clare J. Strachan, Gustav Boije af Gennäs, Jari Yli-Kauhaluoma, Tapio Kotiaho
A**l. Methods, first published on 14 Mar 2019

Chemical analysis using 3D printed glass microfluidics - A**lytical Methods (RSC Publishing) Additive manufacturing (3D printing) is a disruptive technology that is changing production systems globally. In addition, microfluidic devices are increasingly being used for chemical analysis and continuous production of chemicals. Printing of materials such as polymers and metals is already a rea...

Publication published:

Emmi AK Palomäki, Jouko K Yliruusi, Henrik V Ehlers. Effect of headspace gas on nucleation of amorphous paracetamol. Journal of Drug Delivery Science and Technology 2019;51;127-138

https://authors.elsevier.com/a/1YhOB_eKOQyRVy

Congratulations to the authors!

Effect of headspace gas on nucleation of amorphous paracetamol In this paper, the effect of the gaseous environment on recrystallization of amorphous paracetamol was investigated. The experiments were conducted wi…

FIP Industrial pharmacy section proudly presents an accepted manuscript in Clinical trials of a study done in collaboration with Bayer in Germany:

A.-L. Saarela, A. Walzer, A.M. Juppo, 2019.
Use of telephone and web interfaces of Interactive Response Technology at clinical investigator sites in clinical trials.
Accepted in Clinical Trials: Journal of the Society for Clinical Trials, IF=2.707

Congratulations to the authors!

FIP people were participating in excellent Nordic POP 1st Annual Meeting in Oslo (Holmenkollen) in January 14-16th 2019.

Presentations included:

-a keynote lecture: "Non-linear optical imaging in pharmaceutical applications from cells to solid-state" (Jukka Saarinen)

-an oral presentation: First of the kind – the apparent pH-solubility profile of an amorphous drug using the Single Particle A**lysis (SPA) method" (Jernej Štukelj)

-poster presentation: Surface crystallization upon storage and dissolution visualized with multimodal nonlinear imaging (Dunja Novakovic)

-poster presentation: Monitoring solid-state transformations in amorphous slurries in situ with low-frequency Raman spectroscopy (Jaana Koskela)

Award: The Finnish Pharmaceutical Society's "The Most Outstanding Pharmaceutical Research Article" award was granted to Novakovic et al.

Article was: "Multimodal Nonlinear Optical Imaging for Sensitive Detection of Multiple Pharmaceutical Solid-State Forms and Surface Transformations"
published in A**lytical Chemistry:
A**l. Chem. 2017, 89, 21, 11460-11467
https://pubs.acs.org/doi/10.1021/acs.analchem.7b02639

Congratulations!

On a Helsinki One Health day (2.11.2018) professor Anne Juppo (FIP) had a presentation about cat medications titled in Finnish as: "Mitä yhteistä on kissojen ja pienten lasten lääkinnässä?

This is the link for the video (in Finnish) of the event including the Anne's presentation:

Helsinki One Health Helsinki One Health -päivänä Helsingin yliopiston tutkijat keskustelevat Tiedekulmassa ruokaturvallisuudesta, translationaalisesta lääketieteestä sekä eläinten terveydestä ja hyvinvoinnista. ELÄINTEN TERVEYS JA HYVINVOINTI "Mikä seuraeläintä yskittää? - Koiralla voi olla keuhkotu...

Publication accepted (Biotechnology Journal, First published: 23 October 2018)

Cell‐Nanoparticle Interactions at Sub(nanometer) Resolution A**lysed by Electron Microscopy and Correlative Coherent Anti‐Stokes Raman Scattering

Jukka Saarinen, Friederike Gütter, Mervi Lindman, Mikael Agopov, Sara J. Fraser‐Miller, Regina Scherließ, Eija Jokitalo, Hélder A. Santos, Leena Peltonen, Antti Isomäki, Clare J. Strachan

https://doi.org/10.1002/biot.201800413

Publication published (29 September 2018):

Pharmacy 2018, 6(4)

The Use of Video Instructions in Patient Education Promoting Correct Technique for Dry Powder Inhalers: An Investigation on Inhaler-Naïve Individuals

Sofia von Schantz , Nina Katajavuori and Anne M. Juppo

https://doi.org/10.3390/pharmacy6040106

Congratulations!

Collaborative publication published:

European Journal of Pharmaceutics and Biopharmaceutics 132 (2018) 112–126

Preparation and characterization of multi-component tablets containing co-amorphous salts: Combining multimodal non-linear optical imaging with established analytical methods

Rami Ojarinta, Jukka Saarinen, Clare J. Strachan, Ossi Korhonen, Riikka Laitinen

https://authors.elsevier.com/c/1XoBL3Lfa-4hbN

Publication accepted (September 24, 2018):

Molecular Pharmaceutics https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.8b00840

Understanding dissolution and crystallization with imaging: a surface point of view

Dunja Novakovic, Antti Isomäki, Bibi Pleunis, Sara J. Fraser-Miller, Leena Peltonen, Timo Laaksonen, and Clare J. Strachan

Congratulations to the authors!