15/08/2023
Novel human lymph node-derived matrix supports the adhesion of metastatic oral carcinoma cells
Novel human lymph node-derived matrix supports the adhesion of metastatic oral carcinoma cells - BMC Cancer
Background 3D culture is increasingly used in cancer research, as it allows the growth of cells in an environment that mimics in vivo conditions. Metastases are the primary cause of morbidity and mortality in cancer patients, and solid tumour metastases are mostly located in lymph nodes. Currently,....
25/07/2023
The effect of matrices on the gene expression profile of patient-derived head and neck carcinoma cells for in vitro therapy testing
The effect of matrices on the gene expression profile of patient-derived head and neck carcinoma cells for in vitro therapy testing - Cancer Cell International
Objective Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive tumor with a 5-year mortality rate of ~ 50%. New in vitro methods are needed for testing patients’ cancer cell response to anti-cancer treatments. We aimed to investigate how the gene expression of fresh carcinoma tis...
25/04/2023
Evaluation of in vitro and in vivo personalized cancer treatment assays for oral squamous cell carcinoma
Evaluation of in vitro and in vivo personalized cancer treatment assays for oral squamous cell carcinoma
Oral squamous cell carcinoma (OSCC) is a common cancer with a high heterogeneity and few approved treatments. OSCC is one of the least explored areas …
