Fachgebiet Medizinische Biotechnologie der Technischen Universität Berlin

27. September im Volksbad Jena: Podiumsdiskussion über unsere faszinierenden Stammzellen. Ich freu mich drauf! Organisiert vom German Stem Cell Network - GSCN - Deutsches Stammzellnetzwerk

Chlamydia infection is a well known sexually transmitted disease - but did you know that the bacteria can also infect the intestine? Experiments in organoids suggest this. Check out this paper by the group of Thomas Rudel in collaboration with us.

Chlamydia Can Settle in the Intestine Chlamydiae are sexually transmitted pathogens that can apparently survive in the human gut for a long time. Researchers from Würzburg and Berlin report this in the journal PLOS Pathogens.

The German Society for Hygiene and Microbiology (DGHM) had the major conference together with the VAAM in Würzburg to discuss the latest findings on infectious disease. So many scientific friends were there, the Infect-Net, GRK2157 and CRC Decide, such an amazing community! Sina Bartfeld as deputy chair of the group "Gastrointestinal Infections" of the DGHM co-organized and chaired one session. Save the date: 22.-24. September 2025 in Jena.

We had the Kick-Off meeting for "TOP-GUT", a new EU HORIZON MSCA Doctoral Network, in Berlin. It was amazing to see everybody and talk about the plans. We also heard fantastic keynote lectures from Stefan Krauss and Thomas Steger-Hartmann. The network provides training on organoids to model physiology and pathology of the gastrointestinal tract. www.topgut.eu

We published a new paper, just out in Stem Cell Reports. In this paper, we show that SARS-CoV-2 can infect intestinal, but not gastric organoids. The main entry receptor of the virus, ACE2, is differentially expressed in the different segments of the adult gastrointestinal tract and the differential expression pattern of ACE2 regulates SARS-CoV-2 infection. This was a collaborative effort between many groups, especially colleagues from the Charite Berlin, and it was the main work of PhD student Mindaugas Pauzuolis.

Congratulations Mindaugas Pauzuolis to the successful defense! Together with Carmen Aguilar, Emmanuel Saliba and many collaborators, Mindi has driven the identification of gastric pit cells as target cells of Helicobacter pylori (published) and he is finalizing another story on SARS-CoV-2 infection in the stomach. Well done Mindi! With the committee: Emmanuel Saliba, Redmond Smyth and Christine Krempl.

Join us in TOP-GUT, a Training for Organoids modelling Physiology and Pathology in the human gastrointestinal tract!
Within this Marie Sklodowska-Curie Doctoral Network ( DN) we are offering a PhD position to investigate the impact of carbohydrate complexity on host-microbe interaction in the gastrointestinal tract.
Be part of an excellent network that combines cutting-edge organoid and organ-on-a-chip technologies with ethical and regulatory aspects to make a real impact on in vitro model development and its implementation in personalized medicine.

Follow this link for application 👉 https://euraxess.ec.europa.eu/jobs/161246

Deadline for submission 🗓 30th November 2023

The TOP-GUT training network puts together 9 research groups and 3 industrial partners within Europe. More information: https://topgut.eu/

TopGut- Doctoral Network – Training for Organoids modelling Physiology and Pathology in the human gastrointestinal tract – Marie Sklodowska-Curie Doctoral Network Training for Organoids modelling Physiology and Pathology in the human gastrointestinal tractTOP-GUT: Call for applications for 11 Doctoral (PhD) Training Positions in the field of innovative preclinical model for advancing personalized medicine Deadline 30th November 2023Download Full Information a...

Ein neues Projekt am Fachgebiet: 3D-Bioprinting of patient-specific avatars for therapy prediction
In diesem Projekt entwickeln wir Biotinten, die auf die Anforderungen einzelner Zelltypen der Tumor-Mikroumgebung an die extrazelluläre Matrix zugeschnitten werden, insbesondere für epitheliale Krebszellen und Tumor-Immunzellen. Das Verbundprojekt zwischen der Cellbricks GmbH, der Charite Universitätsmedizin Berlin und der Technische Universität Berlin -
Fachbereich Medizinische Biotechnologie (Prof. Sina Bartfeld) wird im Rahmen des IBB Förderprogramms Pro FIT durch den Europäischen Fond für regionale Entwicklung (EFRE) kofinanziert.

https://www.static.tu.berlin/fileadmin/www/10002134/MedBT_Picture_Archive/230717-EFRE_Plakat_A3_Template.pdf