23/09/2021
Our group had a fantastic retreat at the beach of Warnemünde!
The Department for General Microbiology is part of the Institute of Microbiology & Genetics at the Georg-August-University Göttingen Dr. Jörg Stülke.
The General Microbiology combines five different workgroups under the head of Prof. The research mainly focuses on central metabolic pathways and their regulation in Bacillus subtilis or Escherichia coli. Besides this three workgroups concentrate on the investigation of the human pathogens Listeria monocytogenes, Mycoplasma pneumoniae and Staphylococcus aureus.
23/09/2021
Our group had a fantastic retreat at the beach of Warnemünde!
14/09/2021
Read Tiago's new paper on SynWiki the database for the minimal artificial organism Syn3A!
Tiago Pedreira Neil Singh
SynWiki: Functional annotation of the first artificial organism Mycoplasma mycoides JCVI‐syn3A The new field of synthetic biology aims at the creation of artificially designed organisms. A major breakthrough in the field was the generation of the artificial synthetic organism Mycoplasma mycoid...
17/07/2021
PhD ceremony for Björn Richts and Patrick Faßhauer
Great work by colleagues and friends from Groningen! Oscar Kuipers
This helps to fully use the potential of MiniBacillus!
Rafts4Biotech
Unchaining miniBacillus PG10: relief of FlgM-mediated repression of autolysin genes | Applied and Environmental Microbiology Cell chaining in Bacillus subtilis is naturally observed in a subset of cells during exponential growth and during biofilm formation. However, the recently constructed large-scale genome-minimized B. subtilis strain PG10 displays a severe and permanent defect in cell separation, as it exclusively gr...
02/07/2021
The new study on the B. subtilis cold shock proteins appears just one day after the PhD defense of Patrick Faßhauer!
Very good collaboration with colleagues in Greifswald and Bielefeld!
https://www.mdpi.com/2076-2607/9/7/1434
23/06/2021
Read the new paper from Martin Benda, Patrick Faßhauer, Simon Wölfel, And Katrin Gunka! Great collaboration with Libor Krásný ans Stefan Klumpp!
Quasi-essentiality of RNase Y in Bacillus subtilis is caused by its critical role in the control of mRNA homeostasis Abstract. RNA turnover is essential in all domains of life. The endonuclease RNase Y (rny) is one of the key components involved in RNA metabolism of the model
18/03/2021
Larissa Krüger receives the VAAM thesis Award! With the fourth award after Sven Halbedel, Lope Florez, and Jan Gundlach, Larissa continues a story of success! Congratulations!
18/03/2021
Great to have a student from our department among the award winners!
15/03/2021
Update of the Department homepage: https://www.uni-goettingen.de/en/577601.html
New paper by Larissa Krüger, Christina Herzberg, Dennis Wicke and colleagues from Göttingen and Hannover!
Find out how a c-di-AMP.binding protein can link potassium starvation to the stringent response in B. subtilis!
25/01/2021
Happy to see Larissa's new paper out!
Essentiality of c-di-AMP in Bacillus subtilis: Bypassing mutations converge in potassium and glutamate homeostasis Author summary Bacteria are exposed to constantly changing environmental conditions. In order to respond to these changes, they use nucleotide second messengers to transduce external signals and translate them into a specific cellular response. Among the repertoire of bacterial second messenger nucl...
06/01/2021
Nice paper to which our former lab member Martin Benda has contributed!
Effects of DNA Topology on Transcription from rRNA Promoters in Bacillus subtilis The expression of rRNA is one of the most energetically demanding cellular processes and, as such, it must be stringently controlled. Here, we report that DNA topology, i.e., the level of DNA supercoiling, plays a role in the regulation of Bacillus subtilis σA-dependent rRNA promoters in a gro...