10/02/2026
Univerzity drží spolu: akutní sbírka pro univerzitu v Kyjevě na Ukrajině Aktuality z Masarykovy univerzity
Research laboratory DNA double-strand breaks (DSB) are among the most lethal forms of DNA damage.
DSBs are induced by a large number of endogenous and exogenous agents, as genotoxic chemicals and ionizing radiation, or due to replication of damaged DNA as well as collapse of a replication fork. DSB can either be properly repaired, restoring genomic integrity, or miss-repaired resulting in cell death, genomic instability, and cancer. Our group focuses on mechanisms of DSB repair using multi-disciplinary approach (biochemical, structural, computational, genetic, and single-molecule).
10/02/2026
Univerzity drží spolu: akutní sbírka pro univerzitu v Kyjevě na Ukrajině Aktuality z Masarykovy univerzity
20/01/2026
https://www.embolableadership.org/course/applying-design-principles-to-schematic-figures/
Design Principles for Schematic Figures - EMBO Lab Leadership Enhance your impact – use design principles to create compelling, clear schematic figures to communicate your research to a variety
09/12/2025
Happy Holidays! 🎄☃️🍾💕☮️
We really enjoyed visiting St. James church!
22/10/2025
https://www.em.muni.cz/student/17819-darujte-hodinu-tydne-ktera-detem-muze-zmenit-zivot
Darujte hodinu týdně, která dětem změní život Spolek Mise naděje aktuálně hledá nové dobrovolníky do projektu Online doučování dětí z dětských domovů, které jim v budoucnu otevírá nové možnosti na kvalitnější vzdělávání. Studenti MUNI mohou navíc získat i kredity za absolvování praxe.
08/10/2025
We are so proud to share with you the great news! Our SOČ student, Anna Černá, won the first prize at the European Union Contest for Young Scientists with her Biology project!! 🤩
CONGRATULATIONS!! 👏👏👏🥳
https://www.eucys2025.eu/en/participants/eucys-2025-winners/
Photo: Jānis Porietis
Splendid Palace. Apbalvošana.19.09.2025.
09/06/2025
Happy to see our newest collaborative manuscript published in Mol Cell! We hope this work will substantiate the role of biomolecular condensates in the regulation of DNA repair and chromatin organization.
Off-pore Nup98 condensates mobilize heterochromatic breaks and exclude Rad51 Merigliano et al. identified a non-canonical, “off-pore” role for nucleoporins in genome stability and in the spatial regulation of homologous recombination in multicellular eukaryotes. Nup98 condensates form at DNA breaks within pericentromeric heterochromatin to prevent aberrant recombination ...
02/12/2024
We are grateful to have received a 3-year research grant from the Czech Science Foundation, in collaboration with Karel Kubíček, to study the structure and biological role of the RAD51 protein. 🤩
https://www.facebook.com/GrantovaAgenturaCR/
15/11/2024
Our PI Lumir Krejci is among the newly elected EMBO members. Congratulations!! 😃
04/11/2024
Hana Polášek-Sedláčková, former member of our lab, presents her work as an EMBO Installation grantee in Heidelberg at the Meeting of the EMBO Communities.
15/10/2024
We are very happy to share the fantastic news! 😃Anna Černá, a high school student in our lab, has won the Czech state competition (SOČ) in Molecular Biology! 🎉Let’s wish her luck in her future endeavours! 🍀
https://www.soc.cz/
19/09/2024
https://www.embl.org/about/info/course-and-conference-office/events/ees25-05/
The ageing genome: from mechanisms to disease – Course and Conference Office Registration is not yet open for this event. If you are interested in receiving more information please register your interest.