Ziemert Lab

Ziemert Lab The Ziemert lab is a research group interested in secondary metabolites from bacteria.

We are developing bioinformatic tools to facilitate genome mining of bacteria to discover new natural products as important drug leads. We also focus on the evolution of these diverse chemical compounds in their natural environments.

A nice story about Kistamicin Biosynthesis and Evolution. Great work from Evi Stegmann and Max Cryle, thanks for includi...
21/06/2019

A nice story about Kistamicin Biosynthesis and Evolution. Great work from Evi Stegmann and Max Cryle, thanks for including me in this study :-).

Kistamicin is a structurally divergent glycopeptide antibiotic (GPA) that contains a unique 15-membered A-O-B ring. Here, the authors obtained a crystal structure of the kistamicin OxyA/X-domain complex and analysed the cyclisation cascade leading to the formation of the A-O-B ring.

21/06/2019

Here an article in German about our research:

Our autoMLST paper is out. Happy tree building everybody!
23/04/2019

Our autoMLST paper is out. Happy tree building everybody!

Abstract. Understanding the evolutionary background of a bacterial isolate has applications for a wide range of research. However generating an accurate specie

See the new dream team of the ! Welcome Direnc and Shrikant !!! Excited for your research to come 😊
30/10/2018

See the new dream team of the ! Welcome Direnc and Shrikant !!! Excited for your research to come 😊

“See the new dream team of the ! Welcome Direnc and Shrikant !!! Excited for your research to come 😊”

The Ziemertlab produced its first PhD!!!Congrats Dr. Alanjary for an awesome thesis and defense with "summa cm laude"! ...
10/10/2018

The Ziemertlab produced its first PhD!!!
Congrats Dr. Alanjary for an awesome thesis and defense with "summa cm laude"! We are very proud of you and will miss you! Also the biggest thanks to the group for organizing and making the hat :-)

Genome Miners in climbing mood :-)! For our goodbye to Helena we went climbing and zip lining! What fun, we will miss yo...
24/06/2018

Genome Miners in climbing mood :-)! For our goodbye to Helena we went climbing and zip lining! What fun, we will miss you so much Helena!

Yay!!! Martina’s work on comparative genomics of secondary metabolites in the genus Amycolatopsis is finally out! Thanks...
01/06/2018

Yay!!! Martina’s work on comparative genomics of secondary metabolites in the genus Amycolatopsis is finally out! Thanks to all co-authors!

Genome mining tools have enabled us to predict biosynthetic gene clusters that might encode compounds with valuable functions for industrial and medical applications. With the continuously increasing number of genomes sequenced, we are confronted with an overwhelming number of predicted clusters. In...

Interested in developing bioinformatics tools for natural product discovery? Come join the team:
23/04/2018

Interested in developing bioinformatics tools for natural product discovery? Come join the team:

The beta version of our auto multi locus species tree (autoMLST) tool is online and running. Happy species tree building...
10/04/2018

The beta version of our auto multi locus species tree (autoMLST) tool is online and running. Happy species tree building 😊:

Phylogeny is built using all MLST genes from query and reference organisms using either a concatenated gene or coalescent tree method.

Organizing a conference? Looking for a plenary speaker? Here is a list of female P*s in the field of natural products: h...
29/12/2017

Organizing a conference? Looking for a plenary speaker? Here is a list of female P*s in the field of natural products: https://docs.google.com/spreadsheets/d/11umSEQKpIknwR2dEWgl0hDhAKw7PilFIjFLusinfnU8/edit =0
Additions are highly encouraged! No more excuses!

Sheet1 Scientists studying natural products( female) Know more women P*s in Natural Product Research? Please submit names and affiliations here:, womeninnpr. ziemertlab. com Please direct questions and comments to the curators: Dr. Nadine Ziemert, Univ. Tubingen, nadine. ziemert@ uni-tuebin...

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Auf Der Morgenstelle 28
Tübingen
72076

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